Abstract: The present invention discloses a stable ultra long acting injectable solution comprising Insulin glargine, collagen and one or more pharmaceutically acceptable excipients or carrier at pH 2-5. The present invention also discloses the process for preparing the said composition and its use in treatment of metabolic disorders including diabetes mellitus.

Abstract: The present invention relates to a composition comprising a Salvia miltiorrhiza extract for prevention and treatment of depression in menopausal women. The Salvia miltiorrhiza extract of the present invention is characterized by regulating the release of luteinizing hormone and follicle-stimulating hormone and increasing the release of serotonin and norepinephrine to prevent, alleviate, and treat the hormonal change and depression occurring after menopause. In addition, since the raw material is highly stable, the composition comprising a danshensu-containing Salvia miltiorrhiza extract as an active ingredient retains the efficacy during long-term storage and thus can be suitable for use as an industrial substance.