Patents Assigned to UNION UNIVERSITY
  • Patent number: 11236053
    Abstract: This disclosure relates to compounds and methods of treating or preventing a Nox related disease or condition comprising administering to a subject in need thereof a Nox inhibitor or pharmaceutical compositions comprising a Nox inhibitor disclosed herein, derivatives, or compounds disclosed herein optionally substituted with one or more substitutes including optional salt and prodrug forms. In certain embodiments, this disclosure relates to sulfonylurea compounds and uses reported herein.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: February 1, 2022
    Assignees: Emory University, Mercer University, Howard University, Union University
    Inventors: Osman Güner, Bernard Lassegue, Kathy Griendling, Qian Xu, David Brown, J. Phillip Bowen, Amol Kulkarni, E. Blake Watkins
  • Patent number: 11117893
    Abstract: The present invention relates to novel methods of preparation of substituted pyridines and the compounds produced therefrom. In particular, the present invention provides efficient methods for the construction of diversely substituted pyridines, with varying substitution patterns under simple and metal-free conditions with high atom- and pot-economy and excellent functional group tolerance, and which are useful for the synthesis of natural products.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: September 14, 2021
    Assignee: Union University
    Inventors: Edmond Blake Watkins, Dilipkumar Uredi, Damoder Reddy Motati
  • Patent number: 9592226
    Abstract: This disclosure relates to solenopsin derivatives, pharmaceutical compositions, and therapeutic uses related thereto. In certain embodiments, the disclosure relates to compounds of the following formula: or salts, esters or prodrugs thereof as described herein.
    Type: Grant
    Filed: July 8, 2015
    Date of Patent: March 14, 2017
    Assignees: Emory University, Mercer University, Union University
    Inventors: Jack L. Arbiser, J. Philip Bowen, E. Blake Watkins
  • Publication number: 20140335079
    Abstract: This disclosure relates to solenopsin derivatives, pharmaceutical compositions, and therapeutic uses related thereto. In certain embodiments, the disclosure relates to compounds of the following formula: or salts, esters or prodrugs thereof as described herein.
    Type: Application
    Filed: May 7, 2014
    Publication date: November 13, 2014
    Applicants: EMORY UNIVERSITY, UNION UNIVERSITY, MERCER UNIVERSITY
    Inventors: Jack L. Arbiser, J. Philip Bowen, E. Blake Watkins
  • Patent number: 8490507
    Abstract: A rotary swash plate type continuously variable transmission comprises a driving mechanism, an output mechanism and a casing 24. The driving mechanism comprises a rotational swash plate 9 with variable angle of inclination and at least three slide stems which are disposed parallel and equiangular with each other. Each slide stem is equipped with a one-way rotary helical gear 13 at one end, and contacts with and slides on the surface of the swash plate at the other end. The output mechanism comprises a one-way rotational output shaft 16 and a larger helical gear 14 which is disposed on the output shaft 16 and meshed with the helical gears 13. The transmission according to the invention is compact in view of structure and smooth in view of its output rotational speed. Moreover, the minimal rotational speed may be zero.
    Type: Grant
    Filed: November 12, 2009
    Date of Patent: July 23, 2013
    Assignee: Beijing Union University
    Inventor: Jiandong Sun
  • Publication number: 20110146428
    Abstract: The invention relates to a rotary swash plate type continuously variable transmission, which comprises a driving mechanism, an output mechanism and a casing 24. Said driving mechanism comprises a rotational swash plate 9 with variable angle of inclination and at least three slide stems which are disposed parallel and equiangular with each other. Each slide stem is equipped with a one-way rotary bevel wheel 13 at one end, and contacts with and slides on the surface of the swash plate at the other end. Said output mechanism comprises a one-way rotational output shaft 16 and a larger bevel wheel 14 which is disposed on the output shaft 16 and meshed with the bevel wheels 13. The transmission according to the invention is compact in view of structure and smooth in view of its output rotational speed. Axial lines of the input shaft and the output shaft may be coincident so it can be a coaxial continuously variable transmission. Moreover, the minimal rotational speed may be zero.
