Patents Assigned to UNIVERSIDAD DEL VALLE
  • Patent number: 11696973
    Abstract: This invention discloses an implant for regeneration of tissue with lesions, comprising a mixture with different types of cells, particularly, mesenchymal stem cells (MSC), endothelial cells, and specific functional cells according to the nature and function of the tissue, included into the biocompatible polymeric matrix, where the cells may or may not be organized in a specific way. This innovation also discloses a method to manufacture the implant. The implant of the present invention is useful for replacement or regeneration of animal and human tissues.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: July 11, 2023
    Assignees: UNIVERSIDAD DEL VALLE, UNIVERSIDAD AUTONOMA DE OCCIDENTE
    Inventors: Paola Andrea Neuta Arciniegas, Alvaro Jose Rojas Arciniegas, Jose Oscar Gutierrez Montes
  • Patent number: 11570984
    Abstract: A method for organ and tissue chimerization using bone marrow cellular treatment, which avoids rejection of transplanted organs and diminishes or suspends the use of immunosuppressant drugs in patients subjected to transplant procedures. The method comprises washing the organ in an electrolyte solution. A further step of washing the organ in a wash solution. The organ is then placed in a culture solution and incubated with bone marrow cells.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: February 7, 2023
    Assignee: Universidad del Valle
    Inventors: Jose Oscar Gutierrez Montes, Alejandra Maria Jerez Valderrama, Jaime Alfonso Muñoz Botina
  • Patent number: 10602741
    Abstract: An organ-chimerization maintenance device. The organ-chimerization device includes at least one large cannula connector that connects to at least one of an organ's vessels. The large cannula is configured to supply a chimerization solution to the organ. The organ-chimerization device also includes a an oxygenation cannula connector that facilitates oxygenation of the organ during chimerization.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: March 31, 2020
    Assignee: Universidad del Valle
    Inventors: Jose Oscar Gutierrez Montes, Alejandra Maria Jerez Valderrama, Jaime Alfonso Muñoz Botina
  • Patent number: 10603381
    Abstract: This invention relates to novel nanocompounds that are cytotoxic to tumor cells when combined with ultraviolet light, the nanocompounds comprising multilayered carbon nanotubes with anatase-phase titanium dioxide or anatase-phase titanium dioxide and folate. The invention also relates to a composition containing said nanocompounds and to a method for the treatment of cancer; comprising the administration of said composition in co-treatment with UV radiation. The invention further relates to a method for the synthesis of the nano-compounds.
    Type: Grant
    Filed: February 17, 2015
    Date of Patent: March 31, 2020
    Assignee: Universidad del Valle
    Inventors: Rubén Jesús Camargo Amado, José Oscar Gutiérrez Montes, Mónica Jimena Basante Romo, William David Criollo Gómez
  • Patent number: 10413609
    Abstract: The invention relates to an artificial bacteriophage for supplying medicaments, nutrients, proteins, DNA/RNA or other type of molecules to bacteria and/or diseased cells, directly to the cytoplasm, passing through the cell membrane thereof, through a pore of said membrane. The artificial bacteriophage is based on carbon nanostructures and comprises a nanocontainer for medicaments, a channel for transporting medicaments and a tip together with an array of linker proteins and protein receptors.
    Type: Grant
    Filed: February 17, 2015
    Date of Patent: September 17, 2019
    Assignee: Universidad del Valle
    Inventors: Jaime Velasco Medina, John Michael Espinosa Durán, Julio César Arce Clavijo
  • Patent number: 10119189
    Abstract: The present invention discloses a process for the manufacture of a thin-film multilayered coating used in treating biomedical substrates and a coating in multilayered thin-film form (S/TiN/Ti/TiZr) to treat biomedical substrates used in surgical implants.
    Type: Grant
    Filed: October 4, 2013
    Date of Patent: November 6, 2018
    Assignee: Universidad del Valle
    Inventors: Federico Sequeda Osorio, Jose Oscar Gutierrez Montes, Alexander Ruden Muñoz
  • Patent number: 9625399
    Abstract: The application relates to a device based on the electrothermal method for determining thermal conductivity, which allows the examination of various phenomena, with a high level of reliability, through the study of the thermal behavior of materials. The device is constituted by a sample-carrying cylinder surrounded by a resistance element that creates a radial heat flow in the sample, a cooling system based on a spiral-form heat exchanger incorporated into the thermal device, means for the storage of a fluid and a data-storage device. Furthermore, the present application describes the use of the device in processes for determining the productive potential of the soil (“PPS”) and the examination of the nutritional quality of agro-ecological produce and foods.
    Type: Grant
    Filed: December 1, 2009
    Date of Patent: April 18, 2017
    Assignee: UNIVERSIDAD DEL VALLE
    Inventor: Orlando Zuñiga Escobar
  • Patent number: 9474551
    Abstract: The current request reports an external fixation device to stabilize bone fractures with adaptable configuration during different stages of surgery or during treatment, through the generation of six degrees of freedom among the bone fragments. The device comprises numerous press-connector means, numerous cylindrical bars, numerous osteosynthesis screws and optionally from one to several rigid rings and one or more extension elements that permit generating diverse stable configurations to treat bone fractures.
