Patents Assigned to UNIVERSITÉ D'AVIGNON
  • Patent number: 11124584
    Abstract: The invention pertains to an improved PVDC composition including certain dienophiles qualified for food contact, which possess an optimized balance of effectiveness in preventing discoloration upon exposure to radiation, with no negative impact on the barrier properties, in particular sorbate esters of formula (I), wherein R1 is a C1-C12 hydrocarbon group, preferably a C1-C6 alkyl group, to layers made therefrom, to multi-layer assemblies comprising the same, and to the use of said assemblies for packaging, in particular for packaging foodstuffs.
    Type: Grant
    Filed: November 25, 2016
    Date of Patent: September 21, 2021
    Assignees: Solvay SA, Centre National de la Recherche Scientifique, Université d'Aix-Marseille
    Inventors: Elodie Chauvet, Didier Gigmes, Yohann Guillaneuf, Agnès Chapotot, Jérôme Vinas, Pascal Dewael, Yves Vanderveken
  • Publication number: 20210285967
    Abstract: The invention relates to an in vitro or ex vivo method for differentially diagnosing a bipolar disorder and a major depressive disorder in a human patient in a need thereof presenting depressive symptoms, comprising the following steps: providing a biological sample from said patient; determining, from said biological sample, the abundance of at least one of the following cytokines TNF-?, IFN-?, IL-6, IL-10, IL-12p40, IL-15, IL-16, IL-17A and IL-27; and diagnosing a bipolar disorder or a major depressive disorder from the determination of the abundance of the at least one of the following cytokines TNF-?, IFN-?, IL-6, IL-10, IL-12p40, IL-15, IL-16, IL-17A and IL-27.
    Type: Application
    Filed: October 4, 2019
    Publication date: September 16, 2021
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE, UNIVERSITÉ D'AIX-MARSEILLE (AMU), UNIVERSITÉ CÔTE D'AZUR, ASSISTANCE PUBLIQUE - HÔPITAUX DE MARSEILLE (AP-HM), SORBONNE UNIVERSITE, UNIVERSITE DE MONTPELLIER, CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER
    Inventors: Wafa Bel Haj Ali, El Chérif Ibrahim, Raoul Belzeaux, Lionel Fillatre, Nicolas Glaichenhaus, Philippe Courtet, Emanuela Martinuzzi, Susana Do Carmo Pinto Barbosa
  • Patent number: 11120999
    Abstract: A plasma etching method includes a physisorption step for causing an adsorbate that is based on first processing gas to be physisorbed onto a film to be etched, while cooling an object to be processed on which the film to be etched is provided; and an etching step for etching the film to be etched by causing the adsorbate to react with the film to be etched, using the plasma of second processing gas.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: September 14, 2021
    Assignees: TOKYO ELECTRON LIMITED, UNIVERSITE D'ORLEANS
    Inventors: Koichi Yatsuda, Kaoru Maekawa, Nagisa Sato, Kumiko Ono, Shigeru Tahara, Jacques Faguet, Remi Dussart, Thomas Tillocher, Philippe Lefaucheux, Gaëlle Antoun
  • Patent number: 11118200
    Abstract: The present invention relates to the preparation of amines from aldehydes and ketones by reductive amination with enzymes having a reductive aminase activity on aldehydes and ketones devoid of any carboxyl group gamma of the carbonyl group. The invention also relates to the enzymes per se and their uses in biocatalysis. The enzymes are derived from Mycobacterium smegmatis and vaccae, Cystobacter fuscus, Microbacterium sp. and Aminomonas paucivorans.
    Type: Grant
    Filed: July 5, 2018
    Date of Patent: September 14, 2021
    Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITE D'EVRY VAL D'ESSONNE (UEVE)
    Inventors: Carine Vergne-Vaxelaire, Véronique De Berardinis, Anne Zaparucha
  • Patent number: 11104897
    Abstract: The present invention relates to compositions and methods for the treatment of nucleotide repeat expansion disorders such as myotonic dystrophy.
    Type: Grant
    Filed: April 27, 2016
    Date of Patent: August 31, 2021
    Assignees: GENETHON, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE D'EVRY VAL D'ESSONNE
    Inventors: Ana Maria Buj Bello, Mirella Lo Scrudato
  • Patent number: 11104913
    Abstract: The present invention concerns methods and approaches for modifying guanosine tetraphosphate (ppGpp) homeostasis in photosynthetic eukaryotes, in particular plants or algae, in order to modulate senescence for the remobilisation of nitrogen and other nutrients from the chloroplast, and modified photosynthetic eukaryotes thus produced.
