Abstract: Disclosed is a system for generating wavelength-tunable, ultra-short light pulses within the visible or infrared light spectrum. The system includes an injection module including a light source and a wavelength-tunable spectral filter. The light source is suitable for generating short light pulses, having a duration measured in nanoseconds, within an emission spectrum having a spectral width of several tens of nanometers to several hundred nanometers. The spectral filter has a spectral width between 250 pm and 3 nm and is suitable for spectrally and temporally filtering the short light pulses such that the injection module generates wavelength-tunable, spectrally filtered, ultra-short light pulses. The system also includes at least one optical amplifier suitable for generating wavelength-tunable, ultra-short, amplified pulses based on the wavelength of the spectral filter.
Type:
Grant
Filed:
December 24, 2015
Date of Patent:
April 2, 2019
Assignees:
UNIVERSITE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Eric Cormier, Jérome Lhermite, Romain Royon, Laurent Sarger
Abstract: The invention relates to bola-amphiphilic compounds and their uses for biomedical application. The invention particularly relates to the use of bola-amphiphilic compounds for providing low molecular weight gels (LMWG), useful, in particular, as culture media for animal or human cells, or as biocompatible material for biomedical applications.
Type:
Grant
Filed:
October 6, 2015
Date of Patent:
March 12, 2019
Assignees:
UNIVERSITE DE BORDEAUX, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM)
Inventors:
Philippe Barthelemy, Michael Ramin, Laurent Latxague, Ananda Appavoo, Olivier Chassande, Camille Ehret
Abstract: The invention relates to an antagonist of CB1 receptor for use in the treatment of a pathologic condition or disorder selected from the group consisting of bladder and gastrointestinal disorders; inflammatory diseases; cardiovascular diseases; nephropathies; glaucoma; spasticity; cancer; osteoporosis; metabolic disorders; obesity; addiction, dependence, abuse and relapse related disorders; psychiatric and neurological disorders; neurodegenerative disorders; autoimmune hepatitis and encephalitis; pain; reproductive disorders and skin inflammatory and fibrotic diseases.
Type:
Application
Filed:
October 24, 2018
Publication date:
March 7, 2019
Applicants:
INSERM (Institut National de la Santé et de la Recherche Médicale), UNIVERSITE DE BORDEAUX
Inventors:
Pier Vincenzo Piazza, Monique Vallee, Giovanni Marsicano, Francois-Xavier Felpin, Luigi Bellocchio, Daniela Cota, Jean-Michel Revest, Sergio Vitiello, Umberto Spampinato, Rafael Maldonado
Abstract: Optical fiber (1) made of a photosensitive glass and with a rectangular cross section, wherein the radius of curvature of a corner of the rectangular cross section is smaller than 100 microns.
Type:
Grant
Filed:
May 12, 2016
Date of Patent:
March 5, 2019
Assignees:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), Université de Bourgogne, Université de Bordeaux
Abstract: The invention relates to stable compositions of carbon nanotubes and of electrolytic polymers, these electrolytic polymers being characterized by the presence of phosphonyl imide or sulfonyl imide functions or alternatively phosphoric acid functions. The invention also relates to the manufacture of transparent electrodes comprising these compositions of carbon nanotubes and of electrolytic polymers.
Type:
Grant
Filed:
October 29, 2014
Date of Patent:
February 5, 2019
Assignees:
ARKEMA FRANCE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE BORDEAUX, INSTITUT POLYTECHNIQUE DE BORDEAUX
Inventors:
Christophe Navarro, Wiljan Smaal, Muhammad Mumtaz, Eric Cloutet, Cyril Brochon, Georges Hadziioannou
Abstract: The present invention relates to polypeptides and uses thereof for reducing CD95-meditated cell motility. In particular, the present invention relates to a polypeptide having an amino acid sequence having at least 70% of identity with the amino acid sequence ranging from the amino-acid residue at position 175 to the amino-acid residue at position 191 in SEQ ID NO:1.
Type:
Grant
Filed:
April 16, 2015
Date of Patent:
January 29, 2019
Assignees:
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE DE BORDEAUX, UNIVERSITE DE RENNES, ECOLE DES HAUTES ETUDES EN SANTE PUBLIQUE (EHESP), UNIVERSITE DES ANTILLES ET DE LA GUYANE, INSTITUTE BERGONIE, UNIVERSITY OF NOTTINGHAM
Inventors:
Patrick Legembre, Pierre Vacher, Doriane Sanseau, Aubin Penna, Robin Flynn
Abstract: Optical fiber (1) made of a photosensitive glass and with a rectangular cross section, wherein the radius of curvature of a corner of the rectangular cross section is smaller than 100 microns.