    Type: Grant
    Filed: October 9, 2010
    Date of Patent: October 25, 2016
    Assignee: UNIVERSIDAD DEL VALLE
    Inventors: Arlex Leyton Virgen, Andres Machado Caicedo, Jaime Jose Garcia Alvarez
  • Patent number: 9394186
    Abstract: The present invention relates to the application of a heterogeneous photocatalysis process for the treatment of industrial wastewater contaminated with recalcitrant compounds and the operating conditions of a pilot plant for implementing said process.
    Type: Grant
    Filed: February 17, 2010
    Date of Patent: July 19, 2016
    Assignee: UNIVERSIDAD DEL VALLE
    Inventors: Fiderman Machuca Martinez, Jose Angel Colina Marquez
  • Patent number: 9017514
    Abstract: Method for production of cellulose and hemicellulose fibers from lignocellulose biomass obtained from sugarcane leaves and buds by applying a process comprising the stages of: a) Diminishing the particle size of the lignocellulose biomass to a range between 3 and 15 mm, b) Subjecting the product obtained to treatment with one or more solvents and/or a mixture of specific catalysts, c) Carry out sudden decompression to an atmospheric pressure, d) Collecting the pretreated material in a cyclone, e) Optionally separating the liquid and solid fractions through washing and filterung f) Optionally, treating the solid fraction in a reactor with a mixture of ethanol and chlorine dioxide, d) Wash the product obtained to achieve cellulose efficiency above 50% and of lignin of 5 to 7%, fiber lengtht in a range to 1,5 to 2,7 mm, breaking length (km) of 7,0 -8,9, Burst index (kPam2/g) of 4,5-7,2 and Tear index (mNm2/g) of 8,2-8, The obtained high-resistance cellulose and hemicellulose is especially suitable for the paper
    Type: Grant
    Filed: July 4, 2012
    Date of Patent: April 28, 2015
    Assignee: Universidad del Valle
    Inventor: Jorge Humberto Borrero
  • Patent number: 8980089
    Abstract: The present application relates to a high-rate anaerobic pool bioreactor (“BLAAT”) as an improved processing unit for treating biodegradable wastewater, which allows the conversion of a low-performance rate traditional system, such as the anaerobic pool, into an efficient, compact system that enables clean energy to be recovered in the from of biogas. The application also describes a process for the anaerobic treatment of wastewater that uses said bioreactor, which optimizes the processes of mixing and contact between the biomass and the substrate and presents a novel process for separating out the biomass by means of improved sedimentation in horizontal laminar flow.
    Type: Grant
    Filed: December 1, 2009
    Date of Patent: March 17, 2015
    Assignee: Universidad del Valle
    Inventor: Miguel Ricardo Pena Varon
  • Publication number: 20140166220
    Abstract: Method for production of cellulose and hemicellulose fibers from lignocellulose biomass obtained from sugarcane leaves and buds by applying a process comprising the stages of: a) Diminishing the particle size of the lignocellulose biomass to a range between 3 and 15 mm, b) Subjecting the product obtained to treatment with one or more solvents and/or a mixture of specific catalysts, c) Carry out sudden decompression to an atmospheric pressure, d) Collecting the pretreated material in a cyclone, e) Optionally separating the liquid and solid fractions through washing and filterung f) Optionally, treating the solid fraction in a reactor with a mixture of ethanol and chlorine dioxide, d) Wash the product obtained to achieve cellulose efficiency above 50% and of lignin of 5 to 7%, fiber lengtht in a range to 1.5 to 2.7 mm, breaking length (km) of 7.0 -8.9, Burst index (kPam2/g) of 4.5-7.2 and Tear index (mNm2/g) of 8.
    Type: Application
    Filed: July 4, 2012
    Publication date: June 19, 2014
    Applicant: UNIVERSIDAD DEL VALLE
    Inventor: Jorge Humberto Borrero
  • Publication number: 20140114310
    Abstract: The current request reports an external fixation device to stabilize bone fractures with adaptable configuration during different stages of surgery or during treatment, through the generation of six degrees of freedom among the bone fragments. The device comprises numerous press-connector means, numerous cylindrical bars, numerous osteosynthesis screws and optionally from one to several rigid rings and one or more extension elements that permit generating diverse stable configurations to treat bone fractures.
