Patents Assigned to Univ. of British Columbia
  • Patent number: 7785886
    Abstract: The invention features ABC1 nucleic acids and polypeptides for the diagnosis and treatment of abnormal cholesterol regulation. The invention also features methods for identifying compounds for modulating cholesterol levels in an animal (e.g., a human).
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: August 31, 2010
    Assignees: Xenon Pharmaceuticals, Inc., Univ. of British Columbia
    Inventors: Michael R. Hayden, Angela R. Brooks-Wilson, Simon N. Pimstone
  • Patent number: 6368599
    Abstract: The present invention provides immunogenic compositions and methods for inducing enhanced immune responses using an antigen by use of an adjuvant comprising a member selected from a Caulobacter (in particular, C. crescentus) LPS or a fragment or derivative thereof.
    Type: Grant
    Filed: February 22, 2000
    Date of Patent: April 9, 2002
    Assignee: Univ. of British Columbia
    Inventors: Solomon Langermann, Scott Koenig, John Smit, Nilofer Qureshi
  • Patent number: 6048715
    Abstract: A two-phase partition system is provided for affinity separation of a composition containing a polysaccharide binding peptide from a mixture such as a fermentation broth. The peptide may be from an enzyme and lacking in polysaccharidase activity such as the binding domain of cellulase that binds to cellulose. The system contains a phase-forming oligosaccharide polymer such as a cellulose derivative to which the peptide binds with a Ka of 10.sup.3 M to 10.sup.7 M, and a phase inducing agent such as a polyethylene glycol polymer, or a salt present at sufficiently high concentration to induce phase separation. If the oligosaccharide polymer is thermoseparating, phase separation can be induced by heating. Using the system involves contacting a composition containing the peptide such as a fusion protein with the system, partitioning the composition into a phase containing the oligosaccharide polymer by binding to the polymer and recovering the polymer containing the bound composition.
    Type: Grant
    Filed: July 24, 1996
    Date of Patent: April 11, 2000
    Assignee: Univ. of British Columbia
    Inventors: Charles A. Haynes, Peter Tomme, Douglas G. Kilburn
  • Patent number: 4944689
    Abstract: A molded connector box for connecting electric power delivery wires to a panel (radiant heating) is formed with side walls and a bottom wall. A power wire inlet slot is formed through one side wall and an outlet slot through another side wall. Each slot has a power wire clamping fixture associated therewith. Blade type wire connectors are positioned adjacent to the inlet and outlet openings and a cooperating wire securing element is connected to its adjacent side wall via a strap in a position to be folded into the box and lock into its respective wire connector to hold the wires in the connector. A cover plate snaps into position to close the connector box.
    Type: Grant
    Filed: July 13, 1989
    Date of Patent: July 31, 1990
    Assignee: Univ. of British Columbia
    Inventor: Owen R. Carr