Abstract: Methods for the deposition of thin films comprising at least preparing a solution containing at least one transition metal oxide powder in a solvent, continuously stirring said solution in order to form a sol, and using said sol in the form of said transition metal oxide film, wherein the powder is subjected to a preliminary preparation step.
Abstract: The present invention provides a medicament comprising as active ingredient an inhibitor of Coll2-1 peptide activity and/or an inhibitor of Coll2-1NO2 peptide activity for use in the prevention and/or treatment of osteoarthritis. Further, the present invention provides a medicament comprising as active ingredient an inhibitor of Coll2-1 peptide activity and/or an inhibitor of Coll2-1NO2 peptide activity for use in the prevention and/or treatment of rheumatic and musculoskeletal diseases (RMDs).
Type:
Application
Filed:
June 16, 2017
Publication date:
November 9, 2017
Applicants:
Université de Liège, Université Paris Descartes, Assistance Publique Hopitaux de Paris, Institut National de la Santé et de la Recherche Médicale
Inventors:
Yves HENROTIN, Cécile LAMBERT, Didier BORDERIE, François RANNOU
Abstract: The invention relates to the identification of a biomarker whose abundance in biological sample is changed in subjects with osteoarthritis and/or other ageing-related diseases. The biomarker has applications in the diagnosis of osteoarthritis and/or other ageing-related diseases, in determining the prognosis for an individual diagnosed with osteoarthritis and/or other ageing-related diseases, and in monitoring the efficacy of treatment for osteoarthritis and/or other ageing-related diseases.
Type:
Grant
Filed:
February 27, 2009
Date of Patent:
July 8, 2014
Assignee:
Universitè de Liège
Inventors:
Yves Henrotin, Myriam Gharbi, Michelle Deberg, Edwin De Pauw
Abstract: The invention relates to a method of analyzing spectral data for the selection of a calibration model, relating spectra of a substance to a physical or chemical parameter of the substance, over a predetermined range of the physical or chemical parameter, comprising the steps: a) capturing spectral data of the substance with respective values of the physical or chemical parameter over the predetermined range, b) creating a plurality of calibration models using the captured spectral data in dependence upon the values of the physical or chemical parameter based on the calibration data using statistical resampling methods, c) calculating tolerance intervals of the results at each reference level for each calibration model, and d) displaying the tolerance intervals at each reference level over the predetermined range for each calibration model.
Type:
Grant
Filed:
May 6, 2009
Date of Patent:
July 23, 2013
Assignees:
Université de Liège, Arlenda s.a.
Inventors:
Philippe Hubert, Eric Ziemons, François Moonen
Abstract: Methods are described for improving the diagnostic possibilities of diseases where oxidative NO-modifications occur, for example inflammatory conditions, cancer, Parkinson's or Alzheimer's disease, and to provide means of monitoring the effects of therapeutical measures taken towards such diseases. The invention enables the detection of disease specific catabolic markers related to oxidative NO-modifications, utilizing an immunoassay comprising antibodies directed against nitrated and non-nitrated epitopes characteristic of a specific protein.
Type:
Grant
Filed:
August 30, 2011
Date of Patent:
December 11, 2012
Assignee:
Université de Liège
Inventors:
Jean-Yves Reginster, Michelle Deberg, Yves Henrotin, Stephan Christgau
Abstract: The present invention describes a method to improve the properties of a dough and/or a baked product by adding a bread or dough-improving agent containing a enzyme with xylanolytic activity belonging to glycoside hydrolases family 8. Preferred enzymes are the psychrophilic xylanase from Pseudoalteromonas haloplanktis and the mesophilic xylanase Y from Bacillus halodurans C-125.
Type:
Grant
Filed:
August 25, 2010
Date of Patent:
November 13, 2012
Assignee:
Université de Liège
Inventors:
Tony Collins, Georges Feller, Charles Gerday, Marie-Alice Meuwis
Abstract: A first object of the invention is a radiation detector comprising an energy absorber (203), for absorbing incident radiation (RAD) and thus undergoing a temperature increase; and optical readout means, for detecting said temperature increase; wherein said optical readout means comprises input coupling means (202) for coupling a light beam (2011) to said energy absorber (203) by exciting surface plasmons resonance, a surface plasmons resonance condition being dependent on the energy absorber (203) temperature, and wherein said energy absorber (203) is separated from said input coupling means (202) by a dielectric layer (2032).
Type:
Grant
Filed:
May 24, 2007
Date of Patent:
August 14, 2012
Assignee:
Université de Liège
Inventors:
Karl Fleury-Frenette, Serge Habraken, Yvon Renotte, Jurij Hastanin
Abstract: A lightweight and energetically autonomous device for real-time monitoring of overhead power lines, comprising:—an external housing (EMS1) provided, at opposed ends thereof, with a first (OP1) and a second (OP2) opening for a power line cable (HVC) traversing said external housing; a monitoring subsystem (B) for monitoring at least a mechanical parameter of said overhead power line; and—a communication subsystem (D) for transmitting monitoring information generated by said monitoring subsystem; characterized in that: an internal housing (EMS2) is provided within said external housing (EMS1), said power line cable (HVC) passing outside said internal housing (EMS2); said monitoring subsystem (B) is disposed within said internal housing (EMS2); said external (EMS1) and internal (EMS2) housings are both made of a conducting material in order to form electromagnetic shields; and said monitoring subsystem (B) comprises at least an oscillation sensor for detecting mechanical oscillations of said power line cable (HV