Abstract: A process for preparing an at least partially lithiated transition metal oxyanion-based lithium-ion reversible electrode material, which includes providing a precursor of said lithium-ion reversible electrode material, heating said precursor, melting same at a temperature sufficient to produce a melt including an oxyanion containing liquid phase, cooling said melt under conditions to induce solidification thereof and obtain a solid electrode that is capable of reversible lithium ion deinsertion/insertion cycles for use in a lithium battery. Also, lithiated or partially lithiated oxyanion-based-lithium-ion reversible electrode materials obtained by the aforesaid process.
Type:
Application
Filed:
September 14, 2012
Publication date:
January 10, 2013
Applicants:
UNIVERSITÉ DE MONTREAL, PHOSTECH LITHIUM INC., CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
LAURENT GAUTHIER, Michel Gauthier, Donald Lavoie, Christophe Michot, Nathalie Ravet
Abstract: Reagents, kits, uses and methods useful for example fo decreasing nonspecific adsorption of biomolecules at the surface of a solid support are disclosed. Such reagents and methods, which are based on short heteropeptides, may be used to decrease nonspecific adsorption in for example biosensing applications.
Type:
Application
Filed:
November 16, 2010
Publication date:
December 27, 2012
Applicant:
UNIVERSITE DE MONTREAL
Inventors:
Olivier Bolduc, Joelle N. Pelletier, Jean-François Masson
Abstract: A measurement device for measuring activity of the spinal cord of a vertebrate, wherein the device includes at least one main probe (1) shaped to be fastened to a spinous process (2) of a vertebra (3) and to hold in position on opposite sides of the vertebra at least one emitter (6) for emitting a wave capable of interacting with the spinal cord (7) and at least one associated receiver (8) for receiving the wave that has interacted with the spinal cord and for generating a signal representative of the activity of the spinal cord.
Type:
Application
Filed:
November 10, 2010
Publication date:
November 8, 2012
Applicants:
UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), UNIVERSITE DE MONTREAL, ECOLE POLYTECHNIQUE
Abstract: Methods, uses, agents and compositions useful for the diagnosis, prevention and/or treatment of inflammatory conditions, such as neuroinflammatory conditions such as multiple sclerosis, and for the identification and selection of inflammatory cytokine-secreting T cell or a precursor thereof, based on the expression and/or modulation of melanoma cell adhesion molecule (MCAM) are disclosed.
Type:
Grant
Filed:
June 9, 2010
Date of Patent:
October 23, 2012
Assignee:
Centre Hospitalier de l'Université de Montréal
Abstract: The invention relates to triazole salts, to their preparation and to applications thereof. The salts have at least one anionic triazolium group which carries at least one chlorosulphonyl, fluorosulphonyl or alkoxyfluorosulphonyl group, each of the anionic groups being combined with a proton or a cation that has a valency of less than or equal to 4. The salts are useful as synthesis reagents, as chemical-reaction or polymerization catalysts, and as ion-conducting materials for electrochemical generators, supercapacitors and electrochromic devices.
Type:
Application
Filed:
May 23, 2012
Publication date:
September 13, 2012
Applicants:
Universite De Montreal, Phostech Lithium Inc.
Abstract: The present invention concerns electrode materials capable of redox reactions by electron and alkali-ion exchange with an electrolyte. The applications are in the field of primary (batteries) or secondary electrochemical generators, supercapacitors and light modulating systems of the electrochromic type.
Type:
Grant
Filed:
October 6, 2010
Date of Patent:
September 4, 2012
Assignees:
ACEP Inc., Centre National de la Recherche Scientifique (“CNRS”), Universite de Montreal
Inventors:
Nathalie Ravet, Simon Besner, Martin Simoneau, Alain Vallee, Michel Armand, Jean-Francois Magnan
Abstract: The present invention concerns electrode materials capable of redox reactions by electron and alkali-ion exchange with an electrolyte. The applications are in the field of primary (batteries) or secondary electrochemical generators, supercapacitors and light modulating systems of the electrochromic type.
Type:
Application
Filed:
May 4, 2012
Publication date:
August 23, 2012
Applicants:
ACEP Inc., Universite De Montreal, CNRS
Inventors:
Nathalie Ravet, Simon Besner, Martin Simoneau, Alain Vallee, Michel Armand, Jean-Francois Magnan
Abstract: The present invention concerns electrode materials capable of redox reactions by electron and alkali-ion exchange with an electrolyte. The applications are in the field of primary (batteries) or secondary electrochemical generators, supercapacitors and light modulating systems of the electrochromic type.
