Patents Assigned to United States Government as represented by the Secretary of the Dept. of Health and Human Services
  • METHODS FOR IDENTIFYING MARKERS FOR EARLY-STAGE HUMAN CANCER, CANCER PROGRESSION AND RECURRENCE
    Publication number: 20120316321
    Abstract: A method is described to identify secreted proteins identified with stages of malignancy of cancer. The proteins are initially identified by trapping them with a fluorescent protein containing vector that can insert in any gene. The secreted proteins are initially identified by their fluorescence. Secreted proteins identifying tumors with specific degrees of malignancy are isolated to determine if they can serve as markers of cancer progression.
    Type: Application
    Filed: June 15, 2012
    Publication date: December 13, 2012
    Applicants: The United States Government as Represented by the Secretary, Dept. of Health and Human Services, AntiCancer, Inc.
    Inventors: Mingxu XU, Yuying Tan, Levy Kopelovich
  • 3-deazaneplanocin, intermediates for it, and antiviral composition and method of treatment using it
    Patent number: 4968690
    Abstract: The new compound 3-deazaneplanocin A has been discovered to have potent anti-viral, anti-tumor activity and differentiating activity. A simple method for preparing 3-deazaneplanocin A has been developed involving nucleophilic substitution, which method can also be used to prepare a great variety of carbocyclic nucleosides.
    Type: Grant
    Filed: January 19, 1989
    Date of Patent: November 6, 1990
    Assignee: United States Government as represented by the Secretary of the Dept. of Health and Human Services
    Inventors: Victor E. Marquez, John S. Driscoll, Mu-Ill Lim, Christopher K. Tseng, Alberto Haces, Robert I. Glazer