Patents Assigned to Universidad Nacional de Colombia
  • Patent number: 11661440
    Abstract: The invention provides a series of peptides with N-methyl-D-aspartate (NMDA) receptor modulating activity. Specifically it contains two synthetic peptides acting as ion inflow antagonists through the NMDA receptor with specificity GluN2B and GluN2A NMDA receptor subunits and a peptide having agonist activity regarding the NMDA receptor in rat hippocampal neuron cultures.
    Type: Grant
    Filed: January 11, 2021
    Date of Patent: May 30, 2023
    Assignee: Universidad Nacional de Colombia
    Inventors: Edgar Antonio Reyes Montaño, Edwin Alfredo Reyes Guzmán, Nohora Angélica Vega Castro
  • Patent number: 11415506
    Abstract: The invention provides an in vitro method for the determination of sun protection factor (SPF), in order to gain reproducibility and accuracy and replace the use of tests on living beings. Natural substrates of the human skin, like hyaluronic acid are tested in the form of solutions or in the form of a solid film in a modified spectrophotometer, at concentrations below 1% w/v. Once calibrated, the method is used to corroborate the protection factor offered by commercial sunscreens.
    Type: Grant
    Filed: July 25, 2018
    Date of Patent: August 16, 2022
    Assignee: UNIVERSIDAD NACIONAL DE COLOMBIA
    Inventors: Bibiana Margarita Rosa Vallejo Díaz, Clara Eugenia Plazas Bonilla, Helber De Jesús Barbosa Barbosa, Nestor Jaime Torres Salcedo, Angie Viviana Vitola Domínguez, Aura Rocío Hernández Camargo
  • Patent number: 10689418
    Abstract: The invention provides a series of peptides with N-methyl-D-aspartate (NMDA) receptor modulating activity. Specifically it contains two synthetic peptides acting as ion inflow antagonists through the NMDA receptor with specificity GluN2B and GluN2A NMDA receptor subunits and a peptide having agonist activity regarding the NMDA receptor in rat hippocampal neuron cultures.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: June 23, 2020
    Assignee: Universidad Nacional de Colombia
    Inventors: Edgar Antonio Reyes Montaño, Edwin Alfredo Reyes Guzmán, Nohora Angélica Vega Castro
  • Patent number: 10450232
    Abstract: The present invention corresponds to a cement formulation based on sulfoaluminate comprising a specific Ye'elimite crystal proportion having enhanced mechanical resistance, setting and low CO2 emission features. A concrete obtained when mixing said formulation with water and gypsum is further described, having a superior performance at initial ages compared to concrete obtained from Portland cement.
    Type: Grant
    Filed: December 3, 2015
    Date of Patent: October 22, 2019
    Assignees: Universidad Nacional de Colombia, Cementos Argos S.A.
    Inventors: Jorge Iván Tobón, Carolina Giraldo Torres, Ariel Berrio Solarte, Diana Londoño Zuluaga
  • Patent number: 10031184
    Abstract: The present invention discloses a method for the detection and diagnosis of faults in running electric machines.
    Type: Grant
    Filed: March 4, 2014
    Date of Patent: July 24, 2018
    Assignees: Universidad Nacional de Colombia, Empresas Publicas de Medellin E.S.P.
    Inventors: Raúl Esteban Jimenez Mejia, Guillermo León Mesa Betancur
  • Patent number: 9915919
    Abstract: A microscope, method and computer program for obtaining quantitative phase images by digital holographic microscopy. The microscope includes: a coherent light source (1) and a beam splitter (3) for generating an object beam (Lo) for illuminating a sample, and a reference beam (Lr); an optical system with a main optical path making up a telecentric afocal system, and a reference optical path; and recording means (12) recording a hologram of said sample in the image plane of the optical system. The method includes recording a hologram in the image plane of an optical telecentric afocal system. The computer program is adapted for implementing part of the steps of the method.
    Type: Grant
    Filed: October 27, 2014
    Date of Patent: March 13, 2018
    Assignees: UNIVERSITAT DE VALENCIA, UNIVERSIDAD NACIONAL DE COLOMBIA
    Inventors: Emilio Sánchez Ortiga, Manuel Martínez Corral, Ana Doblas Expósito, Genaro Saavedra Tortosa, Jorge Iván García Sucerquia
  • Patent number: 9765283
    Abstract: This invention discloses a reaction system for producing fatty-acid alkyl esters using liquid film reactors, with countercurrent flow scheme based on the alcoholysis of fats and oils. Reaction system comprises a descending film reactor using semi-structured packing for generating interfacial area. It is fed through the bottom with oil or fat, and with a mixture containing alcohol, glycerol and catalyst through an intermediate stage. Products are a mixture of fatty-acid alkyl esters, alcohol and catalyst and alcohol, glycerol and catalyst, exit via the top and the bottom of the reactor, respectively. Volumetric packing fraction is between 2% and 50%, reaction temperature from 25 to 180° C., molar ratio alcohol to oil between 3:1 and 10:1, and CH3OH, NaOH, KOH, or their mixtures (0.5% to 3% based on the oil mass flow rate). Conversion and yield in a single reaction step are greater than 99.7% and 99.9%, respectively.
