Abstract: Polynucleotides encoding a nonfunctional mutant form of the Brother of Regulator of Imprinted Sites (BORIS) molecule, nonfunctional mutated BORIS protein, polypeptide or peptide and modified protein forms of BORIS are described. These molecules are used as a therapeutic vaccine against cancer.
Type:
Grant
Filed:
August 24, 2009
Date of Patent:
February 14, 2012
Assignee:
Uni Vax
Inventors:
Michael G Agadjanyan, Anahit Ghochikyan