Abstract: Disclosed is a method of identifying ?-synuclein expression, as a biomarker for adiposity and adiposity related disorders. Identification of ?-synuclein expression includes agonists and antagonists thereof which may be used in pharmaceutical compositions for the treatment of adiposity related disorders.

Abstract: A chemical composition comprising a linker agent and a compound comprising at least one UV-absorbing chromophore, wherein the linker agent is characterized by the general formula: wherein X1 and X2 are the same or different, and at least one of X1 or X2 is a functional group that bonds with the compound comprising at least one UV-absorbing chromophore, and b+f?2, Y comprises an O, N, or S that is substituted or unsubstituted, each a, b, c, e and f is ?0 and a+b+c+e+f?2, d is 0 or 1, n1 and n2 represent the number of hydrogen atoms required to complete the undesignated valencies, and m ranges from 1 to about 100 and each individual m unit may be the same or different.