Type:
Application
Filed:
May 12, 2016
Publication date:
December 27, 2018
Applicants:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), Université de Bourgogne, Université de Bordeaux
Abstract: The present invention relates to methods and pharmaceutical compositions for the treatment of filovirus infections. In particular, the present invention relates to a method of treating filovirus infection in a subject in need thereof comprising administering the subject with a therapeutically effective amount of at least one oligonucleotide comprising the sequence as set forth in SEQ ID NO:1 to SEQ ID NO:15.
Type:
Grant
Filed:
March 10, 2016
Date of Patent:
December 25, 2018
Assignees:
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITÉ DE BORDEAUX
Abstract: The present invention relates to a process for preparing a compound having the formula (I), said process comprising the following steps: a) the addition of an oxygen source into a solution of a compound of formula (II), in a water-miscible solvent, b) the addition of a laccase in the solution obtained after step a); and c) the possible recovering of the compound of formula (I) thus obtained.
Type:
Grant
Filed:
October 5, 2015
Date of Patent:
December 18, 2018
Assignees:
UNIVERSITE DE BORDEAUX, INSTITUTE POLYTECHNIQUE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S)
Abstract: The invention relates to an antagonist of CB1 receptor for use in the treatment of a pathologic condition or disorder selected from the group consisting of bladder and gastrointestinal disorders; inflammatory diseases; cardiovascular diseases; nephropathies; glaucoma; spasticity; cancer; osteoporosis; metabolic disorders; obesity; addiction, dependence, abuse and relapse related disorders; psychiatric and neurological disorders; neurodegenerative disorders; autoimmune hepatitis and encephalitis; pain; reproductive disorders and skin inflammatory and fibrotic diseases.
Type:
Grant
Filed:
May 18, 2012
Date of Patent:
December 11, 2018
Assignees:
INSERM (Institut National de la Santé et de la Recherche Médicale), UNIVERSITE DE BORDEAUX
Inventors:
Pier Vincenzo Piazza, Monique Vallee, Giovanni Marsicano, Francois-Xavier Felpin, Luigi Bellocchio, Daniela Cota, Jean-Michel Revest, Sergio Vitiello, Umberto Spampinato, Rafael Maldonado
Abstract: The present invention relate to three dimensional porous polysaccharide matrices able to induce mineralization of a tissue in osseous site, as well as in non-osseous site, in the absence of stem cells or growth factors.
Type:
Grant
Filed:
July 24, 2017
Date of Patent:
December 4, 2018
Assignees:
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITE DE BORDEAUX II VICTOR SEGALEN, UNIVERSITÉ PARIS DIDEROT—PARIS 7
Inventors:
Joelle Amedee, Didier Letourneur, Catherine Le Visage, Sidi Mohammed Derkaoui, Jean-Christophe Fricain, Sylvain Catros
Abstract: Some embodiments are directed to a method and a device that allows fragile fibers, such as carbon fibers, for example, to be recycled so that they can be reused in a new form.
Type:
Grant
Filed:
October 30, 2015
Date of Patent:
November 6, 2018
Assignees:
UNIVERSITË DE BORDEAUX, INSTITUT POLYTECHNIQUE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Abstract: The present invention relates to a compound that may be obtained according to a method comprising at least one polymerization step of at least one monomer of formula (I) below: wherein the polymerization step is carried out in the presence of a catalyst selected from the group consisting of: Zn(OAc)2, Ti(OBu)4, Ti(OiPr)4, Sb2O3, stannous octanoate, dibutyltin oxide, 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene, NaOMe, 1,5,7-triazabicyclo[4.4.0]dec-5-ene and Lipase B Candida Antartica.
Type:
Application
Filed:
October 28, 2016
Publication date:
November 1, 2018
Applicants:
PIVERT, UNIVERSITÉ DE BORDEAUX, INSTITUT DES CORPS GRAS ETUDES ET RECHERCHES TECHN IQUES - ITERG, INSTITUT POLYTECHNIQUE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Blandine TESTUD, Etienne GRAU, Daniel TATON, Henri CRAMAIL, Didier PINTORI
Abstract: A method for analyzing a liquid sample, such as wine, in order to detect the possible presence of sulphite-resistant yeasts of the Brettanomyces bruxellensis species. The method includes detecting whether yeasts of the Brettanomyces bruxellensis species belonging to the genetic group of triploid oenological yeasts are found in the sample. If such yeasts are detected, then the sample is deduced to contain sulphite-resistant yeasts of the Brettanomyces bruxellensis species.
