Patents Assigned to Universal Bio Research Co., Ltd.
  • Patent number: 11656179
    Abstract: An optical measurement device is provided. The device includes first and second optical fibers; first and second reaction vessels, and a light guide stage coupled to the first and second optical fibers. The light guide stage is driven to simultaneously optically connect the first and second optical fibers with the first and second reaction vessels. The device includes a measurement device for receiving emissions from the first and second reaction vessels, and a connecting end arranging body that supports the first and second optical fibers along a path. The arranging body is driven along the path between a first position, in which the first optical fiber is optically connected with the measurement device so that light is transmittable from the first reaction vessel, and a second position, in which the second optical fiber is optically connected with the measurement device so that light is transmittable from the second reaction vessel.
    Type: Grant
    Filed: July 20, 2021
    Date of Patent: May 23, 2023
    Assignee: UNIVERSAL BIO RESEARCH CO., LTD.
    Inventor: Hideji Tajima
  • Patent number: 11498064
    Abstract: A photometric dispensing nozzle unit, a photometric dispensing apparatus, and a photometric dispensing method are for preventing an increase in apparatus scale and have a simple structure to be easily handled. A nozzle performs suction/discharge of gas through a distal end opening and can have a dispensing tip attached thereto. A light guide end portion is provided in the nozzle and can receive or irradiate light at a distal end of the nozzle. A dispensing cylinder has a cylinder having a cavity therein, a plunger that is slidable in the cavity, and a suction/discharge port that performs suction/discharge of gas. A suction/discharge flow path passes through the nozzle and communicates with the suction/discharge port and the distal end opening of the nozzle. A light guide path is optically connected to the light guide end portion through the nozzle but not through the dispensing cylinder.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: November 15, 2022
    Assignee: Universal Bio Research Co., Ltd.
    Inventors: Hideji Tajima, Kazuhiro Nakamura, Yu Sugiyama
  • Patent number: 11491478
    Abstract: A dispensing cylinder capable of performing a dispensing treatment for both minute and large amounts of liquid includes: a cylinder having a cavity; a nozzle provided at one end of the cylinder, having a through hole in fluid communication with the cavity and extending in an axial direction of the cavity, and a plunger slidable in the cavity in the axial direction. The cavity has a large diameter region having a large inner peripheral surface and a small diameter region having a second inner peripheral surface. The plunger has a thick shaft portion slidable in the large diameter region and a thin shaft portion protruding from a distal end of the thick shaft portion in the axial direction and slidable in the small diameter region.
    Type: Grant
    Filed: August 18, 2017
    Date of Patent: November 8, 2022
    Assignee: UNIVERSAL BIO RESEARCH Co., Ltd.
    Inventors: Hideji Tajima, Kazuhiro Nakamura, Yu Sugiyama
  • Patent number: 11376598
    Abstract: A cartridge 100 for nucleic acid detection is provided with: a first member 110 having multiple nucleic acid extraction wells; a second member 120 having a nucleic acid amplification and determination well for amplification of a nucleic acid and detection of the amplified nucleic acid; and multiple reagent containers 130. The multiple reagent containers 130 are fixed between the first member 110 and the second member 120.
    Type: Grant
    Filed: May 10, 2018
    Date of Patent: July 5, 2022
    Assignee: UNIVERSAL BIO RESEARCH CO., LTD.
    Inventor: Hideji Tajima
  • Patent number: 11332704
    Abstract: This culture device comprises: a culture container which houses cells, magnetic particles and a culture medium; a temperature adjustment unit for adjusting the temperature of the culture container; a magnet which is provided to the outside of the culture container; a magnetic force adjustment unit for adjusting the magnetic force of the magnet; and a control unit for controlling the operation of the magnetic force adjustment unit. The magnetic force adjustment unit adjusts the magnetic force of the magnet, thereby holding magnetic particles and cells in a predetermined region within the culture container, or dispersing the magnetic particles and cells within the culture container.
    Type: Grant
    Filed: July 8, 2014
    Date of Patent: May 17, 2022
    Assignee: UNIVERSAL BIO RESEARCH CO., LTD.
