Patents Assigned to Université de Paris
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Publication number: 20140179973Abstract: A process for metathesis of olefins, bringing olefins into contact with a catalyst activated by heating to a temperature in the range 100° C. to 1000° C. in an atmosphere of non-reducing gas, the catalyst containing at least one inorganic material having at least two elementary spherical particles, each of which are metal oxide particles with a size of at most 300 nm and containing at least one of tungsten, molybdenum, rhenium, cobalt, tin, ruthenium, iron or titanium, alone or a mixture, the metal oxide particles being present within a mesostructured matrix of an oxide of at least one element Y: silicon, aluminium, titanium, tungsten, zirconium, gallium, germanium, tin, antimony, lead, vanadium, iron, manganese, hafnium, niobium, tantalum, yttrium, cerium, gadolinium, europium or neodymium or a mixture thereof, the matrix having pore size 1.5 to 50 nm and amorphous walls with thickness 1 to 30 nm and maximum diameter of 200 ?m.Type: ApplicationFiled: July 11, 2012Publication date: June 26, 2014Applicants: UNIVERSITE DE PARIS 6 - PIERRE ET MARIE CURIE, IFP ENERGIES NOUVELLES, UNIVERSITE CATHOLIQUE DE LOUVAINInventors: Damien Debecker, Frederic Colbeau-Justin, Clement Sanchez, Alexandra Chaumonnot, Mikael Berthod
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Patent number: 8471070Abstract: The method for catalytic conversion of alcohols according to the present invention using a zinc oxide catalyst comprises a thermal pretreatment stage in an inert and/or reducing atmosphere at a temperature of at least 100° C., prior to the reaction stage.Type: GrantFiled: May 6, 2011Date of Patent: June 25, 2013Assignees: IFP Energies nouvelles, Centre National de la Recherche Scientifique, Universite de Paris 6—Pierre et Marie Curie Laboratoire Reactivite de SurfaceInventors: Charlotte Drouilly, Guylene Costentin, Helene Lauron-Pernot, Delphine Bazer-Bachi, Celine Chizallet, Vincent Lecocq
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Publication number: 20120134871Abstract: A hydridable alloy of formula R1-x-yMgxMyNis-aBa wherein R is selected from the group consisting in rare earths, yttrium and a mixture thereof; M represents Zr and/or Ti; B is selected from the group consisting in Mn, Al, Co, Fe and a mixture thereof; 0.1<x<0.4; 0?y<0.1; 3<s<4.5 and 0?a<1; at least 5% of the volume of which consists of a stack of sequences of a pattern of the A2B4 type and of n patterns of the CaCu5 type randomly distributed along one direction, n being an integer comprised between 1 and 10 and representing the number of patterns of the CaCu5 type per pattern of the A2B4 type. A method for making a hydridable alloy comprising steps for compression and applying a current through a mixture comprising Mg2Ni and a compound comprising nickel and one or several elements selected from the group consisting in rare earths and yttrium.Type: ApplicationFiled: November 28, 2011Publication date: May 31, 2012Applicants: SAFT, UNIVERSITE DE PARIS EST CRETEIL VAL DE MARNE UPEC, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Patrick BERNARD, Bernard KNOSP, Michel LATROCHE, Junxian ZHANG, Virginie SERIN, Martin HYTCH
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Publication number: 20110288342Abstract: The method for catalytic conversion of alcohols according to the present invention using a zinc oxide catalyst comprises a thermal pretreatment stage in an inert and/or reducing atmosphere at a temperature of at least 100° C., prior to the reaction stage.Type: ApplicationFiled: May 6, 2011Publication date: November 24, 2011Applicants: IFP ENERGIES NOUVELLES, UNIVERSITE DE PARIS 6 - PIERRE ET MARIE CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Charlotte DROUILLY, Guylene Costentin, Helene Lauron-Pernot, Delphine Bazer-Bachi, Celine Chizallet, Vincent Lecocq
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Patent number: 7838681Abstract: The invention relates to a method of synthesizing heterocyclic compounds. The invention is characterised in that it consists in opening a compound having formula (I), wherein: —X represents NH, O, S or a N-p group, p being a protective group, such as Boc or Troc; —Y represents N, O, S; —Z represents NH2 or NH-p; and —R1 represents a C1-C6 alkoxy radical, aryloxy, such as phenyloxy, or a pyrrolyl radical, said radicals being optionally substituted, or the salts thereof, and the isomers of the aforementioned compounds. Moreover, the above-mentioned opening step is performed in conditions such as to produce a heterocycle having formula (II), wherein: —X, Y and Z are as defined above; —R2 represents a —CH?CH—CH2—NH—COR1 or —CH?CH—CH2—NH—CO group; and R3 occupies one, two or three positions and represents a halogen. The invention can be used to synthesise natural products.Type: GrantFiled: April 30, 2004Date of Patent: November 23, 2010Assignees: Centre National de la Recherche Scientifique (C.N.R.S.), Universite de Paris SudInventors: Ali Al Mourabit, Nathalie Travert, Robert Abou-Jneid, Saïd Ghoulami
