Patents Assigned to Universidad Nacional de Colombia
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Patent number: 11661440Abstract: The invention provides a series of peptides with N-methyl-D-aspartate (NMDA) receptor modulating activity. Specifically it contains two synthetic peptides acting as ion inflow antagonists through the NMDA receptor with specificity GluN2B and GluN2A NMDA receptor subunits and a peptide having agonist activity regarding the NMDA receptor in rat hippocampal neuron cultures.Type: GrantFiled: January 11, 2021Date of Patent: May 30, 2023Assignee: Universidad Nacional de ColombiaInventors: Edgar Antonio Reyes Montaño, Edwin Alfredo Reyes Guzmán, Nohora Angélica Vega Castro
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Patent number: 11415506Abstract: The invention provides an in vitro method for the determination of sun protection factor (SPF), in order to gain reproducibility and accuracy and replace the use of tests on living beings. Natural substrates of the human skin, like hyaluronic acid are tested in the form of solutions or in the form of a solid film in a modified spectrophotometer, at concentrations below 1% w/v. Once calibrated, the method is used to corroborate the protection factor offered by commercial sunscreens.Type: GrantFiled: July 25, 2018Date of Patent: August 16, 2022Assignee: UNIVERSIDAD NACIONAL DE COLOMBIAInventors: Bibiana Margarita Rosa Vallejo Díaz, Clara Eugenia Plazas Bonilla, Helber De Jesús Barbosa Barbosa, Nestor Jaime Torres Salcedo, Angie Viviana Vitola Domínguez, Aura Rocío Hernández Camargo
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Patent number: 10689418Abstract: The invention provides a series of peptides with N-methyl-D-aspartate (NMDA) receptor modulating activity. Specifically it contains two synthetic peptides acting as ion inflow antagonists through the NMDA receptor with specificity GluN2B and GluN2A NMDA receptor subunits and a peptide having agonist activity regarding the NMDA receptor in rat hippocampal neuron cultures.Type: GrantFiled: December 22, 2016Date of Patent: June 23, 2020Assignee: Universidad Nacional de ColombiaInventors: Edgar Antonio Reyes Montaño, Edwin Alfredo Reyes Guzmán, Nohora Angélica Vega Castro
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Patent number: 10450232Abstract: The present invention corresponds to a cement formulation based on sulfoaluminate comprising a specific Ye'elimite crystal proportion having enhanced mechanical resistance, setting and low CO2 emission features. A concrete obtained when mixing said formulation with water and gypsum is further described, having a superior performance at initial ages compared to concrete obtained from Portland cement.Type: GrantFiled: December 3, 2015Date of Patent: October 22, 2019Assignees: Universidad Nacional de Colombia, Cementos Argos S.A.Inventors: Jorge Iván Tobón, Carolina Giraldo Torres, Ariel Berrio Solarte, Diana Londoño Zuluaga
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Patent number: 10031184Abstract: The present invention discloses a method for the detection and diagnosis of faults in running electric machines.Type: GrantFiled: March 4, 2014Date of Patent: July 24, 2018Assignees: Universidad Nacional de Colombia, Empresas Publicas de Medellin E.S.P.Inventors: Raúl Esteban Jimenez Mejia, Guillermo León Mesa Betancur
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Patent number: 9915919Abstract: A microscope, method and computer program for obtaining quantitative phase images by digital holographic microscopy. The microscope includes: a coherent light source (1) and a beam splitter (3) for generating an object beam (Lo) for illuminating a sample, and a reference beam (Lr); an optical system with a main optical path making up a telecentric afocal system, and a reference optical path; and recording means (12) recording a hologram of said sample in the image plane of the optical system. The method includes recording a hologram in the image plane of an optical telecentric afocal system. The computer program is adapted for implementing part of the steps of the method.Type: GrantFiled: October 27, 2014Date of Patent: March 13, 2018Assignees: UNIVERSITAT DE VALENCIA, UNIVERSIDAD NACIONAL DE COLOMBIAInventors: Emilio Sánchez Ortiga, Manuel Martínez Corral, Ana Doblas Expósito, Genaro Saavedra Tortosa, Jorge Iván García Sucerquia
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Patent number: 9765283Abstract: This invention discloses a reaction system for producing fatty-acid alkyl esters using liquid film reactors, with countercurrent flow scheme based on the alcoholysis of fats and oils. Reaction system comprises a descending film reactor using semi-structured packing for generating interfacial area. It is fed through the bottom with oil or fat, and with a mixture containing alcohol, glycerol and catalyst through an intermediate stage. Products are a mixture of fatty-acid alkyl esters, alcohol and catalyst and alcohol, glycerol and catalyst, exit via the top and the bottom of the reactor, respectively. Volumetric packing fraction is between 2% and 50%, reaction temperature from 25 to 180° C., molar ratio alcohol to oil between 3:1 and 10:1, and CH3OH, NaOH, KOH, or their mixtures (0.5% to 3% based on the oil mass flow rate). Conversion and yield in a single reaction step are greater than 99.7% and 99.9%, respectively.Type: GrantFiled: January 28, 2014Date of Patent: September 19, 2017Assignee: UNIVERSIDAD NACIONAL DE COLOMBIAInventors: Paulo Cesar Narvaez Rincon, Juan Guillermo Cadavid Estrada, Ruben Darío Godoy Silva, Gerardo Rodriguez Niño