    Inventors: Hideji Tajima, Tetsuya Ueda
  • Patent number: 11313871
    Abstract: The specimen treatment and measurement system 2000 according to the present invention is provided with: a movement stage 2300 having a plurality of treatment lanes for treating specimens in parallel; a consumables supply module 2100 for storing consumables for use in treatment of the specimens, and supplying the consumables to the movement stage 2300; a cartridge supply module 2500 for storing cartridges for use in treatment of the specimens, and supplying the cartridges to the movement stage 2300; and a stage transfer mechanism 2400 for transferring the movement stage 2400 to each module. The cartridge supply module 2500 has a plurality of cartridge cartons for accommodating the cartridges stacked on top of each other, and a push-out mechanism for pushing cartridges out of a cartridge carton to a supply position of the cartridge supply module 2500.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: April 26, 2022
    Assignee: UNIVERSAL BIO RESEARCH CO., LTD.
    Inventor: Hideji Tajima
  • Patent number: 11204358
    Abstract: A specimen treating and measuring system according to the present invention comprises: a treatment part having a plurality of lanes for carrying out parallel processing of a plurality of specimens, and mounting cartridges in each of the plurality of lanes; a cartridge storing unit storing a plurality of types of cartridge to be used for different processes corresponding to the plurality of specimens; a sample storing unit storing and conveying sample tubes containing the plurality of specimens; a pickup unit transferring each of the plurality of types of cartridge to each lane, and transferring each of the plurality of specimens from the sample tubes to each of the plurality of lanes; and a control unit controlling the transfer of the plurality of types of cartridge and the transfer of the plurality of specimens, performed by the pickup unit.
    Type: Grant
    Filed: May 25, 2017
    Date of Patent: December 21, 2021
    Assignee: UNIVERSAL BIO RESEARCH CO., LTD.
    Inventor: Hideji Tajima
  • Publication number: 20210349024
    Abstract: An optical measurement device is provided. The device includes first and second optical fibers; first and second reaction vessels, and a light guide stage coupled to the first and second optical fibers. The light guide stage is driven to simultaneously optically connect the first and second optical fibers with the first and second reaction vessels. The device includes a measurement device for receiving emissions from the first and second reaction vessels, and a connecting end arranging body that supports the first and second optical fibers along a path. The arranging body is driven along the path between a first position, in which the first optical fiber is optically connected with the measurement device so that light is transmittable from the first reaction vessel, and a second position, in which the second optical fiber is optically connected with the measurement device so that light is transmittable from the second reaction vessel.
    Type: Application
    Filed: July 20, 2021
    Publication date: November 11, 2021
    Applicant: UNIVERSAL BIO RESEARCH CO., LTD.
    Inventor: Hideji Tajima
  • Patent number: 11099132
    Abstract: The invention relates to an optical measurement device for a reaction vessel, and a method therefor. An object is to measure the optical state within a reaction vessel in an efficient, rapid, and highly reliable manner, without an expansion of the device scale.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: August 24, 2021
    Assignee: UNIVERSAL BIO RESEARCH CO., LTD.
    Inventor: Hideji Tajima
  • Publication number: 20210106985
    Abstract: A photometric dispensing nozzle unit, a photometric dispensing apparatus, and a photometric dispensing method are for preventing an increase in apparatus scale and have a simple structure to be easily handled. A nozzle performs suction/discharge of gas through a distal end opening and can have a dispensing tip attached thereto. A light guide end portion is provided in the nozzle and can receive or irradiate light at a distal end of the nozzle. A dispensing cylinder has a cylinder having a cavity therein, a plunger that is slidable in the cavity, and a suction/discharge port that performs suction/discharge of gas. A suction/discharge flow path passes through the nozzle and communicates with the suction/discharge port and the distal end opening of the nozzle. A light guide path is optically connected to the light guide end portion through the nozzle but not through the dispensing cylinder.
    Type: Application
    Filed: March 28, 2018
    Publication date: April 15, 2021
    Applicant: Universal Bio Research Co., Ltd.
