Abstract: The invention relates to self-assembled nanofibers of chitosan and bioactive compounds for use as nutraceuticals or drugs. Suitable bioactive compounds include molecules of a low molecular size with acid or lactone groups, aromatic rings and hydroxyls. The nanofibers are absorbed, without degradation, in the small intestine, containing and protecting the bioactive compounds until they reach target organs. The nanofibers also cross the blood-brain barrier, allowing the compounds to reach the brain where they act as a controlled release system. If the bioactive compounds are neuroprotectors, the nanofibers can treat or prevent neurodegenerative diseases, strokes and other diseases related to aging or associated with oxidative stress. The invention also relates to a method for obtaining the nanofibers involving mixing chitosan with the bioactive compounds and allowing self-assembly. The invention further relates to a dosage form containing the nanofibers, particularly for oral administration.

Abstract: The invention discloses a bacterial strain of non pathogenic Cobetia marina useful in aquaculture, corresponding to an isolated Cobetia marina strain, Gram negative, oxidase positive, deposited under registry number CECT N°7764; grows with dibenzothiophene (DBT) as the only carbon source. Also disclosed is a method to obtain a biosurfactant surfactant extract comprising growing strain Cobetia marina (MM1IDA2H-1) CECT N° 7764 in a reactor with liquid growth medium from 24 to 48 hours at a temperature between 10 and 35° C., pH 6 to 8; constant stirring between 100 to 400 rpm and oxygen saturation between 10 to 21%; until obtaining a grown cell culture and extracellular products plus inorganic salts; separating the cells, lyophilizing supernatant, sieve the obtained powder and dry.

Abstract: The present invention refers to an Integrated Implant System constituted as a gel-matrix-cells integrated system, that allows providing implants in a brief time period, for covering a great skin extension to be treated, with a successful acceptance in patients with burns, chronic damage or wound skin, needing of a skin grafting.

Abstract: The invention discloses a bacterial strain of non pathogenic Cobetia marina useful in aquaculture, corresponding to an isolated Cobetia marina strain, Gram negative, oxidase positive, deposited under registry number CECT N° 7764; grows with dibenzothiophene (DBT) as the only carbon source. Also disclosed is a method to obtain a biosurfactant surfactant extract comprising growing strain Cobetia marina (MM1IDA2H-1) CECT N° 7764 in a reactor with liquid growth medium from 24 to 48 hours at a temperature between 10 and 35° C., pH 6 to 8; constant stirring between 100 to 400 rpm and oxygen saturation between 10 to 21%; until obtaining a grown cell culture and extracellular products plus inorganic salts; separating the cells, lyophilizing supernatant, sieve the obtained powder and dry.