Abstract: The invention relates to a method for the diagnosis of liver fibrosis, comprising detecting the level of expression of the gene GATA-4, or the quantity of the protein GATA-4, in the isolated biological sample of liver tissue. The invention also relates to a diagnosis kit.
Type:
Application
Filed:
April 30, 2014
Publication date:
June 27, 2019
Applicants:
UNIVERSIDAD PABLO DE OLAVIDE, UNIVERSIDAD DE SEVILLA, SERVICIO ANDALUZ DE SALUD, FUNDACIÓN PÚBLICA ANDALUZA PARA LA GESTIÓN DE LA INVESTIGACIÓN EN SALUD DE SEVILLA
Inventors:
Ana Isabel Rojas Gonzalez, David Cano Gonzalez, Irene Delgado Sainz, Bernat Soria Escoms, Francisco Martin Bermudez, Manuel Romero Gomez
Abstract: The present invention relates to the use of the inhibitor of the activity of the steroid sulfatase enzyme STX64 for the treatment of ageing and, therefore, to increase the longevity of individuals or improve their quality of life. It also relates to a cosmetic composition that comprises said inhibitor for that purpose.
Type:
Application
Filed:
March 26, 2014
Publication date:
December 15, 2016
Applicant:
Universidad Pablo de Olavide
Inventors:
Manuel Jesus Munoz Ruiz, Maria Mercedes Perez Jimenez
Abstract: The present invention relates to a method of obtaining metal nanoparticles functionalized with fluorescent organic molecules by means of the treatment of one or more metal salts with a reducing agent in the presence of a fluorescent organic molecule. The invention also relates to the metal nanoparticles obtainable by said method and to their use for detecting molecules and analytes.
Type:
Application
Filed:
March 23, 2012
Publication date:
August 21, 2014
Applicants:
UNIVERSIDAD PABLO DE OLAVIDE, CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS C.S.I.C.
Inventors:
Ana Paula Zaderenko Partida, Carlos Caro Salazar, José Mejías Romero, Maria Jesús Sayagués De Vega
Abstract: The invention relates to the use of morin and mangiferin, the pharmaceutically acceptable salts, prodrugs and/or solvates thereof in the production of a pharmaceutical composition for the prevention and/or treatment of a neurodegenerative disease and symptoms associated with ageing, as well as to food compositions comprising said compounds.
Type:
Grant
Filed:
December 29, 2006
Date of Patent:
July 9, 2013
Assignees:
Universidad del Pais Vasco, Universidad Pablo de Olavide
Inventors:
Carlos Matute Almau, Maria Victoria Sanchez Gomez, Rosario Campos Esparza, Elena Alberdi Alfonso, Miroslav Gottlieb, Gaskon Ibarretxe Bilbao, Jose Maria Delgado Garcia, Agnes Gruart I Masso, Rocio Leal Campanario
Abstract: The invention relates to the use of morin and mangiferin, the pharmaceutically acceptable salts, prodrugs and/or solvates thereof in the production of a pharmaceutical composition for the prevention and/or treatment of a neurodegenerative disease and symptoms associated with ageing, as well as to food compositions comprising said compounds.
Type:
Application
Filed:
December 29, 2006
Publication date:
May 21, 2009
Applicants:
UNIVERSIDAD DEL PAIS VASCO, UNIVERSIDAD PABLO DE OLAVIDE
Inventors:
Carlos Matute Almau, Maria Victoria Sanchez Gomez, Rosario Campos Esparza, Elena Alberdi Alfonso, Miroslav Gottlieb, Gaskon Ibarretxe Bilbao, Jose Maria Delgado Garcia, Agnes Gruart I Masso, Rocio Leal Campanario