Patents Assigned to Universidad de la Frontera
  • Patent number: 11649513
    Abstract: A diagnostic kit for simultaneously detecting at least seven silent sexually transmitted diseases (SSTDs) having a diagnostic strip which has detection zones with at least eight probes with SEQ ID NOs: 3, 6, 9, 12, 15, 18, 21, 24; at least 14 primers with SEQ ID NOs: 1, 2, 4, 5, 7, 8, 10, 11, 13, 14, 16, 17, 19, 20, 22, 23; an instruction manual; a nucleotide sequence set for simultaneously detecting at least seven silent sexually transmitted diseases (SSTDs); use of the kit to detect at least the following pathogens: Herpes Virus type 1, Herpes Virus type 2, Chlamydia trachomatis, Ureaplasma urealitycum, Mycoplasma hominis, Mycoplasma genitalium, and Human papillomavirus (HPV); a method for simultaneously detecting at least seven silent sexually transmitted diseases (SSTDs).
    Type: Grant
    Filed: March 3, 2017
    Date of Patent: May 16, 2023
    Assignee: UNIVERSIDAD DE LA FRONTERA
    Inventors: Raul Segundo Sanchez Gutierrez, Alejandra Pilar Andana Vargas, Carmen Gloria Ili Gangas, Doris Menzel Middelmann, Jaime Patricio Lopez Mendez, Juan Carlos Roa Strauch, Priscilla Solange Brebi Mieville
  • Patent number: 11497592
    Abstract: An in situ measuring instrument of the convergence angle (CA) of a dental preparation or stump in the field of dentistry, applied to humans or other species, having a movable bar, and a support bar arranged parallel to each other and coupled perpendicularly and slidable relative to a central bar by a first guiding hole at one end of the central bar and a second guiding hole at one end of the support bar which allow the relative vertical movement of the movable bar and horizontal movement of the support bar, allowing both bars to be adjusted to the base of the stump. This instrument allows measuring both natural and artificial teeth and implants, as well as fixed and mobile prostheses, just as if any device attached to the tooth (artificial or implant) is desired to be installed.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: November 15, 2022
    Assignee: UNIVERSIDAD DE LA FRONTERA
    Inventors: Marco Antonio Flores Velasquez, Rodolfo Gabriel Figueroa Saavedra
  • Patent number: 10723966
    Abstract: The present invention relates to a bioadditive for heavy oils that serves to reduce polluting emissions and bio-enhancer of the combustion performance for heavy oils, which comprises methyl esters of raps oil, also called raps biodiesel, in the range of up to 80% v/v, surfactants in the range of up to 80% v/v, diluents in the range of up to 20% v/v and metal oxides between 0.1-5 g/L.
    Type: Grant
    Filed: June 30, 2015
    Date of Patent: July 28, 2020
    Assignees: UNIVERSIDAD DE LA FRONTERA, MOLINERA GORBEA LIMITADA
    Inventors: Rodrigo Javier Navia Diez, Isaac Eliecer Reyes Caniupan, Tomas Guillermo Mora Chandia, Robinson Eugenio Betancourt Astete
  • Patent number: 9974301
    Abstract: This invention relates to a fungicidal composition for controlling phytopathogenic diseases, comprising a mixture of volatile compounds: 14-17% v/v ethanol, 28-33% v/v 3-methylbutanol, 18-21% v/v isobutyl acetate, 17-20% v/v isoamyl acetate, and 13-16% v/v alpha-bisabolol, relative to the total volume of the composition. The invention also relates to the use of the fungicidal composition in order to inhibit the growth of the pathogenic fungus Botrytis cinerea.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: May 22, 2018
    Assignee: UNIVERSIDAD DE LA FRONTERA
    Inventors: Andres Quiroz, Heidi Schalchli, Emilio Hormazabal
  • Patent number: 9583302
    Abstract: A piece of scientific/technological equipment is presented for the generation of a convergent photon beam for radiotherapy or other applications. This equipment consists of adequately modifying the trajectory of an electron beam from a linear accelerator (LINAC) by applying magnetic and/or electric fields. These electrons perpendicularly impact the surface of a curved material that has a particular curvature ratio (anode), thus generating X-rays. The interaction of the electrons with the atoms of the anode's material generate X-rays with a non-isotropic angular-spatial distribution, with a greater concentration in the focal direction, which is defined by the geometry of the anode. A curved collimator with an adequate curvature ratio is attached to the back of the anode. The collimator is made up of an array of a great number of small holes that point toward the focal point. This device transmits X-rays solely in the focal direction.
