Abstract: A pharmaceutical formulation of a pharmaceutically active protein including an effective amount of a protein or a combination of proteins, a chitosan A and at least one statistic polysaccharide B. Also, a kit including the at least one first container containing the chitosan A and the statistic polysaccharide B and at least one second container containing the protein or combination of proteins. Further, the pharmaceutical formulation or the kit for use in the treatment of cancer, typically breast or gastric cancer.

Abstract: An optical device suitable for transmitting/reflecting electromagnetic radiation in a wavelength range of the electromagnetic spectrum. The device comprises at least a first coating layer made of a first material, a substrate made of a material different from the first material, and surface texturing forming cavities in the device. A lower layer, disposed directly below the first coating layer, is either a second coating layer made of a material different from the first material or the substrate itself. The lower layer has a predetermined thickness. The optical device has cavities that extend through the first coating layer and are sunk into the lower layer through at least part of its thickness. This structure enhances the optical properties of the device for specific applications in electromagnetic radiation transmission or reflection.

Abstract: Process of grafting of a polyethylene-containing material to produce a modified polyethylene composition comprising providing a twin screw extruder with one or more thermal regulation devices; a polyethylene-containing material and a grafting agent and extruding the polyethylene-containing material and the grafting agent to obtain a modified polyethylene composition; the step of extruding comprises a thermal treatment of the polyethylene-containing material by self-heating of the material at a maximum barrel temperature Ts ranging from 315° C. to 410° C. in one or more hot zones of the extruder.

Abstract: Embodiments of the disclosure relate to a composition including 70 to 95 parts by weight of an epoxide resin having a viscosity of between 1 and 150 kPa·s at a temperature of between 20° C. and 25° C., and 5 to 30 parts by weight, per 100 parts by weight of resin present in the composition, of a curing agent dispersed in the resin, the curing agent being an ionic liquid containing a phosphonium cation. The disclosure also relates to a semi-finished product or towpreg, including a bundle of fibres and a composition. The disclosure also relates to the use of a composition or of a semi-finished product according to the disclosure for the production of a hydrogen tank, in particular a type IV pressure tank, made of composite material, for the on-board storage of hydrogen gas.

Abstract: The invention relates to an electrically insulating composite material (1) comprising a polyepoxide matrix (2) of cycloaliphatic type or of diglycidyl ether type in a content of less than 40% by mass, from 20 to 75% by mass of one or several micrometric and/or mesometric filler(s) (3), and from 0.1 to 20% by mass of at least one ionic liquid (4), the masses being expressed relative to the total mass of the electrically insulating composite material (1). The invention also relates to a method for manufacturing such an electrically insulating composite material (1), as well as its use for an electrically insulating support (9) in a metal-enclosed substation (5).

Abstract: A device for medical imaging by X-ray is provided. More specifically, it relates to the simulation of the deployment of an endoprosthesis in order to assist the surgeon in an endovascular surgical procedure. The invention makes use of a single 2D image in order to determine certain characteristics of a simplified model of the endoprosthesis: 2D positions, and deployment value of the stents; to determine the inherent rotation of at least one stent; then to determine the deployment of a model representing the structure of the stents, initialized on the basis of the preceding steps, in a 3D model of a vascular structure.

Abstract: A fenestrated endoprosthesis of the thoracic aorta including a first mesh of stents, a main tubular endoprosthesis made of fabric, the main tubular endoprosthesis being rigidly attached to the first mesh, and having an arcuate central portion configured to be received in the aortic arch of a patient, the arcuate central portion extending between a first and a second end, each configured to be received respectively in a portion of the ascending or descending aorta, respectively. The fenestrated endoprosthesis further includes a flange also made of fabric and associated with a second mesh of stents, the flange having a substantially frustoconical shape and having a base, the base of the flange being mounted on an opening made in the upper face of the arcuate central portion, the flange being configured to be received at the base of the supra-aortic trunks of the patient.

Abstract: The invention relates to a process for nanostructuring the surface of a solid material in order to form a regular pattern of nanostructures on said surface, comprising: irradiating the surface by a plurality of pulse trains (20) of a femtosecond laser beam: each pulse train (20) comprises at least two pulses (21, 22), each pulse has a peak fluence, and a sum of the peak fluences of the pulses of a pulse train is between 10% and 70% of a threshold fluence corresponding to a material ablation threshold for one pulse for said material, two consecutive pulses of a pulse train are separated by a peak-to-peak duration ?T between 500 fs and 150 ps, two consecutive pulse trains are separated by a duration greater than 10 ?T, obtaining a regular pattern of nanostructures on said portion of surface, having a spatial periodicity lower than 130 nm.