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Patent number: 7682635Abstract: A composition comprises an aqueous dispersion of particles (p) of mean hydrodynamic diameter between 50 and 5000 nm. The particles contain (A) polymers based on cyclodextrin units, comprising on average at least four cyclodextrin units within their structure; and (B) macromolecules of polysaccharides comprising groups G capable of forming inclusion complexes with the cyclodextrins present in the structure of the polymers (A), with an average number of groups G per polysaccharide macromolecule at least equal to three. The compounds (A) and (B) are water-soluble in the isolated state. A method is also provided which relates to the preparation of these compositions, as well as their use in order to achieve the encapsulation of compounds such as active substances.Type: GrantFiled: July 1, 2003Date of Patent: March 23, 2010Assignees: Centre National de la Recherche Scientifique (C.N.R.S.), Universite de Paris 11 - Paris SUDInventors: Ruxandra Gref, Catherine Amiel, Bernard Sebille, Patrick Couvreur
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Patent number: 7573029Abstract: A vacuum magnetic ion trap includes an assembly forming a permanent magnet including at least two magnetized structures (30, 32) in the form of hollow cylinders, one convergent radial structure, magnetized along a convergent radial direction, and one divergent radial structure, magnetized along a divergent radial direction, the convergent and divergent radial magnetized structures (30, 32) being arranged along a common longitudinal axis (XX?) The trap also includes a sealed chamber (4) containing anion confinement cell (8) fixed between the at least two magnetized structures (30, 32) and including at least two trapping electrodes (10) connectable to a voltage generator (12).Type: GrantFiled: August 2, 2005Date of Patent: August 11, 2009Assignees: Centre National de la Recherche Scientifique, Universite Pierre et Marie Curie-Paris VI, Universite de Paris 11 - Paris SudInventors: Michel Heninger, Joël Lemaire, Gérard Mauclaire, Pierre Boissel
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Patent number: 7479497Abstract: The invention relates to the use of 8-hydroxyquinoline 7-carboxylic acid derivatives in order to produce integrase-inhibiting medicaments, capable of blocking viral replication in the stages preceding integration, and if appropriate at the level of this integration stage, these medicaments being usable for the treatment of retroviral pathologies, in particular for the treatment of AIDS.Type: GrantFiled: May 15, 2003Date of Patent: January 20, 2009Assignees: Bioalliance Pharma SA, Institut Gustave Roussy, Centre National de la Recherche Scientifique (C.N.R.S.), Inserm, Universite de Paris 11- Paris SudInventors: Aurélie Mousnier, Catherine Dargemont, Sabine Bonnenfant, Hervé Leh, Jean-François Mouscadet, Fatima Zouhiri, Jean D'Angelo, Didier Desmaele
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Publication number: 20080296494Abstract: The invention concerns a vacuum magnetic ion trap comprising an assembly forming a permanent magnet including at least two magnetized structures (30, 32) in the form of hollow cylinders, one convergent radial structure, magnetized along a convergent radial direction, and one divergent radial structure, magnetized along a divergent radial direction, said convergent and divergent radial magnetized structures (30, 32) being arranged along a common longitudinal axis (XX?). Said trap also comprises a sealed chamber (4) containing an ion confinement cell (8) fixed between said at least two magnetized structures (30, 32) and including at least two trapping electrodes (10) connectable to a voltage generator (12).Type: ApplicationFiled: August 2, 2005Publication date: December 4, 2008Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S), UNIVERSITE PIERRE ET MARIE CURIE-PARIS VI TOUR CENTRALE, UNIVERSITE DE PARIS II PARIS SUDInventors: Michel Heninger, Joel Lemaire, Gerard Mauclaire, Pierre Boissel
