Abstract: Provided is a mammalian T cell modified to express the Phf19 at a level that is higher than the level of Phf19 expressed by a T cell that has not been modified to express Phf19. Provided is a genetically-modified mammalian T cell comprising a genetic expression vector comprising (a) virally-, bacterially-, or both virally- and bacterially-derived genetic sequences and (b) a genetic sequence encoding Phf19, whereby the genetic sequence encoding Phf19 within the vector is expressed within the T cell. Pharmaceutical compositions, methods of treating a disease, and methods of inhibiting the differentiation of T cells by epigenetic reprogramming are also provided.

Abstract: The present invention provides for a release system for delaying application of chemical reagents in a lateral-flow immunoassay. A chemistry release fiber comprising a permeable membrane and a chemical release agent is used to delay chemical reagent delivery to the indicator of a lateral-flow immunoassay. Also disclosed is the related method of delaying application of chemical reagents in a lateral-flow immunoassay.

Abstract: A galvanic isolator circuit and method provide for galvanically isolating and current limiting a power source from a load. A direct current (DC) input voltage (“vin”) and an input current (“iin”) are received. A full- or half-bridge rectifier is switched to synthesize a first alternating voltage waveform that magnetically couples through a transformer to induce a second alternating voltage waveform with galvanic isolation from the first alternating voltage waveform, preventing potentially-faulted load from a source. The second alternating voltage waveform is rectified to produce a direct current (DC) output voltage (“vo”) having output current (“io”) through more than one drive transistor or diode. The more than one primary-side drive transistor is current limited to reduce or prevent brown-out, black-out, or protective race conditions in the non-faulted portions of DC power generation systems and DC distribution electrical power systems.

Abstract: Some aspects relate to methods of forming an epitaxial layer. In some examples, the methods include ejecting atoms from a molten metal sputtering material onto a heated crystalline substrate and growing a single epitaxial layer on the substrate from the ejected atoms, where the atoms are ejected with sufficient energy that the grown epitaxial layer has at least a partial rhombohedral lattice, and wherein the crystalline substrate is heated to a temperature of about 600 degrees Celsius or less, or about 500 degrees or less. Other aspects relate to materials, such as a material including a single epitaxial layer on top of a crystalline substrate, the layer including one or more semiconductor materials and having at least a partial rhombohedral lattice, or a substantially rhombohedral lattice.

Abstract: A simple-hinged flap assembly for a winged aircraft includes a simple-hinged flap having a leading airfoil section pivotably connected to a trailing airfoil section via a hinge, and an active flow control (AFC) actuator assembly. The assembly is connected to or integrally formed with the flap and includes upstream and downstream AFC actuators arranged in respective first and second rows, and collectively configured to provide first and second outlet mass flowrates. The downstream AFC actuators emit the second outlet mass flowrate at a rate that substantially exceeds the first outlet mass flowrate, such that the first outlet mass flowrate preconditions a boundary layer around the simple-hinged flap assembly. A winged aircraft includes a pneumatic power supply, fuselage, a wing connected to the fuselage, and the simple-hinged flap assembly.

Abstract: Examples are directed toward a system and method relating to mobile screening. For example, a mobile screening vehicle includes a passenger scanner that performs security scanning of a passenger on the mobile screening vehicle. The mobile screening vehicle also includes a verification system that verifies, consistent with the security scanning of passengers, that passengers on the mobile screening vehicle are approved to proceed to a secure area of a travel venue.

Abstract: An example method of performing searches by comparing regions includes identifying a search point contained in geo-located data. The search point is nearest in distance to a query location. A search region associated with the search point is determined. The search region includes neighbor points contained in the geo-located data that are nearest the search point. Centroids corresponding respectively to the plurality of neighbor points of the search region are determined. The centroids of the search region are compared to other centroids corresponding to other regions of the geo-located data. The number of other centroids that match with the plurality of centroids are counted, and the counts are placed in descending order, to list the other regions having the highest similarity first. An ordered list of the other regions is generated based on their respective similarities to the query region.

Abstract: A missile comprises a generally cylindrical body having a distal end and a proximal end; a nosecone having a pointed distal end and a proximal end, wherein the proximal ends of the body and nosecone are oriented toward each other; a forward angled section rotatably attached to the proximal end of the nosecone at its forward edge, the opposite end of the forward angled section having an angled edge perpendicular to the longitudinal axis except for the angle defined by the edge; a rear angled section rotatably attached to the proximal end of the body at its rear edge, the opposite end of the forward angled section having an angled edge matching the angled edge of the forward angled section, the angled edges of the forward angled section and the rear angled section being rotatably attached.

Abstract: A method to enhance security screening includes generating an augmented reality (AR) interface incorporating scan results from scanning a target in a security scanner. The method displays, to a user of an AR interface, the AR interface mapped to the target and determines guidance including an action relevant to addressing the scan results. The method displays, to the user via the AR interface, the guidance including the action for the user to carry out and monitors user actions. The method displays, to the user via the AR interface, confirmation that the user has carried out the action.

