Abstract: A lateral semiconductor device has a semiconductor layer on an insulating layer on a semiconductor substrate. The semiconductor layer has a region of a first conduction type and a region of a second conduction type with a drift region therebetween. The drift region is provided by a region of the first conduction type and a region of the second conduction type. The first and second conduction type drift regions are so arranged that when a reverse voltage bias is applied across the first and second conduction type regions of the semiconductor layer, the second conduction type drift region has an excess of charge relative to the first conduction type drift region which varies substantially linearly from the end of the drift region towards the first conduction type region of the semiconductor layer to the end of the drift region towards the second conduction type region of the semiconductor layer.

Abstract: A humanized antibody or antibody fragment having all or part of the CDRs as defined and capable of binding to the human CD18 antigen. The antibody and fragment may be labeled and are useful in a variety of applications, such as in therapy in treating leukocyte mediated conditions such as inhibiting ingress of leukocytes into the lung and other organs and treatment of inflammation. Also provided is a kit for detecting the presence of human CD18 antigen comprising an antibody or fragment of the invention, which is optionally labeled.

Abstract: A method for the production of a holographic sensor wherein the holographic recording material forming the sensitive element is a polymer matrix, which comprises diffusing into the matrix one or more soluble salts that undergo reaction in situ to form an insoluble sensitive precipitate; and recording a holographic image. This method allows the production of a holographic sensor wherein the holographic recording material forming the sensitive element is an insoluble polymer film.

Abstract: There is provided a human myeloma cell tine for use in a method for producing a human monoclonal antibody.

Abstract: A light emitting device formed of a substrate having first and second regions, a first non-transparent electrode formed on the substrate in the first region, a layer of organic light emitting material provided over the first non-transparent electrode in the first region, a layer of organic light emitting material provided over the substrate in the second region, the light emitting materials each having at least one planar surface which is corrugated, a second non-transparent electrode formed over the light emitting material in the first region, and a mirror formed over the light emitting material in the second region. A device having a stacked structure of electrodes and light emitting layers is also disclosed, as are various methods of fabricating the devices.

Abstract: A process is provided for modifying growth or architecture of plants by altering the level or the functional level of a cell division controlling protein, preferably a cell-division controlling protein that binds or phosphorylates retinoblasoma-like proteins, more preferably a cyclin, particularly a D-type cyclin within cells of a plant. Also provided are chimeric genes comprising a transcribed DNA region encoding an RNA or a protein, which when expressed either increases or decreases the level or functional level of a cell-division controlling protein, and plant cells and plants expressing such chimeric genes.

Abstract: Disclosed is a method of altering one or more characteristics of at least some of the cells of the reproductive tract of a mammalian individual by the introduction into said cells of a nucleic acid, together with a composition comprising nucleic acid, for use in the method.

Abstract: A memory element comprising nanomagnets having a rotational symmetry selected in order to provide high remanence and a suitable coercivity. There is also a sensor element comprising nanomagnets having a rotational symmetry selected such that they are superparamagnetic and exhibit substantially zero hysteresis so that a magnetisation of the nanomagnets depends only on the current value of applied field and not on the field history.

Abstract: The present invention relates to isolated or purified molecule(s) capable of binding to one or more of telomeric, G-quadruplex, or G-quartet nucleic acid(s).

Abstract: A holographic filter for an optical communication system is configurable to provide signal power equalisation for a number of optical signals or signal channels in a wavelength division multiplexed system.

Abstract: A process is provided for modifying growth or architecture of plants by altering the level or the functional level of a cell division controlling protein, preferably a cell-division controlling protein that binds phosphorylates retinoblasoma-link proteins, more preferably a cyclin, particularly a D-type cyclin within cells of a plant. Also provided are chimeric genes comprising a transcribed DNA region encoding an RNA or a protein, which when expressed either increases or decreases the level or functional level of a cell-division controlling protein, and plant cells and plants expressing such chimeric genes.

Abstract: A sandwich material comprising two metal plates affixed to and separated by a fibrous core, is characterised in that the core comprises a three-dimensional porous network comprising metal fibres, wherein substantially all of the fibres are inclined at an acute angle to the plates. The sandwich material is lightweight, thin and handles like a monolithic sheet. It displays high beam stiffness and is easy to weld. It as therefore particularly useful in the manufacture of aircraft and vehicle parts.

Abstract: A method for treating a metal comprises subjecting the metal to electrolysis in the presence of an electrolyte using alternating pulses of voltage and/or current, said alternating pulses being of opposite polarity, wherein if the electrolyte is an aqueous electrolyte it is an aqueous solution of a salt selected from the group consisting of alkali metal salts, alkali earth metal salts, aluminium salts and amnonium salts. The method is effective in improving the surface properties of the metal, such as hardness, friction and wear properties.

Abstract: A clamp for measuring an electric current flowing in conductors, the clamp comprising first and second jaws (1, 2) interconnected by a hinge axis (3) to be movable between a closed position and an open position, the jaws being provided respectively with first and second annular magnetic circuit segments (4, 5), each segment (4, 5) having a proximal end (7, 8) and a distal end (9, 10) relative to the hinge, and at least the first segment (5) being mounted to rock about a rocker axis (6) parallel to a hinge axis (3), the clamp including spacer means (12) for spacing the proximal ends (7, 8) apart, which spacer means are active at least when the distal ends (9, 10) are spaced apart by a distance that is greater than or equal to a predetermined safety distance.

Abstract: The invention provides a method of producing an immune response in a mammal to an antigen which comprises modifying said antigen by introducing an alkyl aldehyde group into said antigen and introducing said modified antigen into the mammal. Periodate or glycolaldhyde may be used as the agent to introduce the aldehyde groups.

Abstract: A holographic filter for an optical communication system is configurable to provide signal power equalisation for a number of optical signals or signal channels in a wavelength division multiplexed system.

Abstract: Disclosed is a method of altering one or more characteristics of at least some of the cells of the reproductive tract of a mammalian individual by the introduction into said cells of a nucleic acid, together with a composition comprising nucleic acid, for use in the method.

Abstract: A process for the transformation of an organic molecule catalyzed by a ligand-metal complex, is conducted in compressed CO2 as a solvent, wherein the complex comprises a perfluorinated group. Further, a process for the polymerization of a monomer containing two or more polymerizable groups, optionally together with another copolymerizable monomer, to give a cross-linked polymer in the form of essentially spherical particles, is conducted in compressed CO2 as a solvent, typically in the presence of a surfactant.

Abstract: The invention relates to the finding that animals deficient in the Peg3 gene suffer from a number of phenotypic traits, including obesity, aberrant thermoregulation and behavioral defects, including impaired maternal behavior. The invention provides a transgenic non-human animal which comprises an inactive copy for the Peg3 gene, and the use of such animals as model systems in assays for novel therapies in the treatment of conditions such as those mentioned above.

Abstract: The present invention pertains to an enzymatic reaction involving a pyridine nucleotide cofactor, wherein an enzyme is used that has a sequence of greater than 70% identity to SEQ ID NO: 2 and is capable of transferring reducing equivalents between pyridine nucleotide cofactors. Alternatively, a cell transformed to express the enzyme may be used.