Type:
Application
Filed:
May 4, 2012
Publication date:
August 23, 2012
Applicants:
ACEP Inc., Universite De Montreal, CNRS
Inventors:
Nathalie Ravet, Simon Besner, Martin Simoneau, Alain Vallee, Michel Armand, Jean-Francois Magnan
Abstract: Novel fluorescent markers of Formula I: are disclosed herein, wherein X and Y are independently or together absent or are independently selected from R and R1 are independently selected from H and alkyl; Ar is phenyl or heteroaryl; L is absent or a spacer selected from the group consisting of —NH—; —(CH2)nNH—; —NHSO2—; —(CH2)nNHCO—; -(cycloalkyl)NHCO—; —(CH2)nNHSO2—; -(cycloalkyl)NHSO2—; —CONH(CH2)nNHCO—; —CONH(cycloalkyl)NHCO—; —NHCO(CH2)nNHCO—; —NHCO(cycloalkyl)NHCO—; —(CH2)nSO2NH—; -(cycloalkyl)SO2NH—; —(CH2)nNHCSNH—; -(cycloalkyl)NHCSNH—; —CR?CR1—; —C?C—; —(CH2)nN?CH—; -(cycloalkyl)N?CH—; —N?CH(CH2)—; —N?CH(cycloalkyl)-; n is an integer ranging from 1 to 5; F is a fluorophore selected from the group consisting of fluorescein, rhodamine, eosin, thionine, safranin, coumarin, methoxycoumarin, dansyl, BODIPY and BODIPY derivatives; and wherein X, Y and L may be positioned in a 1,3,5; 1,2,3; 1,3,4 or in a 3,4,5 configuration respectively.
Abstract: The present application describes general process for the preparation of amino-substituted gamma-lactams involving the reaction of synthons of the general Formulae (I) and (VI): with amines. The processes are amenable to solid phase synthetic techniques and therefore allow the efficient incorporation of amino-substituted gamma-lactams into a wide variety of structural scaffolds, including, in particular peptides.
Type:
Application
Filed:
March 18, 2010
Publication date:
April 26, 2012
Applicant:
UNIVERSITE DE MONTREAL
Inventors:
William Lubell, Andrew Jamieson, Nicolas Boutard, Luisa Ronga, Daniel St-Cyr, Stephane Turcotte, Wang Chen
Abstract: A process for preparing an at least partially lithiated transition metal oxyanion-based lithium-ion reversible electrode material, which includes providing a precursor of said lithium-ion reversible electrode material, heating said precursor, melting same at a temperature sufficient to produce a melt including an oxyanion containing liquid phase, cooling said melt under conditions to induce solidification thereof and obtain a solid electrode that is capable of reversible lithium ion deinsertion/insertion cycles for use in a lithium battery. Also, lithiated or partially lithiated oxyanion-based-lithium-ion reversible electrode materials obtained by the aforesaid process.
Type:
Grant
Filed:
April 3, 2009
Date of Patent:
March 13, 2012
Assignees:
Universite de Montreal, Centre National de la Recherche Scientifique, Phostech Lithium Inc.
Inventors:
Laurent Gauthier, Michel Gauthier, Donald Lavoie, Christophe Michot, Nathalie Ravet
Abstract: A process for preparing an at least partially lithiated transition metal oxyanion-based lithium-ion reversible electrode material, which includes providing a precursor of said lithium-ion reversible electrode material, heating said precursor, melting same at a temperature sufficient to produce a melt including an oxyanion containing liquid phase, cooling said melt under conditions to induce solidification thereof and obtain a solid electrode that is capable of reversible lithium ion deinsertion/insertion cycles for use in a lithium battery. Also, lithiated or partially lithiated oxyanion-based-lithium-ion reversible electrode materials obtained by the aforesaid process.
Type:
Application
Filed:
August 25, 2011
Publication date:
February 2, 2012
Applicants:
UNIVERSITE DE MONTREAL, PHOSTECH LITHIUM INC., CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Laurent GAUTHIER, Michel Gauthier, Donald Lavoie, Christophe Michot, Nathalie Ravet
Abstract: The present invention relates to conjugated oligomers and polymers comprising aromatic thiophene cores. The conjugated materials are obtained by simple and efficient condensation of an aryl diamine and an aryl dialdehyde or a bifunctional aryl moiety comprising both an aldehyde and an amine. Condensation of the complementary moieties at temperatures ranging from ambient to refluxing temperatures in various solvents resulted in conjugated oligomers and polymers that can subsequently be cast into thin films. Oligomerization and polymerization can be done under mild conditions with removal of the resulting water bi-product responsible for shifting the equilibrium in favour of the conjugated products. The resulting conjugated compounds can be made conducting with dopants affording electrically conducting materials of either p-type or n-type conductors depending on the dopant selected.
