Patents Assigned to UNION UNIVERSITY
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Patent number: 11236053Abstract: This disclosure relates to compounds and methods of treating or preventing a Nox related disease or condition comprising administering to a subject in need thereof a Nox inhibitor or pharmaceutical compositions comprising a Nox inhibitor disclosed herein, derivatives, or compounds disclosed herein optionally substituted with one or more substitutes including optional salt and prodrug forms. In certain embodiments, this disclosure relates to sulfonylurea compounds and uses reported herein.Type: GrantFiled: July 26, 2018Date of Patent: February 1, 2022Assignees: Emory University, Mercer University, Howard University, Union UniversityInventors: Osman Güner, Bernard Lassegue, Kathy Griendling, Qian Xu, David Brown, J. Phillip Bowen, Amol Kulkarni, E. Blake Watkins
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Patent number: 11117893Abstract: The present invention relates to novel methods of preparation of substituted pyridines and the compounds produced therefrom. In particular, the present invention provides efficient methods for the construction of diversely substituted pyridines, with varying substitution patterns under simple and metal-free conditions with high atom- and pot-economy and excellent functional group tolerance, and which are useful for the synthesis of natural products.Type: GrantFiled: September 24, 2019Date of Patent: September 14, 2021Assignee: Union UniversityInventors: Edmond Blake Watkins, Dilipkumar Uredi, Damoder Reddy Motati
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Patent number: 9592226Abstract: This disclosure relates to solenopsin derivatives, pharmaceutical compositions, and therapeutic uses related thereto. In certain embodiments, the disclosure relates to compounds of the following formula: or salts, esters or prodrugs thereof as described herein.Type: GrantFiled: July 8, 2015Date of Patent: March 14, 2017Assignees: Emory University, Mercer University, Union UniversityInventors: Jack L. Arbiser, J. Philip Bowen, E. Blake Watkins
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Publication number: 20140335079Abstract: This disclosure relates to solenopsin derivatives, pharmaceutical compositions, and therapeutic uses related thereto. In certain embodiments, the disclosure relates to compounds of the following formula: or salts, esters or prodrugs thereof as described herein.Type: ApplicationFiled: May 7, 2014Publication date: November 13, 2014Applicants: EMORY UNIVERSITY, UNION UNIVERSITY, MERCER UNIVERSITYInventors: Jack L. Arbiser, J. Philip Bowen, E. Blake Watkins
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Patent number: 8490507Abstract: A rotary swash plate type continuously variable transmission comprises a driving mechanism, an output mechanism and a casing 24. The driving mechanism comprises a rotational swash plate 9 with variable angle of inclination and at least three slide stems which are disposed parallel and equiangular with each other. Each slide stem is equipped with a one-way rotary helical gear 13 at one end, and contacts with and slides on the surface of the swash plate at the other end. The output mechanism comprises a one-way rotational output shaft 16 and a larger helical gear 14 which is disposed on the output shaft 16 and meshed with the helical gears 13. The transmission according to the invention is compact in view of structure and smooth in view of its output rotational speed. Moreover, the minimal rotational speed may be zero.Type: GrantFiled: November 12, 2009Date of Patent: July 23, 2013Assignee: Beijing Union UniversityInventor: Jiandong Sun
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Publication number: 20110146428Abstract: The invention relates to a rotary swash plate type continuously variable transmission, which comprises a driving mechanism, an output mechanism and a casing 24. Said driving mechanism comprises a rotational swash plate 9 with variable angle of inclination and at least three slide stems which are disposed parallel and equiangular with each other. Each slide stem is equipped with a one-way rotary bevel wheel 13 at one end, and contacts with and slides on the surface of the swash plate at the other end. Said output mechanism comprises a one-way rotational output shaft 16 and a larger bevel wheel 14 which is disposed on the output shaft 16 and meshed with the bevel wheels 13. The transmission according to the invention is compact in view of structure and smooth in view of its output rotational speed. Axial lines of the input shaft and the output shaft may be coincident so it can be a coaxial continuously variable transmission. Moreover, the minimal rotational speed may be zero.Type: ApplicationFiled: October 12, 2009Publication date: June 23, 2011Applicant: BEIJING UNION UNIVERSITYInventor: Jiandong Sun