    Inventors: Hideji Tajima, Kazuhiro Nakamura, Yu Sugiyama
  • Patent number: 10976253
    Abstract: A highly-reliable absorbance measuring device that enables highly-accurate measurement of absorbance, and a method thereof are provided. A liquid containing unit that can contain a chemical substance solution to be measured, a nozzle that communicates with a suction/discharge mechanism that sucks/discharges gas, a flow tube that includes a mouth part, which can be inserted into the liquid containing unit, at a lower end and that is detachably attached to the nozzle at an upper end, an emitting end that can emit measurement light, a light receiving end that can receive the light emitted from the emitting end, and a control unit are included. The control unit is configured to suck a prescribed amount of the chemical substance solution into the flow tube, and to lead absorbance on the basis of intensity of transmitted light acquired by emission of measurement light in a vertical direction into the flow tube.
    Type: Grant
    Filed: December 14, 2016
    Date of Patent: April 13, 2021
    Assignee: UNIVERSAL BIO RESEARCH CO., LTD.
    Inventors: Hideji Tajima, Takaki Sugimoto, Tetsuya Ueda
  • Patent number: 10883926
    Abstract: A general-purpose optical measuring device enables at least measurement of a nucleic acid amplification amount; detection or quantitative measurement by a nucleic acid detection method, an immunoassay method, an enzyme method; or measurement of concentration or absorbance, and a method of the same. There are included a photometric content designation unit, an irradiation reception pair including an emission end that can emit measurement light, and a reception end that can receive light from the emission end, a photometric container that can store measurement target chemical substance solution, and includes a bottom portion having a formed translucent region, a nozzle communicated with a suction discharge mechanism of gas, a flow tube, an optical measurement unit, and a control unit configured to suck and hold the chemical substance solution into the flow tube, or store the chemical substance solution into the photometric container.
    Type: Grant
    Filed: April 7, 2017
    Date of Patent: January 5, 2021
    Assignee: UNIVERSAL BIO RESEARCH CO., LTD.
    Inventor: Hideji Tajima
  • Patent number: 10837907
    Abstract: A multiple reaction parallel measurement apparatus is intended to measure a large number of reactions quickly, simply and with high accuracy. The apparatus includes: a plurality of light guiding paths corresponding to a plurality of reaction spot array elements, including a measuring end able to be in proximity of or in contact with each one of the reaction spots, and arranged to guide light generated by a reaction at the reaction spot to a connecting end; a measurement head arranged such that the measuring ends reach all together predetermined measurement positions of the corresponding reaction spots of the reaction spot array elements at a predetermined scan period; a light guiding path selector including a light guiding region optically connected to the connecting end; a light receiving unit; and a digital data converter to obtain digital data by converting image region data obtained from the light receiving unit.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: November 17, 2020
    Assignee: Universal Bio Research Co., Ltd.
    Inventor: Hideji Tajima
  • Patent number: 10837011
    Abstract: In a method of nucleic acid extraction using a support, the present invention realizes collection of a nucleic acid from a liquid containing the nucleic acid at an extremely low concentration at which collection cannot be achieved with polyacrylamide. A method of extracting a nucleic acid, comprising allowing the nucleic acid to be adsorbed onto a support in the presence of a chaotropic salt and an alcohol in coexistence with an anionic polymer. A reagent for nucleic acid extraction, comprising an anionic polymer, a chaotropic salt, an alcohol and a support.
    Type: Grant
    Filed: March 18, 2015
    Date of Patent: November 17, 2020
    Assignee: UNIVERSAL BIO RESEARCH CO., LTD.
    Inventors: Ryouji Karinaga, Tetsuya Ueda, Hideji Tajima
  • Patent number: 10822646
    Abstract: A reaction container control system including a reaction container, a sealing lid, a temperature control block, and a heater. The reaction container includes a lower side wall section, an upper side wall section, and an aperture. The sealing lid seals the reaction container by fitting to the aperture of the reaction container. When the sealing lid is fitted to the aperture, light based on an optical state within the reaction container is receivable by a measuring device via the sealing lid. The temperature control block contacts or extends adjacent the lower side wall section, and includes a temperature source operable to increase or decrease a temperature inside the reaction container. The heater contacts or extends adjacent the upper side wall section, and includes a heat source operable to heat the reaction container to prevent condensation on the sealing lid fitted to the aperture.