Abstract: A surface plasmon resonance instrument and measuring method, in which a lens collimates light into a light beam, a prism propagates the collimated light beam at a single propagation angle and with internal reflection on a face of the prism, and an analyzer processes the collimated light beam from the prism. The face of the prism is configured to receive a surface plasmon resonance sensor and at least the first lens and the prism are aligned on a single optical axis.
Abstract: A device and method for evaluating or improving perceptual-cognitive abilities of a subject, comprising displaying virtual objects moving in a given three-dimensional environment during successive tests. The subject is in visual contact with the virtual objects moving in the three-dimensional environment, and the speed of movement of the virtual objects in the three-dimensional environment during the successive tests is changed.
Abstract: A process for preparing an at least partially lithiated transition metal oxyanion-based lithium?ion reversible electrode material, which includes providing a precursor of said lithium-ion reversible electrode material, heating said precursor, melting same at a temperature sufficient to produce a melt including an oxyanion containing liquid phase, cooling said melt under conditions to induce solidification thereof and obtain a solid electrode that is capable of reversible lithium ion deinsertion/insertion cycles for use in a lithium battery. Also, lithiated or partially lithiated oxyanion-based-lithium-ion reversible electrode materials obtained by the aforesaid process.
Type:
Grant
Filed:
November 23, 2010
Date of Patent:
November 1, 2011
Assignees:
Universite de Montreal, Centre National de la Recherche Scientifique, Phostech Lithium Inc.
Inventors:
Laurent Gauthier, Michel Gauthier, Donald Lavoie, Christophe Michot, Nathalie Ravet
Abstract: The present invention relates to conjugated oligomers and polymers comprising aromatic thiophene cores. The conjugated materials are obtained by simple and efficient condensation of an aryl diamine and an aryl dialdehyde or a bifunctional aryl moiety comprising both an aldehyde and an amine. Condensation of the complementary moieties at temperatures ranging from ambient to refluxing temperatures in various solvents resulted in conjugated oligomers and polymers that can subsequently be cast into thin films. Oligomerization and polymerization can be done under mild conditions with removal of the resulting water bi-product responsible for shifting the equilibrium in favor of the conjugated products. The resulting conjugated compounds can be made conducting with dopants affording electrically conducting materials of either p-type or n-type conductors depending on the dopant selected.
Abstract: The invention identifies Syngap1 dysfunctions as causative of mental retardation. Described are methods of detecting mental retardation and methods of detecting non-syndromic mental retardation (NSMR) in a human subject. Particular methods comprise sequencing a human subject's genomic DNA for comparison with a control sequence from an unaffected individual. Also described are probes, kits, antibodies and isolated mutated Syngap1 proteins.
Type:
Application
Filed:
November 9, 2009
Publication date:
September 22, 2011
Applicants:
Centre Hospitalier Universitaire Saint-Justine, Universite De Montreal, Centre Hospitalier De L'Universite De Montreal
Inventors:
Jacques Michaud, Fadi Hamdan, Guy Rouleau, Julie Gauthier
Abstract: A method for diagnosing the presence of hereditary spastic paraplegia (HSP) or predicting the risk of developing HSP in a human subject, comprising detecting the presence or absence of a defect in a gene encoding a polypeptide comprising the sequence of FIG. 9 (SEQ ID NO: 19), in a nucleic acid sample of the subject, whereby the detection of the defect is indicative that the subject has or is at risk of developing HSP.
Type:
Application
Filed:
May 18, 2011
Publication date:
September 8, 2011
Applicants:
Université de Montréal
Inventors:
Guy A. Rouleau, Paul Valdmanis, Inge Meijer, Pierre Drapeau, Patrick Dion
Abstract: The present invention relates to an injectable pharmaceutical composition with gelling properties containing:—an active principle; a hydrophobic and bio-compatible organic liquid; and an organogelling substance, the molecules of which have the capacity to bind together via bonds of low energy, wherein said organogelling substance is chosen among L-tyrosine derivatives responding to the following formula (I) wherein: R1 is an alkyl group containing 1 to 3 carbon atoms, linear or branched; and R2 is a hydrophobic group chosen among aliphatic saturated or unsaturated fatty chains or aryl or arylalkyl groups, Its use as a vector for the release of active principles, as well as its process of preparation.