    Type: Grant
    Filed: February 7, 2017
    Date of Patent: August 31, 2021
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITÉ D'AIX MARSEILLE
    Inventors: Benjamin Field, Matteo Sugliani, Christophe Robaglia, Hela Abdelkefi
  • Patent number: 11097715
    Abstract: Disclosed is a method for calculating a control setpoint of a hybrid powertrain of a motor vehicle, the hybrid powertrain including an electric motor and an internal combustion engine (ICE) that is equipped with a gearbox and that is supplied with fuel. The method includes: acquiring a value relative to a power requested at the vehicle's drive wheels; and determining the contribution of the electric motor and the ICE in order to satisfy the request for power at the drive wheels. The determination step involves calculating a triplet of three values, one value relating to the electromechanical power that the electric motor must provide, one value relating to the thermomechanical power that the ICE must provide and one value relating to the ratio that needs to be engaged in the gearbox, this triplet minimising the fuel consumption of the ICE and the current consumption of the electric motor.
    Type: Grant
    Filed: February 22, 2018
    Date of Patent: August 24, 2021
    Assignees: RENAULT S.A.S., UNIVERSITE D'ORLEANS
    Inventors: Souad Hadj-Said, Ahmed Ketfi-Cherif, Guillaume Colin
  • Patent number: 11091735
    Abstract: The present invention relates to a polyvalent culture medium for anaerobic bacteria under aerobic conditions in blood culture bottles. The present invention provides a polyvalent culture medium for culture in aerobic atmosphere of anaerobic bacteria or aerobic bacteria comprising a basal culture medium for bacteria characterized in that it further comprises a mixture of the following antioxidant compounds: sodium hydrosulphide (Na2S), L-cysteine, ascorbic acid, glutathione, catalase, ubiquinol and lipoic acid.
    Type: Grant
    Filed: August 1, 2018
    Date of Patent: August 17, 2021
    Assignees: FONDATION MEDITERRANEE INFECTION FACULTÉ DE MÉDECINE, UNIVERSITE D'AIX MARSEILLE, ASSISTANCE PUBLIQUE—HOPITAUX DE MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
    Inventors: Didier Raoult, Saber Khelaifia, Marion Bonnet
  • Patent number: 11087870
    Abstract: A system of tracing a dental prosthesis, the prosthesis including an electrical power source coupled with a radio-communications signals transmitter capable of assuming a weakly active state in which it periodically sends out signals at a first transmission frequency, and a highly active state in which it periodically sends out signals at a second, higher transmission frequency, and a presence sensor for sensing presence of the prosthesis in a mouth of a user, capable of delivering information on absence of the prosthesis in the mouth. The transmitter is configured to pass from the weakly active state to the highly active state when the sensor delivers information on absence of the prosthesis in the mouth. The system also includes a base forming a support of the dental prosthesis when not worn by a user, and the transmitter assumes the weakly active state on detecting the prosthesis in proximity to the base.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: August 10, 2021
    Assignees: UNIVERSITE D'ANGERS, CENTRE HOSPITALIER UNIVERSITAIRE D'ANGERS
    Inventors: Annick Barthelaix, Jocelyn Rio, Antoine Spiesser
  • Publication number: 20210198636
    Abstract: The invention relates to a pharmaceutical composition for targeting drug delivery including gene delivery to lung tissue, comprising at least a therapeutic drug or gene associated to a syncytin protein, and its use in the prevention and/or treatment of lung diseases, in particular in gene therapy of said diseases using lentiviral vector particles or lentivirus-like particles pseudotyped with syncytin protein.
    Type: Application
    Filed: October 19, 2018
    Publication date: July 1, 2021
    Applicants: Genethon, Institut National de la Santé et de la Recherche Médicale, Université d'Evry val d'Essonne
    Inventors: Anne Galy, Youna Coquin, Maxime Ferrand
  • Patent number: 11041876
    Abstract: A system for measuring the distance of an obstacle, in which an optical flow is measured radially while rotating along a circle in a plane intersecting the obstacle; and the distance of the obstacle is determined according to the amplitude of the optical flow, the radius of the circle, and the speed of rotation.