    Type: Grant
    Filed: April 19, 2012
    Date of Patent: February 28, 2017
    Assignees: UNIVERSIDAD DE LA FRONTERA, UNIVERSIDAD NACIONAL DE CORDOBA
    Inventors: Rodolfo Figueroa Saavedra, Mauro Valente
  • Patent number: 9464121
    Abstract: The present invention features compositions and methods for the treatment of erectile dysfunction. The compositions include substantially pure polypeptides derived from ?-latrotoxin and can include other substances, such as pharmaceutically acceptable carriers or diluents, liposomes, hydrogels, and additional active ingredients for the treatment of erectile dysfunction. Also provided are methods, including methods for using the compositions for treatment of erectile dysfunction and in the preparation of medicaments.
    Type: Grant
    Filed: December 31, 2008
    Date of Patent: October 11, 2016
    Assignees: UNIVERSIDAD DE LA FRONTERA, UNIVERSIDAD FEDERAL DE SAO PAULO, LABORATORIOS ANDROMACO S.A.
    Inventors: Fernando Gonzalo Romero Mejia, Raul Patricio Salvatici Salazar, Antonio Miranda
  • Patent number: 9005886
    Abstract: The present invention discloses a method for cryopreservation of human spermatozoa: the method comprises providing spermatozoa free from seminal liquid; mixing the spermatozoa with vitrification medium, wherein the main cryoprotectant agent is 0.1-0.3 M sucrose; placing the sample inside straws and rapidly freezing them; refrigerating the straws with no need of liquid N2; and devitrifying the sample in a medium of the present invention. The present invention furthermore discloses a portable kit that makes easy to implement the method, said kit comprising vitrification and devitrification solutions in the volumes required to develop the method and the physical support to carry out the same, i.e. the straws. The use of this kit is also disclosed for the treatment of disorders related to reproductive failures.
    Type: Grant
    Filed: February 16, 2011
    Date of Patent: April 14, 2015
    Assignees: Universidad de La Frontera, Universitaet Ulm
    Inventors: Raul Sanchez Gutierrez, Jennie Risopatron Gonzalez, Mabel Schulz Rubilar, Evgenia Isachenko, Vladimir Isachenko
  • Patent number: 8980842
    Abstract: The present invention is directed to an active agent with contraceptive properties which corresponds to a peptide fragment of the Latrodectus mirabilisi's venom. The peptide generally includes the amino acid sequence of SEQ ID NO 2 or sequences that are at least 85% similar, obtained by chemical synthesis or through recombinant DNA technologies. Furthermore, a pharmaceutical contraceptive composition comprising the peptide fragment and one or more pharmaceutically acceptable vehicles is also described. The peptide fragment and pharmaceutical compositions are useful as a contraceptive and spermicide agent.
    Type: Grant
    Filed: March 22, 2011
    Date of Patent: March 17, 2015
    Assignees: Universidad de la Frontera, Universidad de Chile, Universidad Federal de Sao Paulo, Laboratorios Andromaco S.A.
    Inventors: Fernando Romero Mejia, Raúl Sanchez Gutierrez, Eduardo Bustos Obregón, Antonio De Miranda, Andrés Rudolphy Fontaine
  • Publication number: 20140112451
    Abstract: A piece of scientific/technological equipment is presented for the generation of a convergent photon beam for radiotherapy or other applications. This equipment consists of adequately modifying the trajectory of an electron beam from a linear accelerator (LINAC) by applying magnetic and/or electric fields. These electrons perpendicularly impact the surface of a curved material that has a particular curvature ratio (anode), thus generating X-rays. The interaction of the electrons with the atoms of the anode's material generate X-rays with a non-isotropic angular-spatial distribution, with a greater concentration in the focal direction, which is defined by the geometry of the anode. A curved collimator with an adequate curvature ratio is attached to the back of the anode. The collimator is made up of an array of a great number of small holes that point toward the focal point. This device transmits X-rays solely in the focal direction.
    Type: Application
    Filed: April 19, 2012
    Publication date: April 24, 2014
    Applicants: UNIVERSIDAD NACIONAL DE CORDOBA, UNIVERSIDAD DE LA FRONTERA
    Inventors: Rodolfo Figueroa Saavedra, Mauro Valente
  • Publication number: 20130280183
    Abstract: The invention is referred to a new dentifrice composition with anticariogenic properties, which has as active anticariogenic ingredients a combination of propolis, methylparaben and propylparaben. From these 3 components, propolis is the major component, which is reinforced in its activity for a smaller amount of methylparaben and propylparaben obtaining a composition with a high anticariogenic composition without side effects. These active ingredients are present in the following percentages in relation to the total weight of the dentifrice composition: 2 a 10% of propolis; 0.01 a 0.30% of methylparaben 0.01 a 0.15% of propylparaben The dentifrice composition also includes a fluorinated compound and other auxiliary components usually used for formulation such as abrasives, moisturizing, foaming agents, thickeners, sweeteners, flavorants and demineralized water.