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Patent number: 7298643Abstract: A magnetoresistive memory element including a trapped magnetic region and a free magnetic region separated by a barrier layer. The free magnetic region comprises a stacking of at least two antiferromagnetically-coupled ferromagnetic layers, a layer magnetic moment vector being associated with each layer, the resulting magnetic moment vector, equal to the sum of the layer magnetic moment vectors, having an amplitude smaller than at least 40% of the amplitude of the layer magnetic moment vector of maximum amplitude. The anisotropy field and/or the demagnetizing field tensor is not identical for the at least two ferromagnetic layers, whereby the angular deviations of the layer magnetic moment vectors are different at the time of the application of an external magnetic field, which enables at least two methods for directly writing into the memory element, as well as its initialization.Type: GrantFiled: April 25, 2005Date of Patent: November 20, 2007Assignees: STMicroelectronics SA, Centre National de la Recherche Scientifique, Universite de Paris SUD (Paris XI)Inventors: Joo-Von Kim, Thibaut Devolder, Claude Chappert, Cedric Maufront, Richard Fournel
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Publication number: 20050237796Abstract: A magnetoresistive memory element including a trapped magnetic region and a free magnetic region separated by a barrier layer. The free magnetic region comprises a stacking of at least two antiferromagnetically-coupled ferromagnetic layers, a layer magnetic moment vector being associated with each layer, the resulting magnetic moment vector, equal to the sum of the layer magnetic moment vectors, having an amplitude smaller than at least 40% of the amplitude of the layer magnetic moment vector of maximum amplitude. The anisotropy field and/or the demagnetizing field tensor is not identical for the at least two ferromagnetic layers, whereby the angular deviations of the layer magnetic moment vectors are different at the time of the application of an external magnetic field, which enables at least two methods for directly writing into the memory element, as well as its initialization.Type: ApplicationFiled: April 25, 2005Publication date: October 27, 2005Applicants: STMicroelectronics S.A., Centre National de la Recherche Scientifique, Universite de Paris Sud (Paris XI)Inventors: Joo-Von Kim, Thibaut Devolder, Claude Chappert, Cedric Maufront, Richard Fournel
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Patent number: 6663894Abstract: Compositions and methods for reducing ocular diseases by implanting in an eye of a subject a composition comprising encapsulated cells which produce polypeptides, more particularly polypeptides that exhibit neurotrophic and/or anti-angiogenic activity. The encapsulation prevents the entry of host immune cells in the microcapsule while permitting the release of the polypeptide outside of the microcapsule.Type: GrantFiled: February 1, 2001Date of Patent: December 16, 2003Assignees: Universite de Paris V Rene-Descartes, Association Francaise Retinitis PigmentosaInventors: Marc Abitbol, Yves Uteza, Maurice Menasche, Carine Bossard, Loic Van Den Berghe, Sebastian Bonnel, Hervé Prats, Jiri Honiger, Martin Neuner-Jehle
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Patent number: 6500449Abstract: Compositions and methods for reducing ocular diseases by implanting in an eye of a subject a composition comprising encapsulated cells which produce polypeptides, more particularly polypeptides that exhibit neurotrophic and/or anti-angiogenic activity. The encapsulation prevents the entry of host immune cells in the microcapsule while permitting the release of the polypeptide outside of the microcapsule.Type: GrantFiled: February 1, 2001Date of Patent: December 31, 2002Assignees: Universite de Paris V Rene-Descartes, Association Francaise Retinitis PigmentosaInventors: Marc Abitbol, Yves Uteza, Maurice Menasche, Carine Bossard, Loïc Van Den Berghe, Sébastian Bonnel, Hervé Prats, Jiri Honiger, Martin Neuner-Jehle
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Publication number: 20020076397Abstract: Compositions and methods for reducing ocular diseases by implanting in an eye of a subject a composition comprising encapsulated cells which produce polypeptides, more particularly polypeptides that exhibit neurotrophic and/or anti-angiogenic activity. The encapsulation prevents the entry of host immune cells in the microcapsule while permitting the release of the polypeptide outside of the microcapsule.Type: ApplicationFiled: February 1, 2001Publication date: June 20, 2002Applicant: Universite de Paris V Rene-DescartesInventors: Marc Abitbol, Yves Uteza, Maurice Menasche, Carine Bossard, Loic Van Den Berghe, Sebastian Bonnel, Herve Prats, Jiri Honiger, Martin Neuner-Jehle
