Patents Assigned to Unitech Pharmaceuticals, Inc.
  • Dynamic anticancer platinum compounds
    Patent number: 7160908
    Abstract: A series of dynamic platinum compounds for cancer treatment are described. The compounds may become active and inactive reversibly.
    Type: Grant
    Filed: March 4, 2004
    Date of Patent: January 9, 2007
    Assignee: Unitech Pharmaceuticals, Inc.
    Inventor: Jiajiu Shaw
  • Methods, compounds, and diagnostics for cancer treatment
    Patent number: 7125902
    Abstract: Methods of treating cancer employing isoxazole derivatives are described. Compounds and methods of using these compounds for isolating and/or detecting binding proteins, which may be indicative of a disease, are also described.
    Type: Grant
    Filed: May 28, 2004
    Date of Patent: October 24, 2006
    Assignee: Unitech Pharmaceuticals, Inc.
    Inventors: Jiajiu Shaw, An-Rong Lee, Wen-Hsin Huang
  • Methods of synthesizing flavonoids and chalcones
    Publication number: 20040242907
    Abstract: Simple and efficient total syntheses of flavonoids including baicalein, oroxylin A and wogonin are described herein. Simultaneous syntheses of oroxylin A and wogonin are also described.
    Type: Application
    Filed: May 28, 2004
    Publication date: December 2, 2004
    Applicant: Unitech Pharmaceuticals, Inc.
    Inventors: Jiajiu Shaw, An-Rong Lee, Wen-Hsin Huang
  • Controlled release delivery system of solid dosage form
    Patent number: 6770297
    Abstract: This invention relates to a controlled release delivery system of solid dosage form with a plurality of controls on the release of the active ingredient or ingredients.
    Type: Grant
    Filed: May 26, 2000
    Date of Patent: August 3, 2004
    Assignee: Unitech Pharmaceuticals, Inc.
    Inventor: Jiajiu Shaw
  • Leflunomide analogs for treating rheumatoid arthritis
    Patent number: 6727272
    Abstract: Novel leflunomide analogs were synthesized and evaluated in-vivo. Based on the in-vivo studies, these analogs are surprisingly effective for treating rheumatoid arthritis.
    Type: Grant
    Filed: July 15, 2002
    Date of Patent: April 27, 2004
    Assignee: Unitech Pharmaceuticals, Inc.
    Inventors: An-Rong Lee, Wen-Hsin Huang, Jiajiu Shaw
  • Carboplatin analogs for cancer treatment
    Patent number: 6548541
    Abstract: The synthesis and the use of a series of carboplatin analogs is disclosed. These carboplatin analogs may be represented by cis-Pt(II)L1L2, wherein each of L1 and L2, independently, is the carboxylate of phosphatidylserine, an &agr;-amino acid, a &bgr;-amino acid, or a derivative thereof, wherein each ligand is bidentate with —NH2 and —COO− as the binding sites. The complexes can be used in the treatment of cancer.
    Type: Grant
    Filed: April 18, 2000
    Date of Patent: April 15, 2003
    Assignee: Unitech Pharmaceuticals, Inc.
    Inventor: Jiajiu Shaw
  • Carboplatin analogs for cancer treatment
    Patent number: 6534096
    Abstract: The synthesis and the use of a series of carboplatin analogs is disclosed. These carboplatin analogs may be represented by cis-Pt(II)L1L2, wherein each of L1 and L2, independently, is the carboxylate of phosphatidylserine, an &agr;-amino acid, &bgr;-amino acid, or a derivative thereof, wherein each ligand is bidentate with —NH2 and —COO− as the binding sites. The complexes can be used in the treatment of cancer.
    Type: Grant
    Filed: April 25, 2002
    Date of Patent: March 18, 2003
    Assignee: Unitech Pharmaceuticals, Inc.
    Inventor: Jiajiu Shaw
  • Carboplatin analogs for cancer treatment
    Publication number: 20020165204
    Abstract: The synthesis and the use of a series of carboplatin analogs is disclosed. These carboplatin analogs may be represented by cis-Pt(II)L1L2, wherein each of L1 and L2, independently, is the carboxylate of phosphatidylserine, an &agr;-amino acid, a &bgr;-amino acid, or a derivative thereof, wherein each ligand is bidentate with —NH2 and —COO− as the binding sites. The complexes can be used in the treatment of cancer.
    Type: Application
    Filed: April 25, 2002
    Publication date: November 7, 2002
    Applicant: Unitech Pharmaceuticals, Inc.