    Type: Grant
    Filed: October 5, 2017
    Date of Patent: June 22, 2021
    Assignees: UNIVERSITE D'AIX-MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Stephane Marie Vincent Viollet, Fabien Thierry Alain Colonnier, Erik Vanhoutte
  • Publication number: 20210161973
    Abstract: The present invention relates to an aqueous extract useful notably for the regeneration of human or animal cells, notably mammalian cells, comprising an aqueous extract free of any insoluble solid debris of ground planarian organisms having a regeneration capacity, containing at least the intracellular components of the cells of said organisms of a cell lysate of said cells of said organisms.
    Type: Application
    Filed: May 30, 2018
    Publication date: June 3, 2021
    Applicants: FONDATION MEDITERRANEE INFECTION, UNIVERSITE D'AIX MARSEILLE, ASSISTANCE PUBLIQUE - HOPITAUX DE MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
    Inventors: Eric GHIGO, Eric CHABRIERE, Michel DRANCOURT, Vincent BONNIOL
  • Patent number: 11014947
    Abstract: The present invention relates to a compound of formula (I) wherein: i is 0 or 1; j is 0 or 1; k is 0 or 1; R1 and R2 are in particular H, (C1-C12)alkyl, or a group of formula C(O)R; R is a, linear or branched, alkyl radical, comprising at least 19 carbon atoms; R3 is H and k=0 when j=1; or, when j=0, R3 is —C(O)R or -L-C(O)R; L, U and L? are linkers; wherein, when j=0, at least one of the groups R1; R2 and R3 comprises a radical R.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: May 25, 2021
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), CENTRE HOSPITALIER UNIVERSITAIRE DE MONTPELLIER, UNIVERSITE D'AUVERGNE, UNIVERSITE DE MONTPELLIER
    Inventors: Philippe Brabet, David Cia, Laurent Guillou, Christian Hamel, Claire Vigor, Thierry Durand, Céline Crauste, Joseph Vercauteren
  • Publication number: 20210146275
    Abstract: The present invention relates to the field of upgrading biomass, in particular algal biomass, and more specifically the present invention relates to a method for extracting water-soluble compounds from microalgae and/or cyanobacteria, as well as the product obtained by this method and the uses of same, in particular in the food industry or as food supplements.
    Type: Application
    Filed: June 15, 2018
    Publication date: May 20, 2021
    Applicants: ALGAMA, UNIVERSITÉ D'AVIGNON ET DES PAYS DE VAUCLUSE
    Inventors: Farid CHEMAT, Maryline ABERT VIAN, Léa VERNES, Thomas FELICE, Mathieu GONCALVES ALVES
  • Patent number: 11008374
    Abstract: The present relates to interleukin 15 (IL-15) antagonists and uses thereof, in particular for the treatment of autoimmune diseases and inflammatory diseases. In particular, the present invention relates to an IL-15 mutant polypeptide having the amino acid sequence as set forth in SEQ ID NO:1 wherein the leucine residue at position 45 is substituted by an aspartic acid residue, the asparagines residue at position 65 is substituted by a lysine residue and the leucine residue at position 69 is substituted by an arginine residue.
    Type: Grant
    Filed: December 12, 2018
    Date of Patent: May 18, 2021
    Assignees: INSERM (Institut National de la Santé et de la Recherche Médicale), Université de Nantes, Centre National de la Recherche Scientifique (CNRS), Université d'Angers
    Inventors: Yannick Jacques, Erwan Mortier, Agnes Quemener, Ariane Plet
  • Publication number: 20210139943
    Abstract: The present invention relates to a specific culture medium for the culture and selective isolation of an Enterococcus hirae bacterium consisting of nutrients other than sugars from a basic culture medium for the culture of enterococci without aesculin, comprising inhibitors of Gram-negative and Gram-positive bacteria other than enterococci and preferably at least one antifungal compound characterized in that it comprises: as inhibitor of Gram-positive bacteria other than enterococci, sodium chloride at a concentration of at least 20 g/L and not more than 60 g/L, and as the only sugar, mannitol, and as the only dye, an indicator dye that changes colour at a pH lower than the pH of said specific culture medium corresponding to the acidification of said specific is culture medium resulting from the consumption of mannitol.