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Publication number: 20020076396Abstract: Compositions and methods for reducing ocular diseases by implanting in an eye of a subject a composition comprising encapsulated cells which produce polypeptides, more particularly polypeptides that exhibit neurotrophic and/or anti-angiogenic activity. The encapsulation prevents the entry of host immune cells in the microcapsule while permitting the release of the polypeptide outside of the microcapsule.Type: ApplicationFiled: February 1, 2001Publication date: June 20, 2002Applicant: Universite de Paris V Rene-DescartesInventors: Marc Abitbol, Yves Uteza, Maurice Menasche, Carine Bossard, Loic Van Den Berghe, Sebastian Bonnel, Herve Prats, Jiri Honiger, Martin Neuner-Jehle
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Patent number: 6267954Abstract: Compositions and methods for reducing ocular diseases by implanting in an eye of a subject a composition encapsulated cells which produce polypeptides, more particularly polypeptides that exhibit neurotrophic and/or anti-anglogenic activity. The encapsulation prevents the entry of host immune cells in the microcapsule while permitting the release of the polypeptide outside of the microcapsule.Type: GrantFiled: November 24, 1999Date of Patent: July 31, 2001Assignees: Universite de Paris V Rene-Descartes, Association Francaise Retinitis PigmentosaInventors: Marc Abitbol, Yves Uteza, Maurice Menasche, Carine Bossard, Loïc Van Den Berghe, Sébastien Bonnel, Hervé Prats, Jiri Honiger, Martin Neuner-Jehle
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Patent number: 5116878Abstract: This medicinal composition for the treatment and prevention of the symptoms of heart failure contains, by way of active principle, at least one compound chosen from 2-amino-1-(2,5-dimethoxyphenyl)-1-propanol (methoxamine) and its pharmaceutically acceptable salts, and it is presented in a form which can be administered by inhalation (aerosol or nebulizate).It was demonstrated, in particular, that the administration of methoxamine-HCl by inhalation, at a unit dosage of 10 mg, in the form of a 2% (w/v) solution in physiological saline, decreases airways resistance in subjects suffering from decompensated left ventricular failure, and increases the exertion tolerance of patients suffering from compensated left vetricular failure, whether the latter is of ischemic origin or otherwise.Type: GrantFiled: June 14, 1989Date of Patent: May 26, 1992Assignee: Universite de Paris VInventors: Laure Cabanes, Alain Lockhart, Simon Weber
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Patent number: 4801849Abstract: An ion source is described, including a source of neutral particles which arrive at an ionization support positioned inside a chamber which is closed by a cap and which includes lateral walls. The cap includes an outlet orifice opposite which a plate defines a main ionization active surface. An electric field is applied between said device and by an electrode place downstream from the orifice in the direction of ion emission and fitted with a corresponding opening. Overall, the ionization support defines, by virtue of its active surface, and by virtue of holes surrounding said central active surface, a baffle assembly which prevents neutral atoms from passing directly to the outlet orifice, and which contributes to a high degree of ionization.Type: GrantFiled: November 6, 1987Date of Patent: January 31, 1989Assignees: Office National D Etudes et de Recherches, Aerospatiales and Universite de Paris-SudInventors: Georges Slodzian, Bernard Daigne, Francois Girard
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Patent number: 4638160Abstract: Between the electrostatic sector (SE 23) and the magnetic sector (SM 30) of a mass spectrometer, there is provided a quadrupole (QP 26) which applies parallel beams to the magnetic sector whose inclination depends on the energy dispersion of the particles. A slotted lens (LF 27) corrects the divergence of the quadrupole in the perpendicular plane. A suitable relationship between the angle of the inlet face of the magnetic sector (SM 30) and the deflection angle provided thereby ensures that the second order aperture aberrations of the magnetic sector are corrected. The chromatic aberrations may be corrected by means of a hexapole (HP 25) centered on the focus of the quadrupole (QP 26). Another hexapole (HP 22) placed upstream from the electrostatic sector (SE 23) level with a constriction in vertical section of the particle beam serves to correct second order aperture aberrations related to the electrostatic sector (SE 23).Type: GrantFiled: January 28, 1985Date of Patent: January 20, 1987Assignees: Office National d'Etudes et de Recherche Aerospatiales (ONERA), Universite de Paris-sudInventors: Georges Slodzian, Francois Costa De Beauregard, Bernard Daigne, Francois Girard