Patents Assigned to UNION LIFE SCIENCES LTD.
  • Sulfonamide Derivatives Having Carbonic Anhydrase Inhibiting Activity and their Use as Therapeutic and Diagnostic Agents
    Publication number: 20080138291
    Abstract: The present invention discloses sulfonamide A-(Q)n—Ar—SChNHR which are CA IX-selective inhibitors, which selectively bind to the enzyme under hypoxic conditions and are able to reverse the tumor acidification mediated by the enzyme. These compounds are useful in anticancer therapies based on tumor-associated CA isozyme inhibition as well as for hypoxic tumor imaging.
    Type: Application
    Filed: June 20, 2006
    Publication date: June 12, 2008
    Applicant: UNION LIFE SCIENCES LTD.
    Inventors: Claudiu T. Supuran, Andrea Scozzafava