Abstract: A real-time measurement method of the sphygmic wave velocity (PWV) comprises an acquisition process (AQ) of sphygmic signals and a simultaneous analysis process (AN) of the acquired signals in real time, in which the analysis process involves searching for the foot of the sphygmic wave around a point corresponding to the relative minimum of the same band-pass filtered signal.

Abstract: The present invention relates to covalently cross-linked glycosylated mucin nanoparticles and the use thereof for the delivery and release of active ingredients, markers and/or biomolecules. The subject matter of the invention also relates to covalently cross-linked glycosylated mucin nanoparticles comprising at least one compound selected from an active ingredient, a marker and a biomolecule. The invention further relates to a method for preparing covalently cross-linked glycosylated mucin nanoparticles, optionally comprising at least one compound selected from an active ingredient, a marker and a biomolecule.

Abstract: A pesticide formulation includes an active ingredient, a substrate of a mineral origin and a biopolymer coating, wherein the active ingredient is adsorbed on a surface of the substrate and wherein the biopolymer coating covers the substrate, and the pesticide formulation is an herbicide formulation. A method for a production of the pesticide formulation and a method for a control of weeds by the herbicide formulation are provided. The pesticide formulation is advantageous applications for weeding agricultural areas, pasture areas, uncultivated areas and non-agricultural areas.

Abstract: A nucleic acid molecule encoding a chimeric chondroitin sulfate proteoglycan 4 (CSPG4) protein, wherein the chimeric CSPG4 protein comprises, from the N-terminal to the C-terminal: i) a first portion derived from the human CSPG4 sequence and a second portion derived from the canine CSPG4 sequence or ii) a first portion derived from the canine CSPG4 sequence and a second portion derived from the human CSPG4 sequence.

Abstract: A circuit arrangement for acquisition of signals from an apparatus for measuring beams of charged particles for external radiotherapy, in particular protons, carbon ions, and other ion species, emitted by particle accelerators, comprising at least one ionization-chamber sensor (10), which includes a plurality of sensor channels (20), said circuit arrangement (200; 500) comprising a plurality of channel branches (B0, . . . , B63; BR0, . . . , BR63) in parallel designed to be connected to said sensor channels (20) for receiving respective measurement signals (i) therefrom, said channel branches (B0, . . . , B63; BR0, . . . , BR63) comprising respective current-to-frequency converters (210) and counters (220) for supplying count values (CT), representing a charge associated to a given channel (20), to a multiplexer (250; 550). According to the invention, said channel branches (BR0, . . . , BR63) supply their own outputs (CT0, . . .

Abstract: Composition comprising chitosan for use in the prevention and/or treatment of incontinence and/or impotence in a subject undergoing prostatectomy.

Abstract: A system for signalling danger warnings arising from exposure of a subject to atmospheric pollutants, includes means for detecting environmental information in the proximity of the subject, and at least one personal mobile terminal. Sensor means are associated to the subject and configured for detecting one or more physiological parameters of the subject and supplying them to the personal mobile terminal. The system includes means for detecting the position of the subject and a data-processing module. The mobile terminal is configured for sending to the module local-detection data. The terminal is configured for receiving from the module danger warnings arising from exposure to pollutants calculated in the module and displaying to the subject the danger warnings or issuing alarms as a function of the values of the aforesaid danger warnings.

Abstract: The subject-matter of the invention is a food composition derived from ass's milk, which is useful in the feeding of premature babies, weak and/or delicate and/or convalescent subjects and/or the elderly.

Abstract: In one aspect, the invention relates to an inhibitor of the ?6 integrin/E-cadherin molecular complex for use as a medicament, in particular for the prevention or/and treatment of metastases of a primary cancer disease and a pharmaceutical composition or kit comprising as an active agent at least one of the inhibitors. In a further embodiment, the present invention relates to a method for determining the prognosis of metastatic homing of a primary cancer disease, in particular the aggressiveness of the metastatic potential of a primary cancer disease.

Abstract: The present invention concerns peptide sequences that specifically recognize cells of human hepatic metastases. The invention comprises also the use of nucleic acids coding for such peptides, as well as conjugates and formulations of such peptides for diagnostic and therapeutic purposes.

