Abstract: The present invention provides a rapid and efficient method for the preparation and isolation of biologically active polysaccharides from Aloe. The present invention includes the activated mixture of polysaccharides (referred to herein as “Immuno-10”), produced by the methods of the invention. The invention also includes the use of the polysaccharides as immunostimulating, immunomodulating and wound healing agents. The resulting immunomodulatory complex has a higher activity and is more stable than bulk carbohydrates isolated using prior art alcohol precipitation schemes.

Abstract: The present invention provides a novel vehicle for the delivery of biologically active agents. The vehicle, Maxcell™, is formulated from a novel combination of natural plant extracts and is comprised of Aloe vera polysaccharide fraction Immuno-10, cAMP, piperine, calcium phosphate and glycyrrhizinic acid.

Abstract: The present invention provides a novel vehicle for the delivery of biologically active agents. The vehicle, Maxcell™, is formulated from a novel combination of natural plant extracts and is comprised of Aloe vera polysaccharide fraction Immuno-10, cAMP, piperine, calcium phosphate and glycyrrhizinic acid.

Abstract: The present invention provides an improved method for using the measurement of total urinary 17 KS-S, referred to herein as the urinary Anabolic/Catabolic Index (ACI), as part of a biomarker for biological age.

Abstract: The present invention provides a rapid and efficient method for the preparation and isolation of biologically active polysaccharides from Aloe. The present invention includes the activated mixture of polysaccharides (referred to herein as “Inmuno-10”), produced by the methods of the invention. The invention also includes the use of the polysaccharides as immunostimulating, immunomodulating and wound healing agents. The resulting immunomodulatory complex has a higher activity and is more stable than bulk carbohydrates isolated using prior art alcohol precipitation schemes.

Abstract: The present invention provides a method for the prevention and treatment of chronic venous insufficiency. Specifically, the present invention provides a method for the prevention and treatment of varicose veins, particularly hemorrhoids by application of an effective amount of an isoquinoline alkaloid. Included in this invention is an improved method for isolating and purifying alkaloids, particularly isoquinoline alkaloids from plants.

Abstract: The present invention provides a rapid and efficient method for the preparation and isolation of biologically active polysaccharides from Aloe. The present invention includes the activated mixture of polysaccharides (referred to herein as "Immuno-10"), produced by the methods of the invention. The invention also includes the use of the polysaccharides as immunostimulating, immunomodulating and wound healing agents. The resulting immunomodulatory complex has a higher activity and is more stable than bulk carbohydrates isolated using prior art alcohol precipitation schemes.

Abstract: The present invention discloses aqueous compositions comprising liposomes of phospholipids, and at least one competitive inhibitor of an enzyme for the synthesis of melanin, in combination with at least one non-competitive inhibitor of an enzyme for the synthesis of melanin. The invention also includes the use of the compositions of this invention for the de-pigmentation of skin.

Abstract: The present invention discloses a method for the synthesis of derivatives of aloesin, alkylated at the C-7 hydroxyl group. The present invention includes the modified aloesins produced by the method of this invention and the use of these compounds as skin whitening agents.

Abstract: The present invention provides a method for the detection of species of Aloe using the polymerase chain reaction. The present invention also provides a method of differentiating between different species of Aloe using the polymerase chain reaction.

Abstract: Methods are herein provided for the isolation and purification of zeamatin, an antifungal protein from corn. The subject methods use capture chromatography and reverse phase chromatography. The methods herein described is superior to prior art techniques as it the eliminates ammonium sulfate precipitation and centrifugation steps.

Abstract: A composition of matter comprising at least 15% by weight of the compound: 8-C-.beta.-D-[2'-.omicron.-(E)-cinnamoyl]glycopyranosyl-2-[(S)-2-hydroxyl] propyl-7-methoxy-5-methylchromone. This compound, found in very small amounts in leaves of the Aloe Barbadensis plant, when concentrated to the desired level, exhibits anti-inflammatory activity.

Abstract: The present invention discloses a two-step method for the preparation of 8-C-.beta.-D-?2'-O-(E)-cinnamoyl!glycopyranosyl-2-?2-hydroxy!propyl-7-meth oxy-5-methylchromone (the "540 compound) from the readily available 5-methylchromone, Aloesin.

Abstract: The present invention provides a method for using Aloe vera as a biological vehicle for the delivery of drugs. In one embodiment Aloe vera is used as a biological vehicle to deliver the estrogen, .beta.-estradiol and the androgen, testosterone propionate. The present invention also provides a method of treating symptoms and diseases mediated by hormonal deficiencies or amenable to treatment by hormones using Aloe vera as a biological vehicle.

Abstract: The present invention provides a process for purifying the cinnamoyl-C-glycoside, 8-C-&bgr;-D-[2-O-(E)-cinnamoyl]glycopyranosyl-2- [(R)-2-hydroxy]propyl-7-methoxy-5-methyl-chromone. 8-C-&bgr;-D-[2′-O- (E)-cinnamoyl]glycopyranosyl-2-[(S) -2-hydroxy]propyl-7-methoxy-5-methylchromone, referred to herein as the “540 compound.” In one embodiment of the present invention the 540 compound is purified by extraction from a decolorizing agent with an organic solvent. The extracted product can be purified by high pressure liquid chromatography. In a second embodiment crude 540 compound, which has not been treated with a decolorizing agent, is purified by passage over neutral alumina or sephadex.