    Inventor: Jiajiu Shaw
  • Carboplatin analogs for cancer treatment
    Patent number: 6458832
    Abstract: The synthesis and the use of a series of carboplatin analogs is disclosed. These carboplatin analogs may be represented by cis-Pt(II)L1L2, wherein each of L1 and L2, independently, is the carboxylate of phosphatidylserine, an &agr;-amino acid, a &bgr;-amino acid, or a derivative thereof, wherein each ligand is bidentate with —NH2 and —COO− as the binding sites. The complexes can be used in the treatment of cancer.
    Type: Grant
    Filed: April 18, 2000
    Date of Patent: October 1, 2002
    Assignee: Unitech Pharmaceuticals, Inc.
    Inventor: Jiajiu Shaw
  • Tacrine derivatives for treating Alzheimer's disease
    Patent number: 6194403
    Abstract: A series of tacrine derivatives has be synthesized and disclosed. These tacrine derivatives were claimed to be new and be useful for the treatment of Alzheimer's disease alone or in combination with other drugs for Alzheimer's disease. These tacrine derivatives may be formulated into suitable pharmaceutical dosage forms for the treatment of Alzheimer's disease.
    Type: Grant
    Filed: September 9, 1999
    Date of Patent: February 27, 2001
    Assignee: Unitech Pharmaceuticals, Inc.
    Inventors: Ming-Kuan Hu, Jiajiu Shaw
  • Dinuclear platinum complexes as cisplatin analogs for cancer treatment
    Patent number: 6130245
    Abstract: This invention comprises the synthesis and the use of a new class of cisplatin analogs. These analogs are complexes formed between tetrachloroplatinum (II) and triethylenetetraamine or its derivatives. The stoichiometric ratio between cisplatin and triethylenetetraamine or its derivatives is between 0.4:1 to 0.5:0.8. The complexes are to be used in cancer treatment; they may also be used to treat AIDS patients.
    Type: Grant
    Filed: October 26, 1998
    Date of Patent: October 10, 2000
    Assignee: Unitech Pharmaceuticals, Inc.
    Inventor: Jiajiu Shaw
  • N-benzoyl-.alpha.-alkylated azatyrosines as anticancer agents
    Patent number: 6037357
    Abstract: A series of N-benzoyl-.alpha.-alkylated azatyrosines has been synthesized and disclosed. Their in-vitro activities were positive against several human cancer cell lines and significantly more effective than L-azatyrosine. These azatyrosine derivatives were claimed to be new and be useful as anticancer agents alone or in combination with other anticancer agents. These azatyrosine derivatives may be formulated into suitable pharmaceutical dosage forms for the treatment of cancer.
    Type: Grant
    Filed: April 21, 1999
    Date of Patent: March 14, 2000
    Assignee: Unitech Pharmaceuticals, Inc.
    Inventor: Ming-Kuan Hu
  • Pharmaceutical composition comprised of cisplatin, and processes for making and using same
    Patent number: 6001817
    Abstract: A pharmaceutical composition, comprising cisplatin, a special carrier and, optionally, customary pharmaceutical excipients, is disclosed. The preparation of this pharmaceutical composition is also disclosed. The composition may be used to treat cancer and Acquired Immune Deficiency Syndrome (AIDS).
    Type: Grant
    Filed: January 12, 1998
    Date of Patent: December 14, 1999
    Assignee: Unitech Pharmaceuticals, Inc.
    Inventor: Jiajiu Shaw
  • Cisplatin analogs for cancer treatment
    Patent number: 5922689
    Abstract: This invention comprises the synthesis and the use of two cisplatin analogs ?Pt(NH.sub.3).sub.2 Cl(C.sub.10 H.sub.13 N.sub.5 O.sub.5)!Cl and ?Pt(NH.sub.3).sub.2 (C.sub.10 H.sub.13 N.sub.5 O.sub.5).sub.2 !Cl.sub.2, whereby (C.sub.10 H.sub.13 N.sub.5 O.sub.5) is guanosine. The stoichiometric ratio between cisplatin and guanosine may be 1:1 or 1:2. The complexes are to be used in cancer treatment, they may also be used to treat AIDS patients.
    Type: Grant
    Filed: March 17, 1997
    Date of Patent: July 13, 1999
    Assignee: Unitech Pharmaceuticals, Inc.
    Inventor: Jiajiu Shaw