Abstract: The invention provides a drug conjugate comprising: 1) a therapeutic agent that comprises a phosphate, phosphonate, carboxy, or phosphoramidate group, and 2) a fluorescent group linked to the phosphate, phosphonate, carboxy, or phosphoramidate group to form the corresponding ester and salts thereof. The conjugates are useful for therapy and as probes.
Type:
Application
Filed:
July 14, 2016
Publication date:
July 26, 2018
Applicants:
UNIVERSITY OF IOWA RESEARCH FOUNDATION, UNIVERISTY OF CONNECTICUT
Inventors:
David F. Wiemer, Rocky J. Barney, Andrew Wiemer
Abstract: Metallothioneins are stress inducible proteins with modulating functions during inflammation. Antagonizing metallothioneins during gut inflammation reduces markers of inflammations and enhances recuperation of intestinal inflammation.
Type:
Application
Filed:
July 9, 2012
Publication date:
May 22, 2014
Applicant:
Univeristy of Connecticut
Inventors:
Martine De Vos, Debby Laukens, Lindsey Devisscher, Michael A. Lynes
Abstract: The present invention provides a system and method for passive thermal-fluids management in a liquid feed fuel cell. In particular, the present invention provides a system and method for passive thermal-fluids management in a direct methanol fuel cell having a methanol storage medium and a methanol and water mixing medium. The fuel cell may also include a methanol distribution medium that facilitates uniform distribution of methanol to the mixing medium and the anode, wherein the methanol and water are used for fuel by the direct methanol fuel cell.
Abstract: Disclosed is a method for cracking a hydrocarbon material. The method includes introducing a stream including a hydrocarbon fluid and a carrier fluid into a reaction zone. A microwave discharge plasma is continuously maintained within the reaction zone, and in the presence of the hydrocarbon fluid and the carrier fluid. Reaction products of the microwave discharge are collected downstream of the reaction zone.