    Type: Application
    Filed: October 12, 2009
    Publication date: June 23, 2011
    Applicant: BEIJING UNION UNIVERSITY
    Inventor: Jiandong Sun
  • Patent number: 7905656
    Abstract: A passive differential calorimeter, comprising an inflow control valve (2?), differential measurement means (4?) including the driving part of an input water meter (15) and the driving part of an output water meter (16), a back flow control valve (9?) and connecting pipes between them, wherein both the inflow control valve and the output flow control valve being temperature controlled valve, i.e.
    Type: Grant
    Filed: March 31, 2008
    Date of Patent: March 15, 2011
    Assignee: Beijing Union University
    Inventor: Jiandong Sun
  • Patent number: 7893947
    Abstract: A method for extracting edge with subpixel accuracy in photogrammetry, comprising steps of: a. capturing into a computer a picture, of which the edge is to be extracted; b. defining as a cell four neighboring pixels that form a square; c. recognizing the type of each cell composed of the four pixels; d. finding out side or sides of the cell that intersect with, the edge and figuring out the subpixel accuracy coordinates of the intersection points by linear interpolation; and e. connecting the intersection points to extract the edge. By this method edge curve is extracted rapidly and accurately. The edge determined in this way can be subpixel accurate.
    Type: Grant
    Filed: July 26, 2007
    Date of Patent: February 22, 2011
    Assignee: Beijing Union University
    Inventor: Xin Fang
  • Publication number: 20080273571
    Abstract: A passive differential calorimeter, comprising an inflow control valve (2?), differential measurement means (4?) including the driving part of an input water meter (15) and the driving part of an output water meter (16), a back flow control valve (9?) and connecting pipes between them, wherein both the inflow control valve and the output flow control valve being temperature controlled valve, i.e.
    Type: Application
    Filed: March 31, 2008
    Publication date: November 6, 2008
    Applicant: Beijing Union University
    Inventor: Jiandong Sun
  • Patent number: 4921808
    Abstract: The present disclosure relates to an improved method based on hormone-receptor binding for the determination of follicle stimulating hormone and to improved reagents useful for the determination of follicle stimulating hormone in a hormone-receptor binding assay.
    Type: Grant
    Filed: June 25, 1986
    Date of Patent: May 1, 1990
    Assignee: The Albany Medical College of Union University
    Inventors: Alan L. Schneyer, Patrick M. Sluss, Bosukonda Dattatreyamurty, Leo E. Reichert, Jr.
  • Patent number: 4871488
    Abstract: The present disclosure relates to novel liposome compositions and methods for their preparation. Utilization of the present invention provides an efficient reconstitution of membrane proteins into large (0.1 to 2 micron diameter) phospholipid vesicles with a large, internal aqueous space. The method has been exemplified with the use of glycoproteins of influenza (A/PR8/34) and Sendai (parainfluenza type I) viruses. The method comprises (A) extracting out the desired membrane protein from a source biological material with an extraction buffer comprising a detergent; (B) mixing the extract with a phospholipid solution and deriving a cochleate intermediate; and (C) forming large phospholipid vesicles with integrated membrane protein in a biologically active state.
    Type: Grant
    Filed: April 13, 1987
    Date of Patent: October 3, 1989
    Assignee: Albany Medical College of Union University
    Inventors: Raphael J. Mannino, Susan G. Fogerite
  • Patent number: PP22198
    Abstract: A new cultivar of rose, ‘Te Jiao’, characterized by its upright, climbing habit, semi-glossy green foliage, its semi-double pink flowers, its repeat blooming habit even through hot weather, its disease resistance, and its vigorous growth habit with minimal seed production.
    Type: Grant
    Filed: July 16, 2010
    Date of Patent: October 18, 2011
    Assignee: Beijing Union University
    Inventors: Bao Ping Qiu, Zhang Lei, Ding Yan Li
  • Patent number: PP22243
    Abstract: A new cultivar of rose plant named ‘Te Qiao’, a shrub rose characterized by its upright, compact, densely-branched habit, its semi-glossy green foliage, its red-purple, single flowers, its repeat blooming habit even through hot weather and its vigorous growth with minimal seed production.
    Type: Grant
    Filed: July 16, 2010
    Date of Patent: November 15, 2011
    Assignee: Beijing Union University
    Inventors: Bao Ping Qiu, Ding Yan Li, Zhang Lei