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: November 3, 2020
    Assignee: Universal Bio Research Co., Ltd.
    Inventor: Hideji Tajima
  • Patent number: 10775397
    Abstract: An apparatus and related method to reliably prevent cross-contamination and to decrease working time or space involved with reaction treatment. The apparatus includes: a container group having one or more reaction containers and two or more liquid storage portions arranged in a linear shape; a dispensing head to which one or more dispensing tips insertable into the container group are detachably attached, the dispensing head being relatively movable with respect to the container group in a linear direction; a magnetic portion provided in the dispensing head and capable of: applying a magnetic field into each dispensing tip so that the magnetic particles are adsorbed to an inner wall of the dispensing tip, and removing the magnetic field so that the magnetic particles are resuspended in a solution; and an ultrasonic vibration device which applies ultrasonic vibration to a sample storage portion including at least one of the liquid storage portions.
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: September 15, 2020
    Assignee: Universal Bio Research Co., Ltd.
    Inventor: Hideji Tajima
  • Publication number: 20200209268
    Abstract: A specimen treating and measuring system according to the present invention comprises: a treatment part having a plurality of lanes for carrying out parallel processing of a plurality of specimens, and mounting cartridges in each of the plurality of lanes; a cartridge storing unit storing a plurality of types of cartridge to be used for different processes corresponding to the plurality of specimens; a sample storing unit storing and conveying sample tubes containing the plurality of specimens; a pickup unit transferring each of the plurality of types of cartridge to each lane, and transferring each of the plurality of specimens from the sample tubes to each of the plurality of lanes; and a control unit controlling the transfer of the plurality of types of cartridge and the transfer of the plurality of specimens, performed by the pickup unit.
    Type: Application
    Filed: May 25, 2017
    Publication date: July 2, 2020
    Applicant: UNIVERSAL BIO RESEARCH CO., LTD.
    Inventor: Hideji TAJIMA
  • Patent number: 10676707
    Abstract: A culture system comprises: a preparatory culture vessel and a main culture vessel that accommodate cells and a solution; a main stage that holds the preparatory culture vessel and the main culture vessel; a connecting tube that connects the culture vessels; a valve that opens and closes the connecting tube; and a rotating mechanism that rotates the main stage and imparts a height difference between the culture vessels to transfer the cells and solution by dropping between the culture vessels.
    Type: Grant
    Filed: September 2, 2014
    Date of Patent: June 9, 2020
    Assignee: Universal Bio Research Co., Ltd.
    Inventor: Hideji Tajima
  • Patent number: 10656111
    Abstract: A device for electrical measurement of a target chemical substance includes: an electrode array element including a base, an electrode array section in which electrodes which are disposed on the base and to each of which a test substance is fixed or can be fixed are arrayed, and a terminal array section in which terminals disposed on the base so as to correspond to the electrodes and electrically connected to the electrodes are arrayed; a processing head having an electrode array element support section supporting the electrode array element detachably to make electrical connection to the terminals possible; a container group including a liquid storing section and a measurement container; a support section moving mechanism; and a measurement section capable of measuring a signal generated by applying a predetermined voltage to a test substance fixed to each of the electrodes in the measurement container.
    Type: Grant
    Filed: July 7, 2016
    Date of Patent: May 19, 2020
    Assignee: Universal Bio Research Co., Ltd.
    Inventor: Hideji Tajima
  • Patent number: 10625255
    Abstract: The present invention relates to a soft stopper penetrating dispensing device and a soft stopper penetrating dispensing method. A purpose of the present invention is to suction and discharge liquid with respect to a soft stopper sealed container sealed with a soft stopper such as a rubber stopper without removing the soft stopper. The soft stopper penetrating dispensing device includes a dispensation available punching head which is provided to be relatively movable relative to a stage where the soft stopper sealed container sealed with the soft stopper is able to be placed, a punching tip which has a through-hole along the vertical direction and is made of a hard material and formed in a tapered shape, a dispensing needle tip which is movably provided relative to the head by the dispensing moving mechanism provided in the dispensation available punching head and is able to suction and discharge the liquid.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: April 21, 2020
    Assignee: Universal Bio Research Co., Ltd.
    Inventor: Hideji Tajima