    Type: Application
    Filed: August 29, 2011
    Publication date: October 24, 2013
    Applicants: UNIVERSIDAD DE LA FRONTERA, KNOP LABORATORIOS LTDA, PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE
    Inventors: Luis Antonio Salazar Navarrete, Gloria Del Carmen Montenegro Rizzardinni
  • Publication number: 20130157250
    Abstract: The present invention discloses a method for cryopreservation of human spermatozoa: the method comprises providing spermatozoa free from seminal liquid; mixing the spermatozoa with vitrification medium, wherein the main cryoprotectant agent is 0.1-0.3 M sucrose; placing the sample inside straws and rapidly freezing them; refrigerating the straws with no need of liquid N2; and devitrifying the sample in a medium of the present invention. The present invention furthermore discloses a portable kit that makes easy to implement the method, said kit comprising vitrification and devitrification solutions in the volumes required to develop the method and the physical support to carry out the same, i.e. the straws. The use of this kit is also disclosed for the treatment of disorders related to reproductive failures.
    Type: Application
    Filed: February 16, 2011
    Publication date: June 20, 2013
    Applicants: UNIVERSITAET ULM, UNIVERSIDAD DE LA FRONTERA
    Inventors: Raul Sanchez Gutierrez, Jennie Risopatron Gonzalez, Mabel Schulz Rubilar, Evgenia Isachenko, Vladimir Isachenko
  • Patent number: 8070482
    Abstract: A system of detection and analysis of gas or fuel oil flames using optical devices, consisting of a sensor that targets the flame's reaction zone through an optical access, a processing and control module, and an actuator, responsible for controlling the damper. The system optimizes combustion equipment operation by controlling the damper, obtaining better performance and reducing polluting emissions.
    Type: Grant
    Filed: June 16, 2008
    Date of Patent: December 6, 2011
    Assignees: Universidad de Concepción, Universidad de la Frontera, ANWO S.A
    Inventors: Oscar Francisco Farias Fuentes, Daniel Gerónimo Sbarbaro Hofer, Robinson Eugenio Betancourt Astete
  • Publication number: 20110237523
    Abstract: The present invention is directed to an active agent with contraceptive properties. Said active agent corresponds to a molecular fraction of the venom from the spider Latrodectus mirabilis. The active agent is a peptide with a sequence according to SEQ ID NO 1 or sequences that are at least 85% similar, obtained by chemical synthesis or through recombinant DNA technologies. In a preferred embodiment, the active agent with contraceptive properties is a peptide with 10 to 30 amino acids, preferably 20 amino acids. Said embodiment is exemplified by the sequence identified as SEQ ID NO 2 or sequences that are at least 85% similar, obtained by chemical synthesis or through recombinant DNA technologies. Furthermore, a method to obtain the contraceptive peptide is disclosed, said method comprising cloning the nucleotide sequence in a microorganism.
    Type: Application
    Filed: March 22, 2011
    Publication date: September 29, 2011
    Applicants: Universidad de la Frontera, Universidad de Chile, Universidad Federal de Sao Paulo, Laboratorios Andromaco S.A.
    Inventors: Fernando Romero Mejia, Raúl Sanchez Gutierrez, Eduardo Bustos Obregón, Antonio De Miranda, Andrés Rudolphy Fontaine
  • Patent number: 7622109
    Abstract: A novel gene isolated from Deschampsia antarctica coding for a lipase like protein is disclosed. A system for production of recombinant enzyme is also disclosed as well as use for the enzyme in sunscreen.
    Type: Grant
    Filed: December 18, 2008
    Date of Patent: November 24, 2009
    Assignees: Vitrogen SA, Universidad de la Frontera
    Inventors: Manuel Gidekel, Ana Gutierrez, Claudia Rabert, Gustavo Gabrera, Jaime Sanchez, Leon Bravo
  • Publication number: 20080253977
    Abstract: A novel gene isolated from Deschampsia antarctica coding for a lipase like protein is disclosed. A system for production of recombinant enzyme is also disclosed as well as uses for the enzyme.
    Type: Application
    Filed: April 16, 2007
    Publication date: October 16, 2008
    Applicants: Vitrogen SA, Universidad de la Frontera, Universidad de Concepcion
    Inventors: Manuel Gidekel, Ana Gutierrez, Claudia Rabert, Gustavo Gabrera, Jaime Sanchez, Leon Bravo