Patents Assigned to United Therapeutics Corp.
  • Use of iminosugar derivatives to inhibit ion channel activity
    Publication number: 20040110795
    Abstract: Disclosed are methods to treat HCV infection by administering an iminosugar derivative compound that is effective to inhibit the activity of HCV p7 protein, and methods by which to screen for compounds that inhibit the activity of p7 protein or variants thereof. The disclosed N-substituted imino compounds, and pharmaceutical compositions thereof, inhibit the capacity of HCV p7 to permeabilize membranes.
    Type: Application
    Filed: September 23, 2003
    Publication date: June 10, 2004
    Applicant: United Therapeutics Corp.
    Inventors: Nicole Zitzmann, Raymond Allen Dwek Frs