Patents Assigned to UNIVERSIDADE DO ALGARVE
  • METHODS OF ANALYSIS OF 17Q22 POLYMORPHISMS ASSOCIATED WITH CANCER AND USES THEREOF
    Publication number: 20240336979
    Abstract: The invention relates to a method of predicting a subject's likelihood of being diagnosed with a malignant cancer, comprising measuring the relative expression level of a reference allele and an alternative allele of selected cancer risk associated polymorphisms in 17q22 in blood samples.
    Type: Application
    Filed: June 6, 2024
    Publication date: October 10, 2024
    Applicant: UNIVERSIDADE DO ALGARVE
    Inventors: Joana GONÇALVES DE GOUVEIA MAIA XAVIER, Ana Teresa LUÍS LOPES MAIA, Filipa Alexandra OLEIRO ESTEVES RIBEIROS
  • METHODS OF ANALYSIS OF ALLELIC EXPRESSION OF PIK3CA IN CANCER AND USES THEREOF
    Publication number: 20240068046
    Abstract: The invention provides a method of identifying a subset of cancer patients with a poor prognosis, comprising comparing the allelic expression of a mutant and wildtype PIK3CA allele in a patient sample. The invention further teaches the use of drugs targeting the mutant PI3K protein in a subset of patients which are determined to express the a mutant PIK3CA allele above a certain threshold, in addition to a kit, or system with which PIK3CA allelic expression may be assessed.
    Type: Application
    Filed: September 3, 2023
    Publication date: February 29, 2024
    Applicant: UNIVERSIDADE DO ALGARVE
    Inventors: Ana Teresa LUÍS LOPES MAIA, Joana GONÇALVES DE GOUVEIA MAIA XAVIER, Lizelle WINKELSTRÖTER CORREIA, Ramiro Emanuel MAGNO MORGADO