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Patent number: 7905656Abstract: A passive differential calorimeter, comprising an inflow control valve (2?), differential measurement means (4?) including the driving part of an input water meter (15) and the driving part of an output water meter (16), a back flow control valve (9?) and connecting pipes between them, wherein both the inflow control valve and the output flow control valve being temperature controlled valve, i.e.Type: GrantFiled: March 31, 2008Date of Patent: March 15, 2011Assignee: Beijing Union UniversityInventor: Jiandong Sun
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Patent number: 7893947Abstract: A method for extracting edge with subpixel accuracy in photogrammetry, comprising steps of: a. capturing into a computer a picture, of which the edge is to be extracted; b. defining as a cell four neighboring pixels that form a square; c. recognizing the type of each cell composed of the four pixels; d. finding out side or sides of the cell that intersect with, the edge and figuring out the subpixel accuracy coordinates of the intersection points by linear interpolation; and e. connecting the intersection points to extract the edge. By this method edge curve is extracted rapidly and accurately. The edge determined in this way can be subpixel accurate.Type: GrantFiled: July 26, 2007Date of Patent: February 22, 2011Assignee: Beijing Union UniversityInventor: Xin Fang
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Publication number: 20080273571Abstract: A passive differential calorimeter, comprising an inflow control valve (2?), differential measurement means (4?) including the driving part of an input water meter (15) and the driving part of an output water meter (16), a back flow control valve (9?) and connecting pipes between them, wherein both the inflow control valve and the output flow control valve being temperature controlled valve, i.e.Type: ApplicationFiled: March 31, 2008Publication date: November 6, 2008Applicant: Beijing Union UniversityInventor: Jiandong Sun
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Patent number: 4921808Abstract: The present disclosure relates to an improved method based on hormone-receptor binding for the determination of follicle stimulating hormone and to improved reagents useful for the determination of follicle stimulating hormone in a hormone-receptor binding assay.Type: GrantFiled: June 25, 1986Date of Patent: May 1, 1990Assignee: The Albany Medical College of Union UniversityInventors: Alan L. Schneyer, Patrick M. Sluss, Bosukonda Dattatreyamurty, Leo E. Reichert, Jr.
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Patent number: 4871488Abstract: The present disclosure relates to novel liposome compositions and methods for their preparation. Utilization of the present invention provides an efficient reconstitution of membrane proteins into large (0.1 to 2 micron diameter) phospholipid vesicles with a large, internal aqueous space. The method has been exemplified with the use of glycoproteins of influenza (A/PR8/34) and Sendai (parainfluenza type I) viruses. The method comprises (A) extracting out the desired membrane protein from a source biological material with an extraction buffer comprising a detergent; (B) mixing the extract with a phospholipid solution and deriving a cochleate intermediate; and (C) forming large phospholipid vesicles with integrated membrane protein in a biologically active state.Type: GrantFiled: April 13, 1987Date of Patent: October 3, 1989Assignee: Albany Medical College of Union UniversityInventors: Raphael J. Mannino, Susan G. Fogerite
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Patent number: PP22198Abstract: A new cultivar of rose, ‘Te Jiao’, characterized by its upright, climbing habit, semi-glossy green foliage, its semi-double pink flowers, its repeat blooming habit even through hot weather, its disease resistance, and its vigorous growth habit with minimal seed production.Type: GrantFiled: July 16, 2010Date of Patent: October 18, 2011Assignee: Beijing Union UniversityInventors: Bao Ping Qiu, Zhang Lei, Ding Yan Li
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Patent number: PP22243Abstract: A new cultivar of rose plant named ‘Te Qiao’, a shrub rose characterized by its upright, compact, densely-branched habit, its semi-glossy green foliage, its red-purple, single flowers, its repeat blooming habit even through hot weather and its vigorous growth with minimal seed production.Type: GrantFiled: July 16, 2010Date of Patent: November 15, 2011Assignee: Beijing Union UniversityInventors: Bao Ping Qiu, Ding Yan Li, Zhang Lei