Patents Assigned to UNIVERSITÉ DE BORDEAUX
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Patent number: 11905253Abstract: The present invention relates the field of reducing CD95-mediated cell motility in a subject, in particular for their use in the reduction of CD-95 mediated cancer cell motility, the reduction of CD95-mediated lymphocyte motility and/or B cell maturation, or the treatment of B-cell tumors, in a subject. The inventors identified a novel family of compounds having the ability to disrupt CD95/PLC?1 interaction and to neutralize the CD95-mediated calcium signaling pathway and cell migration in human peripheral blood lymphocytes (PBLs) and Th17 cells.Type: GrantFiled: April 19, 2019Date of Patent: February 20, 2024Assignees: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE DE RENNES 1, CENTRE HOSPITALIER UNIVERSITAIRE DE BORDEAUX, INSTITUT BERGONIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE DE BORDEAUXInventors: Pierre Vacher, Patrick Legembre, Mickael Jean, Patrick Blanco, Pierre Van De Weghe
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Patent number: 11897813Abstract: A nanoporous carbon-loaded cement composite that conducts electricity. The nanoporous carbon-loaded cement composite can be used in a variety of different fields of use, including, for example, a structural super-capacitor as an energy solution for autonomous housing and other buildings, a heated cement for pavement deicing or house basement insulation against capillary rise, a protection of concrete against freeze-thaw (FT) or alkali silica reaction (ASR) or other crystallization degradation processes, and as a conductive cable, wire or concrete trace.Type: GrantFiled: October 25, 2022Date of Patent: February 13, 2024Assignees: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE BORDEAUXInventors: Roland J. M. Pellenq, Aikaterini Ioannidou, Nicolas Chanut, Thibaut Divoux, Renal Backov, Franz-Josef Ulm
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Patent number: 11883903Abstract: Disclosed is a method for cutting dielectric or semiconducting material with a laser. The method includes the following steps: emission of a laser beam including at least one burst of N femtoseconds laser pulses; spatial separation of the laser beam into a first split beam having a first energy, and respectively, a second split beam having a second energy; spatial concentration of energy of the first split beam in a first zone of the material, respectively, of the second split beam in a second zone of the material, the first zone and the second zone being separate and staggered by a distance dx; and adjustment of the distance between the first zone and the second zone in such a way as to initiate a straight micro-fracture oriented between the first zone and the second zone.Type: GrantFiled: July 25, 2017Date of Patent: January 30, 2024Assignees: AMPLITUDE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE BORDEAUX, ALPHANOV INSTITUT D'OPTIQUE D'AQUITAINEInventors: Konstantin Mishchik, John Lopez, Rainer Kling, Clémentine Javaux-Leger, Guillaume Duchateau, Ophélie Dematteo-Caulier
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Patent number: 11876002Abstract: A method for interconnecting components of an electronic system includes depositing a sintering solution onto a first component to form an interconnection layer, the sintering solution comprising a solvent, metal nanoparticles dispersed in the solvent, and a stabilizing agent adsorbed onto the nanoparticles. More than 95.0%, preferably more than 99.0% of the mass of the nanoparticles include a metal selected from silver, gold, copper and alloys thereof and have a polyhedral shape with an aspect ratio greater than 0.8. The method also includes eliminating, at least partially, the solvent from the layer to form an ordered agglomerate in which the nanoparticles are regularly disposed in three axes, the stabilizing agent binding them together and maintaining at least a portion of the nanoparticles at a distance from each other, debinding and sintering the layer, and depositing a second component in contact with the layer before or during debinding or sintering.Type: GrantFiled: September 2, 2021Date of Patent: January 16, 2024Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE BORDEAUX, INSTITUT POLYTECHNIQUE DE BORDEAUXInventors: Maxime Bronchy, Etienne Duguet, Céline Feautrier, Mona Treguer-Delapierre
