Patents Assigned to UNION UNIVERSITY
  • NADPH oxidase inhibitors and uses thereof
    Patent number: 11236053
    Abstract: This disclosure relates to compounds and methods of treating or preventing a Nox related disease or condition comprising administering to a subject in need thereof a Nox inhibitor or pharmaceutical compositions comprising a Nox inhibitor disclosed herein, derivatives, or compounds disclosed herein optionally substituted with one or more substitutes including optional salt and prodrug forms. In certain embodiments, this disclosure relates to sulfonylurea compounds and uses reported herein.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: February 1, 2022
    Assignees: Emory University, Mercer University, Howard University, Union University
    Inventors: Osman Güner, Bernard Lassegue, Kathy Griendling, Qian Xu, David Brown, J. Phillip Bowen, Amol Kulkarni, E. Blake Watkins
  • Methods for preparation of substituted pyridines and related novel compounds
    Patent number: 11117893
    Abstract: The present invention relates to novel methods of preparation of substituted pyridines and the compounds produced therefrom. In particular, the present invention provides efficient methods for the construction of diversely substituted pyridines, with varying substitution patterns under simple and metal-free conditions with high atom- and pot-economy and excellent functional group tolerance, and which are useful for the synthesis of natural products.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: September 14, 2021
    Assignee: Union University
    Inventors: Edmond Blake Watkins, Dilipkumar Uredi, Damoder Reddy Motati
  • Solenopsin and derivatives, therapeutic compositions; and methods related thereto
    Patent number: 9592226
    Abstract: This disclosure relates to solenopsin derivatives, pharmaceutical compositions, and therapeutic uses related thereto. In certain embodiments, the disclosure relates to compounds of the following formula: or salts, esters or prodrugs thereof as described herein.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: March 14, 2017
    Assignees: Emory University, Mercer University, Union University
    Inventors: Jack L. Arbiser, J. Philip Bowen, E. Blake Watkins
  • SOLENOPSIN AND DERIVATIVES, THERAPEUTIC COMPOSITIONS, AND METHODS RELATED THERETO
    Publication number: 20140335079
    Abstract: This disclosure relates to solenopsin derivatives, pharmaceutical compositions, and therapeutic uses related thereto. In certain embodiments, the disclosure relates to compounds of the following formula: or salts, esters or prodrugs thereof as described herein.
    Type: Application
    Filed: May 7, 2014
    Publication date: November 13, 2014
    Applicants: EMORY UNIVERSITY, UNION UNIVERSITY, MERCER UNIVERSITY
    Inventors: Jack L. Arbiser, J. Philip Bowen, E. Blake Watkins