Abstract: The present invention relates to humanized antibodies that specifically bind to human BTN3A and their use in treating cancer and infectious disorders.

Abstract: A luminescent hybrid nanomaterial comprising: at least one inorganic nanomaterial comprising an inorganic first compound; and at least one second compound comprising a first aggregation-induced emission moiety, wherein the at least one second compound is grafted on at least part of a surface of the inorganic first compound.

Abstract: The invention relates to a device (II) for three-dimensional focusing in a microscope (I) with a given resolution, comprising: —a detector (119) making it possible to determine, in a given measuring plane, a phase and intensity image of an electromagnetic field resulting from the interaction of an incident light wave with a reference object (105) situated in a reference medium with a given index and having a complex refractive index, the real part and/or the imaginary part of which differs from the real part and/or the imaginary part, respectively, of the refractive index of the reference medium; —computation means (121) making it possible to determine a three-dimensional position variation of the reference object (105) from at least one phase and intensity image.

Abstract: A composition for treating Fragile X syndrome in a subject in need thereof, wherein the composition includes an effective amount of a modulator of a chloride transporter.

Abstract: The use of spider venom, molecules or synthetic analogs thereof for skin whitening. Also, compositions that include spider venom, molecules or synthetic analogs thereof for skin whitening/depigmenting, and a non-therapeutic method for whitening human skin that includes topically applying an effective amount on human skin of the composition.

Abstract: A luminescent hybrid nanomaterial comprising: at least one inorganic nanomaterial comprising an inorganic first compound; and at least one second compound comprising a first aggregation-induced emission moiety, wherein the at least one second compound is grafted on at least part of a surface of the inorganic first compound.

Abstract: According to one aspect, the invention relates to a device for detecting a resonant non-linear optical signal of Stimulated Raman Scattering (SRS) type induced in a sample. The device comprises electro-optical means for making interact in the sample, at a first modulation frequency, trains of light pulses of angular frequencies ?1 and ?2 and, at a second modulation frequency, trains of light pulses of angular frequencies ?2 and ?3, such that ?2??1=?3??2=?R where ?R is a molecular vibrational resonant angular frequency of the sample. Moreover, the device comprises means for synchronous detection at the first and second modulation frequencies of non-linear optical signals resulting from the interaction of the light pulses in the sample, and electronic processing means making it possible to obtain, from electronic signals resulting from the synchronous detection, a signal characterizing the molecular vibrational resonance of the sample.

Abstract: According to one aspect, the invention relates to a device for detecting a resonant non-linear optical signal of Stimulated Raman Scattering (SRS) type induced in a sample. The device comprises electro-optical means for making interact in the sample, at a first modulation frequency, trains of light pulses of angular frequencies ?1 and ?2 and, at a second modulation frequency, trains of light pulses of angular frequencies ?2 and ?3, such that ?2??1=?3??2=?R where ?R is a molecular vibrational resonant angular frequency of the sample. Moreover, the device comprises means for synchronous detection at the first and second modulation frequencies of non-linear optical signals resulting from the interaction of the light pulses in the sample, and electronic processing means making it possible to obtain, from electronic signals resulting from the synchronous detection, a signal characterizing the molecular vibrational resonance of the sample.

Abstract: The use of spider venom, molecules or synthetic analogs thereof for skin whitening. Also, compositions that include spider venom, molecules or synthetic analogs thereof for skin whitening/depigmenting, and a non-therapeutic method for whitening human skin that includes topically applying an effective amount on human skin of the composition.

Abstract: A method of generating electrical energy in an integrated circuit that may include setting into motion a (3D) three-dimensional enclosed space in the integrated circuit. The 3D enclosed space may include a piezoelectric element and a free moving object therein. The method may also include producing the electrical energy from impact between the free moving object and the piezoelectric element during the motion.

Abstract: A method of generating electrical energy in an integrated circuit that may include setting into motion a (3D) three-dimensional enclosed space in the integrated circuit. The 3D enclosed space may include a piezoelectric element and a free moving object therein. The method may also include producing the electrical energy from impact between the free moving object and the piezoelectric element during the motion.

Abstract: A method of generating electrical energy in an integrated circuit that may include setting into motion a (3D) three-dimensional enclosed space in the integrated circuit. The 3D enclosed space may include a piezoelectric element and a free moving object therein. The method may also include producing the electrical energy from impact between the free moving object and the piezoelectric element during the motion.

Abstract: A method of generating electrical energy in an integrated circuit that may include setting into motion a (3D) three-dimensional enclosed space in the integrated circuit. The 3D enclosed space may include a piezoelectric element and a free moving object therein. The method may also include producing the electrical energy from impact between the free moving object and the piezoelectric element during the motion.