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Patent number: 11866373Abstract: A method for coating fibers, includes desizing sized short fibers having an average length less than or equal to 5 mm, the short fibers being made of ceramic material or carbon, sieving the desized short fibers in order to separate them from any agglomerates of sized short fibers still present, introducing the desized and sieved short fibers into a reactor, and coating the short fibers in the reactor by chemical vapor deposition in a fluidized bed.Type: GrantFiled: August 25, 2021Date of Patent: January 9, 2024Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SAFRAN CERAMICS, UNIVERSITE DE BORDEAUXInventors: Arnaud Delehouze, Eric Bouillon, Amine El Mansouri, Nathalie Dominique Bertrand, Alain Jean-Michel Guette
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Patent number: 11871650Abstract: The invention relates to a composition comprising a blend of fluorinated electroactive polymers and having a dielectric permittivity that exhibits greater stability over the operating temperature range with respect to each polymer employed on its own. The invention also relates to formulations and films produced on the basis of said composition. The invention also relates to a field-effect transistor, at least part of the dielectric layer of which is composed of a blend of fluorinated electroactive polymers.Type: GrantFiled: August 7, 2018Date of Patent: January 9, 2024Assignees: ARKEMA FRANCE, UNIVERSITE DE BORDEAUX, INSTITUT POLYTECHNIQUE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Fabrice Domingues Dos Santos, Thibaut Soulestin, Damien Thuau, Georges Hadziioannou
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Patent number: 11858859Abstract: A method for treating a carbon or ceramic yarn includes forming a coating on the yarn in a reaction zone of a reactor by heating a segment of the yarn in the presence of a gas phase in a microwave field, wherein the gas phase includes a mixture of a diluent gas and a coating precursor in the vapor state, and wherein the gas phase is formed at least by introducing the diluent gas into the reactor and mixing the introduced diluent gas with the coating precursor in the reactor before the reaction zone.Type: GrantFiled: August 11, 2021Date of Patent: January 2, 2024Assignees: SAFRAN CERAMICS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE BORDEAUXInventors: Arnaud Delehouze, Pierre Fenetaud, Sylvain Lucien Jacques
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Patent number: 11809625Abstract: A method for controlling a limb of a virtual avatar by the myoelectric activities of a limb of an individual. The method includes a first step of calibrating and second step of moving the limb of the virtual avatar. Also, a system suitable for implementing the method for controlling a limb of a virtual avatar by the myoelectric activities of a limb of an individual.Type: GrantFiled: March 12, 2021Date of Patent: November 7, 2023Assignees: UNIVERSITÉ DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Christophe Halgand, Matthieu Guemann, Aymar Goullet De Rugy, Daniel Cattaert
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Patent number: 11807870Abstract: The invention relates to a cellular microcompartment comprising successively, organized around a lumen, at least one layer of pluripotent cells, an extracellular matrix layer and an outer hydrogel layer. The invention also relates to processes for preparing such cellular microcompartments.Type: GrantFiled: November 23, 2017Date of Patent: November 7, 2023Assignees: UNIVERSITE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT D'OPTIQUE THEORIQUE ET APPLIQUEEInventors: Maxime Feyeux, Kevin Alessandri, Pierre Nassoy, Laurent Cognet, Gaëlle Recher, Erwan Bezard
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Patent number: 11802336Abstract: The present disclosure relates to an apparatus for fluidised-bed chemical vapour deposition from a gaseous phase allowing the temperature of the fluidised bed to be stabilised during the deposition and also to an associated method for its implementation, the apparatus being characterised in that it comprises a porous thermal insulator present in an inlet zone and configured to be passed through by the gaseous phase, said porous thermal insulator having an effective thermal conductivity at 20° C. less than or equal to 3.5 W·m-1·K-1.Type: GrantFiled: June 21, 2021Date of Patent: October 31, 2023Assignees: SAFRAN CERAMIC, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE BORDEAUXInventors: Amine El Mansouri, Nathalie Dominique Bertrand, Sébastien Couthures, Alain Jean-Michel Guette
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Patent number: 11746065Abstract: A method for manufacturing a part made of composite material in which an adhesion promoter is grafted to a coating present on the fibre surface as well as to a ceramic precursor resin. Afterwards, a ceramic matrix phase is formed in the porosity of the fibre preform by pyrolysis of the polymerised resin.Type: GrantFiled: June 2, 2021Date of Patent: September 5, 2023Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SAFRAN CERAMICS, UNIVERSITE DE BORDEAUX, UNIVERSITE DE MONTPELLIER, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIERInventors: Nicolas Eberling-Fux, Marion France Hélène Schmidt, Samuel Jean-Charles Bernard