Type:
Application
Filed:
October 19, 2016
Publication date:
November 1, 2018
Applicants:
UNIVERSITE DE BORDEAUX, INSTITUT POLYTECHNIQUE DE BORDEAUX, ECOLE NATIONALE SUPERIEURE DES SCIENCES AGRONOMIQUES DE BORDEAUX AQUITAINE BORDEAUX SCIENC
Abstract: A method for printing uses at least one ink. The method includes: a step of focusing a laser beam so as to generate a cavity in an ink film; a step of forming at least one ink droplet from a free surface of the ink film; and a step of depositing the droplet onto a depositing surface of a receiving substrate positioned at a given distance from the film. The laser beam is oriented in the direction opposite the gravitational force. The free surface of the film is oriented upwards towards the depositing surface placed above the ink film.
Type:
Grant
Filed:
December 17, 2015
Date of Patent:
October 30, 2018
Assignees:
Université de Bordeaux, Institut National de la Sante et de la Recherche Medicale—Inserm
Abstract: The invention relates to methods and pharmaceutical compositions for the treatment of Ebola Virus Disease. In particular the present relates to a method of treating Ebola Virus Disease in a subject in need thereof comprising administering the subject with a therapeutically effective amount of Favipiravir.
Type:
Grant
Filed:
January 27, 2016
Date of Patent:
October 16, 2018
Assignees:
INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITÉ DE BORDEAUX, CHU DE BORDEAUX, TOYAMA CHEMICAL CO., LTD
Inventors:
Denis Malvy, Sylvain Baize, Xavier De Lamballerie, Hervé Raoul, Cédric Laouenan, Jeremie Guedj, France Mentre
Abstract: A polymer is provided having at least one repetitive unit represented by the following formula: And, preferably at least one, preferably at least two, repetitive units represented by the following formula:
Type:
Grant
Filed:
October 16, 2015
Date of Patent:
October 2, 2018
Assignees:
Pivert, Université de Bordeaux, Institut Des Corps Gras Etudes ET Recherches Techniques—ITERG, Institut Polytechnique de Bordeaux, Centre National de la Recherche Scientifique
Inventors:
Henri Cramail, Etienne Grau, Blandine Testud, Daniel Taton, Didier Pintori
Abstract: The invention pertains to a method of monitoring the membrane permeabilization of a liposome and the incidental release of a compound of interest. The method utilizes liposomes comprising a thermosensitive lipidic membrane encapsulating the product of interest and superparamagnetic nanoparticles having the electrostatic surface charge below ?20 mV or above +20 mV when measured in an aqueous medium at physiological pH. In one embodiment, the method comprises the steps of: a) measuring relaxation time (T2*); b) heating the liposome at Tm or above Tm; c) measuring T2* after step b); d) obtaining the transverse relaxivity (r2*) values from the T2* values obtained from step a) and step c); and e) determining the ratio of r2* before and after the heating step b). A ratio above 1.5 indicates the liposome membrane permeabilization and the incidental release of the product of interest.
Type:
Grant
Filed:
October 19, 2015
Date of Patent:
September 4, 2018
Assignees:
NANOBIOTIX, UNIVERSITE DE BORDEAUX, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Abstract: The invention relates to a method for controlling the movement of an Abrikosov vortex of an element consisting of a supraconductive material, a so-called supraconductive element, comprising a step of inhomogeneously heating the supraconductive element with the Abrikosov vortex in a heating zone in such a way as to move the Abrikosov vortex towards the heating zone.
Type:
Application
Filed:
August 23, 2016
Publication date:
August 30, 2018
Applicants:
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS, UNIVERSITE DE BORDEAUX
Inventors:
Alexandre Bouzdine, Brahim Lounis, Philippe Tamarat
Abstract: A method for depolymerization of lignin includes oxidizing non-phenolic lignin by putting into presence, in at least one solvent, non-phenolic lignin, laccase, redox mediator and a source of oxygen, whereby a mixture including oxidized non-phenolic lignin is obtained, and further includes depolymerization of the oxidized non-phenolic lignin thereby obtained, by adding an oxidizer. The non-phenolic lignin is obtained from phenolic lignin by functionalization of phenol functions of the phenolic lignin.
Type:
Grant
Filed:
November 26, 2014
Date of Patent:
August 28, 2018
Assignees:
Institut Polytechnique de Bordeaux, Université de Bordeaux, Centre national de la recherche scientifique