    Type: Application
    Filed: October 9, 2010
    Publication date: April 24, 2014
    Applicant: UNIVERSIDAD DEL VALLE
    Inventors: Arlex Leyton Virgen, Andres Machado Caicedo, Jaime Jose Garcia Alvarez
  • Patent number: 8541640
    Abstract: Process for the destruction of toxic residues via oxidation in the presence of water and oxygen developed in homogenous phase at temperatures over 374° C. and pressure of at least 220 atmospheres and a continuous mobile unit easily transferred to treat effluents or contaminated media. This mobile unit is composed of a reactor, which includes pressurization, reaction, cooling, depressurization and sampling zones for the destruction of toxic residues like polychloride biphenyls (PCBs), pyridines, and other hazardous compounds.
    Type: Grant
    Filed: December 17, 2009
    Date of Patent: September 24, 2013
    Assignee: Universidad del Valle
    Inventors: Gustavo Eduardo Bolanos Barrera, Victor Fernando Marulanda Cardona
  • Publication number: 20130224279
    Abstract: The current invention is related to a novel process for the production of aqueous suspensions of micro and nanoparticles of calcium salts smaller than 10 ?m particle size, along with a method to enrich nutritional, nutraceutical, and pharmaceutical beverages with calcium salts. In the process, an aqueous suspension of calcium salt is subjected to pressurization with critical, subcritical, or supercritical carbon dioxide to increase the solubility of the calcium salt, which has a particle size greater than 30 ?m. The resulting solution is expanded through a nozzle to generate a calcium salt suspension of micro and nanoparticles that is imperceptible to sight and taste.
    Type: Application
    Filed: December 8, 2010
    Publication date: August 29, 2013
    Applicant: UNIVERSIDAD DEL VALLE
    Inventors: Gustavo Eduardo Bolanos Barrera, Isabel Maria Mejia Villareal
  • Patent number: 8425755
    Abstract: The invention relates to a novel process for reducing the chemical oxygen demand (COD), total organic carbon (TOC) and total solids of non-contaminating residues from ethanol distilleries, by means of electro-flotation/oxidation techniques using an electrolytic cell outfitted with galvanized steel electrodes as a function of the initial pH of the medium, the current density and the concentration of H2O2.
    Type: Grant
    Filed: December 18, 2009
    Date of Patent: April 23, 2013
    Assignee: Universidad Del Valle
    Inventors: Fiderman Machuca Martinez, Nilson de Jesus Marriaga Cabrales, Javier Andres Davila Rincon
  • Publication number: 20120223024
    Abstract: The present invention relates to the application of a heterogeneous photocatalysis process for the treatment of industrial wastewater contaminated with recalcitrant compounds and the operating conditions of a pilot plant for implementing said process.
    Type: Application
    Filed: February 17, 2010
    Publication date: September 6, 2012
    Applicant: UNIVERSIDAD DEL VALLE
    Inventors: Fiderman Machuca Martinez, Jose Angel Colina Marquez
  • Publication number: 20110299563
    Abstract: The application relates to a device based on the electrothermal method for determining thermal conductivity, which allows the examiniation of various phenomena, with a high level of reliability, through the study of the thermal behaviour of materials. The device is constitated by a sample-carrying cylinder surrounded by a resistance element that creates a radial heat flow in the sample, a cooling system based on a spiral-form heat exchanger incorporated into the thermal device, means for the storage of a fluid and a data-storage device. Furthermore, the present application describes the use of the device in processes for determining the productive potential of the soil (“PPS”) and the examination of the nutritional quality of agro-ecological produce and foods.
    Type: Application
    Filed: December 1, 2009
    Publication date: December 8, 2011
    Applicant: UNIVERSIDAD DEL VALLE
    Inventor: Orlando Zuñiga Escobar
  • Publication number: 20110272347
    Abstract: The present application related to a high-rate anaerobic pool bioreactor (“BLAAT”) as an improved processing unit for treating biodegradable wastewater, which allows the conversion of a low-performance rate traditional system, such as the anaerobic pool, into an efficient, compact system that enables clean energy to be recovered in the from of biogas. The application also describes a process for the anaerobic treatment of wastewater that uses said bioreactor, which optimizes the processes of mixing and contact between the biomass and the substrate and presents a novel process for separating out the biomass by means of improved sedimentation in horizontal laminar flow.
    Type: Application
    Filed: December 1, 2009
    Publication date: November 10, 2011
    Applicant: UNIVERSIDAD DEL VALLE
    Inventor: Miguel Ricardo Pena Varon
  • Publication number: 20110237857
    Abstract: Process for the destruction of toxic residues via oxidation in the presence of water and oxygen developed in homogenous phase at temperatures over 374° C. and pressure of at least 220 atmospheres and a continuous mobile unit easily transferred to treat effluents or contaminated media. This mobile unit is composed of a reactor, which includes pressurization, reaction, cooling, depressurization and sampling zones for the destruction of toxic residues like polychloride biphenyls (PCBs), pyridines, and other hazardous compounds.
    Type: Application
    Filed: December 17, 2009
    Publication date: September 29, 2011
    Applicant: UNIVERSIDAD DEL VALLE
    Inventors: Gustavo Eduardo Bolanos Barrera, Victor Fernando Marulanda Cardona