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Patent number: 11746060Abstract: A method for manufacturing a part made of composite material includes forming a ceramic matrix phase in pores of a fibrous preform by pyrolysis of a cross-linked copolymer ceramic precursor, the cross-linked copolymer including a first precursor macromolecular chain of a first ceramic having free carbon, and a second precursor macromolecular chain of a second ceramic having free silicon, the first macromolecular chain being bonded to the second macromolecular chain by cross-linking bridges including a bonding structure of formula *1—X—*2; in this formula, X designates boron or aluminium, -*1 designates the bond to the first macromolecular chain and -*2 the bond to the second macromolecular chain.Type: GrantFiled: June 2, 2021Date of Patent: September 5, 2023Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, SAFRAN CERAMICS, UNIVERSITE DE BORDEAUX, UNIVERSITE DE MONTPELLIER, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIERInventors: Marion France Hélène Schmidt, Samuel Jean-Charles Bernard, Nicolas Eberling-Fux
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Patent number: 11744003Abstract: Disclosed is a device for interaction between a laser beam and a hyperfine energy transition of a chemical species. The device further includes an electro-optic modulator with a single sideband with an input optical waveguide suitable for receiving a source laser beam and an output optical waveguide suitable for generating an output laser beam and an electronic system suitable for generating and applying, simultaneously, a first modulated electrical signal, sin(?1t)) to a first hyperfrequency pulse on a first high-frequency electrode of the electro-optic modulator and, respectively, another modulated electrical signal, cos(?1t)) to the first pulse on another high-frequency electrode of the electro-optic modulator, in such a way as to frequency-switch the output laser beam to a first optical frequency offset from the first pulse with respect to the initial optical frequency.Type: GrantFiled: November 22, 2018Date of Patent: August 29, 2023Assignees: EXAIL, INSTITUT D'OPTIQUE GRADUATE SCHOOL, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE BORDEAUXInventors: Henri Porte, Baptiste Battelier
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Patent number: 11713283Abstract: A part includes a substrate, having, adjacent to a surface of the substrate, at least a portion that is made from a material that contains silicon, and an environmental barrier formed on the surface of the substrate, the environmental barrier including at least a first layer including a rare earth disilicate of formula REa2Si2O7 present at a molar content lying in the range 70% to 99.9%, where REa is a rare earth element; and at least one rare earth oxide of formula REb2O3 present at a molar content lying in the range 0.1% to 30%, where REb is a rare earth element different from REa.Type: GrantFiled: January 4, 2018Date of Patent: August 1, 2023Assignees: SAFRAN CERAMICS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE BORDEAUXInventors: Lisa Pin, Simon Arnal, Francis Rebillat, Fabrice Mauvy
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Publication number: 20230234977Abstract: The present invention relates to a process for preparing a mixture M1 of enol phosphate isomers devoid of (E,E) isomer and comprising at least 98% of (E,Z) isomer, at least 0.1% of (Z,Z) isomer and at least 0.1% of (Z,E) isomer, comprising bringing a mixture of isomers of said enol phosphate comprising a detectable amount of (E,E) isomer into contact with a hydrolysable dienophile in an organic solvent, followed by base hydrolysis of the medium obtained and elimination of the adduct formed, in order to obtain the mixture M1 devoid of (E,E) isomer.Type: ApplicationFiled: April 3, 2023Publication date: July 27, 2023Applicants: Universite de Bordeaux, Institut Polytechnique de Bordeaux, Centre National de la Recherche Scientifique (CNRS)Inventors: Mathieu Pucheault, Virginie Liautard, Loic Guillonneau, Olivier Guerret
