Patents Assigned to Universidad Nacional de Tucumán
  • Chemically coupled transporter for low-hydrophobicity bioactive drugs into the central nervous system
    Patent number: 11951170
    Abstract: The present disclosure provides a compound comprising a modified tetracycline derivative, covalently coupled through a linker to a low-hydrophobicity bioactive molecule useful for treating neurodegenerative diseases, wherein the modified tetracycline derivative is optionally defined by the following formula:
    Type: Grant
    Filed: March 14, 2023
    Date of Patent: April 9, 2024
    Assignees: Skybio LLC, Consejo Nacional de Investigaciones Cientificas y Ténicas (Conicet), Universidad Nacional de Tucumán, Universidad de Buenos Aires, Sistema Provincial De Salud De Tucumán
    Inventors: Oscar José Varela, Rosana Nieves Chehín, Cesar Luis Ávila, Sergio Benjamin Socías, Diego Ploper, Esteban Vera Pingitore, Analía Silvina Chaves, Martin Luong, Verónica Elena Manzano, Rodrigo Hernán Tomas Grau, Maria Florencia González Lizárraga, Adriana Andrea Kolender, Agustín Osvaldo Pernicone
  • Pharmaceutical composition for topical wound treatment
    Patent number: 11382913
    Abstract: A pharmaceutical composition for topical wound treatment comprising one or more nitrogenous heterocyclic compound of 5 or 6 atoms with imide group; one or more deoxyribonuclease enzyme with activity pH between 4.5 and 6.5; and one or more carboxylic acid; kits and process to obtain this pharmaceutical composition and uses for wounds treatment.
    Type: Grant
    Filed: May 18, 2021
    Date of Patent: July 12, 2022
    Assignees: CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS, UNIVERSIDAD NACIONAL DE TUCUMAN, UNITECH INC.
    Inventors: Alberto Ramos Vernieri, Maria De Los Angeles Lazarte, Romina Mabel Chavez Jara, Nicolas Abel Cerusico
  • Method for inducing resistance to stress caused by pathogens in plants
    Patent number: 9534025
    Abstract: Polypeptide having activity inducing pathogen plant defence, nucleotide sequence encodes it, microorganism, compositions and methods. The polypeptide is a subtilisin derived from a strain of Acremonium strictum. The polypeptide is encoded by the nucleotide sequence SEQ ID NO: 1 or sequences at least 90% homologous to the same and has the amino acid sequence SEQ ID NO: 2 or sequences at least 90% homologous to the same.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: January 3, 2017
    Assignees: UNIVERSIDAD NACIONAL DE TUCUMAN, CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET)
    Inventors: Atilio Pedro Castagnaro, Juan Carlos Diaz Ricci, Nadia Regina Chalfoun, Josefina Racedo, Sergio Miguel Salazar
  • Polypeptide having inducing activity for the defence against biotic stress in plants, nucleotide sequence encoding the same, microorganism, compositions and methods
    Patent number: 9357786
    Abstract: Polypeptide having activity inducing pathogen plant defense, nucleotide sequence encodes it, microorganism, compositions and methods. The polypeptide is a subtilisin derived from a strain of Acremonium strictum. The polypeptide is encoded by the nucleotide sequence SEQ ID NO: 1 or sequences at least 90% homologous to the same and has the amino acid sequence SEQ ID NO: 2 or sequences at least 90% homologous to the same.
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: June 7, 2016
    Assignees: UNIVERSIDAD NACIONAL DE TUCUMAN, CONSEJO NACIONAL DE INVESTIGACIONES CIENTIFICAS Y TECNICAS (CONICET)
    Inventors: Atilio Pedro Castagnaro, Juan Carlos Diaz Ricci, Nadia Regina Chalfoun, Josefina Racedo, Sergio Miguel Salazar