Abstract: High-performance optical-metasurface-based components configured to at frequencies of UV light and, in particular, in deep UV range and performing multiple optical-wavefront-shaping functions (among which there are high-numerical-aperture lensing, accelerating beam generation, and hologram projection). As a representative material for such components, hafnium oxide demands creation and establishment of a novel process of manufacture that is nevertheless based on general principles of Damascene lithography, to be compatible with existing technology and yet sufficient for producing high-aspect-ratio features that currently-used materials and processes simply do not deliver. The described invention opens a way towards low-form-factor, multifunctional ultraviolet nanophotonic platforms based on flat optical components and enabling diverse applications including lithography, imaging, spectroscopy, and quantum information processing.

Abstract: An apparatus for implementing a physically unclonable function via a network of interferometers implemented as a reconfigurable integrated optical circuit. The uncontrollable and non repeating fabrication variation in the manufacturing processes of integrated optics, combined with the sensitivity of interferometers creates inherently unique devices that can be used as reprogrammable physically unclonable function.

Abstract: The present application discloses a new form of ?-STAP, referred to herein as post ?-STAP or P?-STAP, which overcomes the drawbacks associated with existing ?-STAP techniques. The P?-STAP techniques described herein facilitate the generation of additional training data and homogenization after pulse compression. For example, P?-STAP techniques may apply a plurality of homogenization filters to a pulse compressed datacube generated from an input radar waveform, which produces a plurality of new pulse compressed datacubes with improved characteristics. Unlike existing ?-STAP techniques described above, which require pre-pulse compressed data to operate, the P?-STAP techniques disclosed in the present application are designed to utilize pulse compressed data, and therefore may be readily applied to legacy radar systems.

Abstract: In certain aspects, the present disclosure relates to a composition comprising a first compound that is a trigeminal nerve irritant, a second compound that is an animal repellent, and an acceptable carrier. The disclosure also relates to methods of repelling an animal from a substrate comprising applying to a substrate the compositions comprising a trigeminal nerve irritant and an animal repellent as described herein.

Abstract: Biomarkers tests which can be used to predict a positive or negative risk of preeclampsia are described. More specifically, a panel of biomarkers including MMP-7 and gpIIbIIIa, described. The test is useful to predict preeclampsia when a biological sample is obtained between the 16th and 22nd week of pregnancy. Prediction later in pregnancy can be achieved by a combination of Siglec-6, Activin A, ALCAM, and/or FCN2.

Abstract: A containment apparatus for collecting electrolyte from a battery relief vent is provided. The containment apparatus includes a body comprising a reservoir, a relief vent aperture, an internal baffle, and an upper vent aperture; a push-on connection that attaches the relief vent aperture to the battery relief vent; and a viewing window on an external side of the body. The containment apparatus attaches to a pressure relief vent on a battery to capture droplets of electrolyte that are released from the battery relief vent. Liquid electrolytes travel through the relief vent aperture and into the reservoir, and vaporized electrolyte condenses on the baffle and falls into the reservoir as droplets or travels past the baffle and is directed through the upper vent aperture via the walls. The device prevents electrolytes from accumulating on the outside of the battery and associated hardware within the vicinity of the battery.

Abstract: Modified natural killer (NK) or T cells expressing hematopoietic growth factor receptors are provided. In some aspects, the modified NK cells or T cells express a thrombopoietin receptor, an erythropoietin receptor, or a chimeric polypeptide including an extracellular domain of a thrombopoietin receptor, a transmembrane domain, and an intracellular domain including an interleukin-2 receptor beta intracellular signaling domain. Methods of treating a subject with cancer are also provided, including administering the modified NK cells or T cells to the subject in combination with a thrombopoietin receptor agonist or erythropoietin receptor agonist, and in some example, interleukin-2, particularly reduced or low-dose amounts of IL-2.

Abstract: Metapneumovirus (MPV) F proteins stabilized in a prefusion conformation, nucleic acid molecules and vectors encoding these proteins, and methods of their use and production are disclosed. In several embodiments, the MPV F proteins and/or nucleic acid molecules can be used to generate an immune response to MPV in a subject. In additional embodiments, the therapeutically effective amount of the MPV F ectodomain trimers and/or nucleic acid molecules can be administered to a subject in a method of treating or preventing MPV infection.

Abstract: A radial cutting cavity container includes a housing that defines a chamber for a shaped explosive charge. The housing is configured to allow a user to pack explosives therein. An airtight cavity is attached to the housing. The airtight cavity defines a standoff distance for the shaped explosive charge and has a concave surface adapted to form an explosive cutting jet. A liner is located between the housing and the airtight cavity. A support stand is attached to the container to allow the container to be mounted on a surface for creating a radial cut normal to the surface.

Abstract: An atomic vapor cell for performing RF measurements includes: a first optical window of transparent nonconducting material free of electrically conductive materials; an intermediate frame of transparent nonconducting material free of electrically conductive materials; a second optical window disposed on the intermediate frame and including transparent nonconducting material free of electrically conductive materials to minimize distortion of radiofrequency fields by the windows and frame; and a cell aperture, wherein the atomic vapor cell is hermetically sealed by bonding between the first optical window and the second optical window to the intermediate frame.

Abstract: The present invention relates to a system that can to capture, retain, and release a small UAV/drone. Exemplary embodiments include a plurality of capture mechanisms each include a capture arm coupled to an actuator. The capture mechanism can include two pivot points, one of which can move along a track or groove, to allow the capture arm to extend and retract while maintaining a small combined circumference during UAV landing while still being able to extend to engage with a retention ring on the UAV.