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Patent number: 11707881Abstract: A method for printing uses at least one bio-ink. The method also uses at least one laser print head to deposit at least one droplet of at least one bio-ink onto a depositing surface of a receiving substrate. The printing method uses at least one nozzle print head to deposit at least one droplet of at least one bio-ink onto a depositing surface of the same receiving substrate as the laser print head.Type: GrantFiled: April 13, 2021Date of Patent: July 25, 2023Assignees: Universite de Bordeaux, Institut National de la Sante et de la Recherche Medicale-lnsermInventor: Fabien Guillemot
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Patent number: 11707637Abstract: An ultrasound cardiac stimulation system includes: a system for measuring the heart electrical activity; a system for generating a beam of focussed ultrasound signals focussed on a targeted zone, the signals being calibrated to generate electrical stimulation in a zone of the heart, the beam generation being synchronised with a first selected time of the electrocardiogram, the generation of the beam corresponding to a pulse with a duration of less than 80 ms; a system for locating the targeted zone coupled with a system for positioning the system for generating the focussed beam to control the beam of focussed ultrasound signals in the targeted zone, the location system being synchronised with the system for generating the beam of focussed signals; a single monitoring system following in real time a temperature and tissue deformation in the targeted zone, the monitoring system taking measurements in synchronisation with the rhythm of the electrocardiogram.Type: GrantFiled: September 1, 2015Date of Patent: July 25, 2023Assignees: UNIVERSITE DE BORDEAUX, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, CENTRE HOSPITALIER UNIVERSITAIRE DE BORDEAUXInventors: Fabrice Marquet, Pierre Bour, Bruno Quesson, Fanny Vaillant, Remi Dubois
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Publication number: 20230193560Abstract: A method for obtaining a fibrous preparation for manufacturing a paper having significant water repellency and opacity in the dry or wet state. Fibres are suspended in water; calcium salts are added to the fibres; a source of carbonate salts in the form of an aqueous solution are added and the resulting mixture is stirred for a time sufficient to allow calcium carbonate particles to be precipitated. A solution of fatty acid salts heated to a temperature which corresponds to the micellisation temperature of said fatty acid salts is added and takes into account the critical micellar concentration of the fatty acid salts. The mixture is stirred thus obtained for a time sufficient to allow the fatty acids to be absorbed at the surface of the calcium carbonate particles and to obtain the desired fibrous preparation.Type: ApplicationFiled: March 27, 2021Publication date: June 22, 2023Applicants: PAPETERIE ZUBER RIEDER, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE BORDEAUX, INSTITUT POLYTECHNIQUE DE BORDEAUXInventors: Erwan LE GOUE, Véronique COMA, Stéphane GRELIER, Frédérique HAM-PICHAVANT
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Publication number: 20230193459Abstract: The present disclosure relates to an apparatus for fluidised-bed chemical vapour deposition from a gaseous phase allowing the temperature of the fluidised bed to be stabilised during the deposition and also to an associated method for its implementation, the apparatus being characterised in that it comprises a porous thermal insulator present in an inlet zone and configured to be passed through by the gaseous phase, said porous thermal insulator having an effective thermal conductivity at 20° C. less than or equal to 3.5 W·m-1·K-1.Type: ApplicationFiled: June 21, 2021Publication date: June 22, 2023Applicants: SAFRAN CERAMICS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE BORDEAUXInventors: Amine EL MANSOURI, Nathalie Dominique BERTRAND, Sébastien COUTHURES, Alain Jean-Michel GUETTE
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Publication number: 20230157994Abstract: A method of treating COVID-19 in a patient. The patient may be in moderate to advanced stages of COVID-19 infection. The method includes administering to the patient a therapeutically effective amount of at least one antagonist or inhibitor of chemokine receptor CXCR4. The at least one antagonist or inhibitor of chemokine receptor CXCR4 is distinct from hydroxychloroquine.Type: ApplicationFiled: May 5, 2021Publication date: May 25, 2023Applicants: 4LIVING BIOTECH, UNIVERSITE DE BORDEAUX, CENTRE HOSPITALIER DE BORDEAUX, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM, INSTITUT PASTEUR DE LILLE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ DE LILLEInventors: Patrick BERGER, Isabelle DUPIN, Renaud PREVEL, Chloé JAMES, Pierre-Olivier GIRODET, Keren BISMUTH, Revital RATTENBACH, Jérôme BRETON, Francois TROTTEIN, Valentin SENCIO