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Publication number: 20160302888Abstract: The invention relates to an orthodontic tool for the placement, positioning and attaching of brackets using a direct or indirect method, said tool comprising two parts: a body for manipulating the device (1) and a point (2). The shape of the body (1) is compatible with the hand and offers the user control and comfort when arranging the bracket (100) on the target—the target being the mesiodistal centre of the dental piece or tooth—at a predetermined height (202), resulting in precision and accuracy.Type: ApplicationFiled: August 15, 2014Publication date: October 20, 2016Applicant: UNIVERSIDAD NACIONAL DE COLOMBIAInventors: Gabriel GARCÍA ACOSTA, Karen LANGE MORALES, David Ernesto PUENTES LAGOS, Sara Estela PARADA PARADA, Manuel Ricardo RUIZ ORTIZ, Ana María GARZÓN PACHECO, William Ricardo LEÓN CASTELLANOS, Juan Ricardo ÁLVAREZ, Carlos Julio VANEGAS MATA, Jhon Walther NUÑEZ VILORIA
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Publication number: 20160252880Abstract: A microscope, method and computer program for obtaining quantitative phase images by digital holographic microscopy. The microscope includes: a coherent light source (1) and a beam splitter (3) for generating an object beam (Lo) for illuminating a sample, and a reference beam (Lr); an optical system with a main optical path making up a telecentric afocal system, and a reference optical path; and recording means (12) recording a hologram of said sample in the image plane of the optical system. The method includes recording a hologram in the image plane of an optical telecentric afocal system. The computer program is adapted for implementing part of the steps of the method.Type: ApplicationFiled: October 30, 2013Publication date: September 1, 2016Applicants: UNIVERSITAT DE VALENCIA, UNIVERSIDAD NACIONAL DE COLOMBIAInventors: Emilio SÁNCHEZ ORTIGA, Manuel MARTÍNEZ CORRAL, Ana DOBLAS EXPÓSITO, Genaro SAAVEDRA TORTOSA, Jorge Iván GARCÍA SUCERQIUA
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Publication number: 20150368587Abstract: The present invention discloses a reaction system for producing fatty-acid alkyl esters using packed reactors, particularly liquid-film reactors, with a countercurrent feed current flow scheme based on the alcoholysis of oils and fats, specifically the methanolysis of palm oil and soya oil. The reaction system comprises a descending liquid-film reactor that uses as semi-structured packing for generating an interface area. The reactor is fed, separately, with the oil or fat, through the bottom of the reactor, and a mixture containing alcohol, glycerol and catalyst, which may be fed in in an intermediate stage. It is also possible, optionally, to feed in a second stream of the mixture of alcohol, glycerol and catalyst in proportions different from those of the first stream, either in an intermediate stage of the reactor or through the top thereof.Type: ApplicationFiled: January 28, 2014Publication date: December 24, 2015Applicant: UNIVERSIDAD NACIONAL DE COLOMBIAInventors: Paulo Cesar NARVAEZ RINCON, Juan Guillermo CADAVID ESTRADA, Ruben Darío GODOY SILVA, Gerardo RODRIGUEZ NIÑO
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Patent number: 8642296Abstract: A microorganism identified as a Lactococcus lactis strain (NRRL B-30656) produces an extracellular transferase enzyme when cultured and grown in sucrose-containing medium, which can be purified when it is brought into contact with a sucrose-based medium in suitable temperature and pH conditions, thereby producing a glucose and fructose polymer.Type: GrantFiled: December 21, 2004Date of Patent: February 4, 2014Assignee: Universidad Nacional de ColombiaInventors: Sonia Amparo Ospina Sánchez, Dolly Montoya Castaño, Gustavo Buitrago Hurtado, Jairo Alonso Ceron Salamanca, Oscar Caicedo Zamora
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Patent number: 7041647Abstract: This invention provides a novel synthetic peptide (P1) of 26 amino acids, which inhibits the microbial growing. Peptide P1 also shows ionophoric activity in rat liver mitochondria. Furthermore, this invention provides pharmaceutical compositions and compositions for agricultural use, which contain the peptide of the invention.Type: GrantFiled: January 7, 2004Date of Patent: May 9, 2006Assignees: Corporacion Para Investigaciones Biologicas, Universidad de Antiqquia, Fundacion Instituto de Inmunologia de Columbia, Universidad Nacional de ColombiaInventors: Viktor Lemeshko, Fanny Guzman, Manuel E. Patarroyo, Cesar Segura, Sergio Orduz
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Patent number: 6159887Abstract: A catalytic composition useful in the catalytic-cracking of hydrocarbons is described, which contains at least one agent causing the inactivation of vanadium, which may be present in the hydrocarbons as a contaminant. These agents obtain inactivation of vanadium without substantial loss of catalytic activity and selectivity.Type: GrantFiled: August 28, 1998Date of Patent: December 12, 2000Assignees: Empresa Colombiana de Petroleos Ecopetrol, Universidad Nacional de ColombiaInventors: Carlos Alexander Trujillo, Uriel Navarro Uribe, Luis Alfredo Oviedo Aguiar