    Type: Application
    Filed: May 30, 2018
    Publication date: May 13, 2021
    Applicants: FONDATION MEDITERRANEE INFECTION, UNIVERSITE D'AIX MARSEILLE, ASSISTANCE PUBLIQUE - HOPITAUX DE MARSEILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE)
    Inventors: Didier RAOULT, Saber KHELAIFIA, Marion BONNET
  • Patent number: 11006228
    Abstract: An implantable microphone for a middle ear prosthesis, includes an attachment system for fixing to a fixation bone close to an individual's middle ear; a cylindrical holding sheath, the sheath to be fixed to the fixation bone by the attachment system and having a suitable shape for extending from the fixation bone towards the ear ossicles of the individual; a coupler including a rod and an end piece of a suitable shape for bringing into contact with a point of the ear ossicles of the individual in a reversible manner; a sensor for converting a mechanical signal into an electrical signal, the sensor being secured to the coupler, supported by the cylindrical holding sheath and placed substantially in the extension of the axis of the cylinder; and a translation system for translation of the coupler along the axis of the cylinder, the translation system being housed in the sheath.
    Type: Grant
    Filed: December 23, 2016
    Date of Patent: May 11, 2021
    Assignees: UNIVERSITE D'AIX MARSEILLE, ASSISTANCE PUBLIQUE DES HÔPITAUX DE MARSEILLE, INSTITUT FRANAIS DES SCIENCES ET TECHNOLOGIES DES TRANSPORTS, DE L'AMÉNAGEMENT ET DES RÉSEAUX
    Inventors: Laurent Badih, Arnaud Philippe Deveze
  • Publication number: 20210123916
    Abstract: The invention relates to a method for diagnosing a cancer in a mammal in a need thereof. The method comprises the following steps: collecting a biological sample from said mammal; determining, from said biological sample, if the ADAMTSL5 gene is overexpressed; diagnosing a cancer from the determination of the overexpression of said gene. It also relates to a kit for determining an overexpression of the ADAMTSL5 gene in a biological sample obtained from a mammal, to a pharmaceutical composition comprising an agent targeting ADAMTSL5 or the ADAMTSL5 pathway as well as a pharmaceutically acceptable carrier for use in the treatment of a cancer, and to a use of an ADAMTSL5 mRNA or protein as a biomarker of cancer.
    Type: Application
    Filed: March 29, 2019
    Publication date: April 29, 2021
    Applicants: UNIVERSITE D'AIX-MARSEILLE (AMU), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
    Inventors: Flavio Maina, Maria Arechederra, Rosanna Dono, Timothy Mead, Suneel Apte
  • Publication number: 20210093881
    Abstract: This magnetic emission device includes an antenna and further includes means designed to select one of a plurality of predefined portions of the antenna and to connect the selected portion to a current-generating device in order both to cause the current to pass through the selected portion of the antenna so as to radiate a magnetic field, and to prevent the current from passing outside of the selected portion of the antenna.
    Type: Application
    Filed: April 16, 2019
    Publication date: April 1, 2021
    Applicants: Université d'Aix Marseille, Centre National de la Recherche Scientifique, Ecole Centrale de Marseille, Assistance Publique - Hôpitaux de Marseille, Multiwave Technologies AG
    Inventors: Stefan ENOCH, Redha ABDEDDAIM, Éric, Émile, David GUEDJ, Raphaëlle Richieri LE ROUZIC, Megdouda BENAMARA, Marie Coralie BULTOT, Michael KEFEDER, Tryfon ANTONAKAKIS, Elodie GEORGET-PARIS, Fouad FEZARI
  • Patent number: 10960042
    Abstract: A eutectic extraction solvent for extracting plant (e.g. vegetable) and/or animal and/or prokaryotic biological material, wherein the solvent is a clear, stable and fluid mixture comprising: (a) betaine or a hydrated form of betaine; (b) at least one hydrogen bond donor compound selected from the group consisting of polyols and organic acids; and (c) water with the proviso that the eutectic extraction solvent does not contain any exogenous sugar and/or amine salt and/or anion.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: March 30, 2021
    Assignees: UNIVERSITE D'AVIGNON ET DES PAY DE VAUCLUSE, NATUREX
    Inventors: Alexis Lavaud, Michael Laguerre, Simona Birtic, Anne Sylvie Fabiano Tixier, Marc Roller, Farid Chemat, Antoine Charles Bily