Abstract: A method for detecting human or animal blood traces on a surface is described. The method is fundamentally based on the reaction of luminol and includes the preliminary operation of atomizing an inorganic powder suspension, such as titania, silica, alumina, hydroxyapatite, or the like, onto the surface to be investigated, after which a composition of luminol, a peroxidic oxidizing agent and an alkaline agent in an amount providing a pH within the range of 10 to 14, is atomized on the surface. A kit for carrying out the detection method of the invention is also described.

Abstract: A silane-modified cyanine of Formula (I) includes the valence tautomers thereof: wherein R1 is a linear, saturated or unsaturated alkyl chain, having 1 to 30 carbon atoms, wherein one or more carbon atoms are optionally substituted by a 4-, 5- or 6-membered aromatic or non aromatic cyclic grouping of carbon atoms; R8 and R9 are independently selected from the group consisting of —OCH3, —OCH2CH3, —OCH2CH2CH3, —OCH(CH3)2, —OCH2CH2OCH3, —Cl, —Br, —I, Formula (II), Formula (III), —N(CH3)2, Formula (IV), Formula (V), methyl, ethyl, propyl, isopropyl. The synthesis method and the use as a fluorescent marker are for inorganic solid supports, for example silica nanoparticles, and/or for biomolecules such as peptides, antibodies, DNA, RNA, etc.

Abstract: Compounds of Formula (I): able to inhibit kinase activity, in particular Phosphatidylinositol 3-Kinases activity. The disclosure also relates to the use of compounds of Formula (I) for treatment of pathological conditions associated to alterations in Phosphatidylinositol 3-Kinases activity.

Abstract: A bone cement comprising an acrylic polymeric component and an inorganic component comprising a bioactive glass or glass-ceramic, comprising at least one metal oxide having an anti-bacterial activity, wherein said glass or glass-ceramic component is adapted to release ions of said metal in contact with physiological fluids. The bone cement performs a sustained antibacterial action, also promoting binding with the tissues with which it is contacted, and it is advantageously employed in the fixation of orthopaedic prostheses, in the production of temporary prostheses and in spinal surgery.

Abstract: We describe the use of PI3K? protein and/or its encoding gene for the screening for substances useful in the treatment of cancers, preferably breast cancers, as well as a method for the diagnosis of malignant cell growth comprising the measuring the expression of PI3K?. We also describe non-human transgenic animals as models for studying human pathologies, preferably breast cancer, being transgenic for having altered PI3K? and Neu-T expression.

Abstract: The present invention concerns peptide sequences that specifically recognize cells of human hepatic metastases. The invention comprises also the use of nucleic acids coding for such peptides, as well as conjugates and formulations of such peptides for diagnostic and therapeutic purposes.

Abstract: A method for detecting human or animal blood traces on a surface is described. The method is fundamentally based on the reaction of luminol and includes the preliminary operation of atomizing an inorganic powder suspension, such as titania, silica, alumina, hydroxyapatite, or the like, onto the surface to be investigated, after which a luminol composition is atomized thereon, which comprises a luminol compound, a peroxidic oxidising agent and an alkaline agent in an amount providing a pH within the range of 10 to 14. Furthermore, a kit for carrying out the detection method of the invention is described.

Abstract: Use of a fungal biomass for treating industrial wastewaters containing at least one dye and related method, wherein: i. the fungal biomass contains at least the fungal species Rhizomucor pusillus (Lindt) Schipper; ii. the fungal biomass absorbs the at least one dye, so as to obtain wastewater that is basically free of the at least one dye.

Abstract: It is generally accepted that salivary components are important for dental health, but till now no clear correlation has been found between one or more of said components and the onset of dental caries. The present invention relates to an assay method comprising analysing the presence and/or the content of the salivary soluble CD14 protein from a saliva sample of the individual subjected to examination; the absence of said protein from the salivary sample, or its presence in a reduced amount compared to a predetermined threshold value in caries-free individuals, is considered as a marker of susceptibility to developing caries and/or as a diagnostic element for the existence of ongoing carious lesions.

Abstract: Use of a fungal biomass for treating industrial wastewaters containing at least one dye, wherein: i. the fungal biomass contains at least the fungal species Cunninghamella elegans Lendner; ii. the fungal biomass absorbs the at least one dye, so as to obtain wastewater that is basically free of the at least one dye.