Abstract: A purified novel enzyme protein, UGPPase, which naturally occurs in animal cells, its productions of recombinant technology, an antibody to the enzyme protein, a method of carrying out ELISA for measurement of the amount of UGPPase in an analyte and a method for determination of UDPG in a sample. The one-way enzyme protein catalyses hydrolysis of UDP-glucose, the precursor molecule of glycogen, into glucose-1-phosphate (G1P) and uridine 5?-monophosphate (UMP).
Type:
Grant
Filed:
March 17, 2003
Date of Patent:
March 4, 2008
Assignees:
JCR Pharmaceuticals Co., Ltd., Universidad Publica De Navarra Campus Arrosadia
Inventors:
Javier Pozueta Romero, Edurne Baroja Fernandez, Francisco Jose Munoz, Imbak Shu, Ryuji Yamamoto