    Type: Grant
    Filed: January 28, 2014
    Date of Patent: September 19, 2017
    Assignee: UNIVERSIDAD NACIONAL DE COLOMBIA
    Inventors: Paulo Cesar Narvaez Rincon, Juan Guillermo Cadavid Estrada, Ruben Darío Godoy Silva, Gerardo Rodriguez Niño
  • Publication number: 20160302888
    Abstract: The invention relates to an orthodontic tool for the placement, positioning and attaching of brackets using a direct or indirect method, said tool comprising two parts: a body for manipulating the device (1) and a point (2). The shape of the body (1) is compatible with the hand and offers the user control and comfort when arranging the bracket (100) on the target—the target being the mesiodistal centre of the dental piece or tooth—at a predetermined height (202), resulting in precision and accuracy.
    Type: Application
    Filed: August 15, 2014
    Publication date: October 20, 2016
    Applicant: UNIVERSIDAD NACIONAL DE COLOMBIA
    Inventors: Gabriel GARCÍA ACOSTA, Karen LANGE MORALES, David Ernesto PUENTES LAGOS, Sara Estela PARADA PARADA, Manuel Ricardo RUIZ ORTIZ, Ana María GARZÓN PACHECO, William Ricardo LEÓN CASTELLANOS, Juan Ricardo ÁLVAREZ, Carlos Julio VANEGAS MATA, Jhon Walther NUÑEZ VILORIA
  • Publication number: 20160252880
    Abstract: A microscope, method and computer program for obtaining quantitative phase images by digital holographic microscopy. The microscope includes: a coherent light source (1) and a beam splitter (3) for generating an object beam (Lo) for illuminating a sample, and a reference beam (Lr); an optical system with a main optical path making up a telecentric afocal system, and a reference optical path; and recording means (12) recording a hologram of said sample in the image plane of the optical system. The method includes recording a hologram in the image plane of an optical telecentric afocal system. The computer program is adapted for implementing part of the steps of the method.
    Type: Application
    Filed: October 30, 2013
    Publication date: September 1, 2016
    Applicants: UNIVERSITAT DE VALENCIA, UNIVERSIDAD NACIONAL DE COLOMBIA
    Inventors: Emilio SÁNCHEZ ORTIGA, Manuel MARTÍNEZ CORRAL, Ana DOBLAS EXPÓSITO, Genaro SAAVEDRA TORTOSA, Jorge Iván GARCÍA SUCERQIUA
  • Publication number: 20150368587
    Abstract: The present invention discloses a reaction system for producing fatty-acid alkyl esters using packed reactors, particularly liquid-film reactors, with a countercurrent feed current flow scheme based on the alcoholysis of oils and fats, specifically the methanolysis of palm oil and soya oil. The reaction system comprises a descending liquid-film reactor that uses as semi-structured packing for generating an interface area. The reactor is fed, separately, with the oil or fat, through the bottom of the reactor, and a mixture containing alcohol, glycerol and catalyst, which may be fed in in an intermediate stage. It is also possible, optionally, to feed in a second stream of the mixture of alcohol, glycerol and catalyst in proportions different from those of the first stream, either in an intermediate stage of the reactor or through the top thereof.
    Type: Application
    Filed: January 28, 2014
    Publication date: December 24, 2015
    Applicant: UNIVERSIDAD NACIONAL DE COLOMBIA
    Inventors: Paulo Cesar NARVAEZ RINCON, Juan Guillermo CADAVID ESTRADA, Ruben Darío GODOY SILVA, Gerardo RODRIGUEZ NIÑO
  • Patent number: 8642296
    Abstract: A microorganism identified as a Lactococcus lactis strain (NRRL B-30656) produces an extracellular transferase enzyme when cultured and grown in sucrose-containing medium, which can be purified when it is brought into contact with a sucrose-based medium in suitable temperature and pH conditions, thereby producing a glucose and fructose polymer.
    Type: Grant
    Filed: December 21, 2004
    Date of Patent: February 4, 2014
    Assignee: Universidad Nacional de Colombia
    Inventors: Sonia Amparo Ospina Sánchez, Dolly Montoya Castaño, Gustavo Buitrago Hurtado, Jairo Alonso Ceron Salamanca, Oscar Caicedo Zamora
  • Patent number: 7041647
    Abstract: This invention provides a novel synthetic peptide (P1) of 26 amino acids, which inhibits the microbial growing. Peptide P1 also shows ionophoric activity in rat liver mitochondria. Furthermore, this invention provides pharmaceutical compositions and compositions for agricultural use, which contain the peptide of the invention.
    Type: Grant
    Filed: January 7, 2004
    Date of Patent: May 9, 2006
    Assignees: Corporacion Para Investigaciones Biologicas, Universidad de Antiqquia, Fundacion Instituto de Inmunologia de Columbia, Universidad Nacional de Colombia
    Inventors: Viktor Lemeshko, Fanny Guzman, Manuel E. Patarroyo, Cesar Segura, Sergio Orduz
  • Patent number: 6159887
    Abstract: A catalytic composition useful in the catalytic-cracking of hydrocarbons is described, which contains at least one agent causing the inactivation of vanadium, which may be present in the hydrocarbons as a contaminant. These agents obtain inactivation of vanadium without substantial loss of catalytic activity and selectivity.
    Type: Grant
    Filed: August 28, 1998
    Date of Patent: December 12, 2000
    Assignees: Empresa Colombiana de Petroleos Ecopetrol, Universidad Nacional de Colombia
    Inventors: Carlos Alexander Trujillo, Uriel Navarro Uribe, Luis Alfredo Oviedo Aguiar