Abstract: Silicone material obtained by a reaction between:—at least one organopolysiloxane (A) that has a molar mass of less than 70,000 g/mol, preferably less than 50,000 g/mol, and contains siloxyl units I.1 and I.2; and—at least one organic compound (B) carrying at least two carboxylic acid groups and having no unsaturation. Y a ? Z b 1 ? SiO 4 - ( a + b ) 2 ( I ? .1 ) Z c 2 ? SiO 4 - c 2 ( I ? .

Abstract: The present disclosure relates to a method for the preparation, from a mixture comprising (i) plant proteins, (ii) one or more plant tanning agents, (iii) one or more plasticizers, of a biobased material that may resemble animal leather.

Abstract: The present invention is related to a method for processing a question in natural language received at a server (2), comprising performing by a processing unit (21) of the server (2) steps of: (a) for each n-gram of the question which is not a stop word, from at least one given knowledge base of entities linked by relations, identifying as initial entities and initial relations the entities and relations of the knowledge base matching said n-gram; (b) generating a set of possible queries for entities or relations of said given knowledge base, as a function of the initial entities and initial relations identified for all the n-gram of the question; (c) ranking each query of said set of possible queries as a function of at least one predetermined criterion, so as to identify a top-ranked possible query; (d) executing said top-ranked possible query, and returning the result entities or relations.

Abstract: The present invention relates to apparatus for cutting out a human or animal tissue, such as a cornea, or a lens, said apparatus including a treatment device for producing a pattern consisting of at least two impact points in a focusing plane from a L.A.S.E.R. beam generated by a femtosecond laser (1), the treatment device being positioned downstream from said femtosecond laser, remarkable in that the treatment device comprises an optical focusing system (5) for focusing the L.A.S.E.R. beam in a cutting-out plane, and a control unit (6) able to control the displacement of the optical focusing system along an optical path of the L.A.S.E.R. beam for displacing the focusing plane in at least three respective cutting-out planes so as to form a stack of surfaces for cutting out the tissue.

Abstract: A focus adjustment method for acquiring an image of a surface of interest of a sample by a holographic imager includes the steps of: placing the sample including at least one reference object having a known shape and described by characterising parameters having at least position parameters acquiring an image and determining the position of the reference object with respect to the acquisition plane, by applying a light diffraction model involving the spatial parameters of the reference object estimated by approximating the appearance of the reference object in the holographic image acquired, and determining the position of the surface of interest with respect to the acquisition plane from a position of the reference object and focus adjustment of the image acquisition.

Abstract: The present invention relates to an optical device (1) suitable for transmitting/reflecting electromagnetic radiation in a wavelength range of the electromagnetic spectrum, said device (1) comprising at least: a first coating layer (10) made of a first material, a substrate (50) made of a material that is different from the first material, and surface texturing (60) forming cavities (61) in the device (1); wherein a lower layer (50) disposed directly below the first coating layer (10) is either a second coating layer (20) made of a material that is different from the first material, or the substrate (50); wherein the lower layer (50) has a determined thickness (E50); characterised in that the cavities (61) extend through the coating layer (20) and are sunk into the lower layer (50) through at least part of the thickness (E50).

Abstract: The present invention relates to an optical device (1), suitable for transmitting/reflecting electromagnetic radiation in a wavelength range of the electromagnetic spectrum, said device (1) comprising at least: a substrate (10) made of a first material, a coating layer (20) made of a second material that is different from the first material, and surface texturing (30) forming cavities (31) in the device (1), characterized in that the cavities (31) extend through the coating layer (20) and are partially sunk into the substrate (10).

Abstract: The present invention relates to an apparatus for cutting-out including a device for treating a L.A.S.E.R. beam generated by a femtosecond laser (1), and positioned downstream from said femtosecond laser, the treatment device comprising: a shaping system (3) positioned on the trajectory of said beam, for modulating the phase of the wave front of the L.A.S.E.R. beam according to a modulation set value calculated for distributing the energy of the L.A.S.E.R. beam in at least two impact points forming a pattern in its focal plane, an optical focusing system (5) downstream from the shaping system, the optical focusing system comprising a concentrator module for focusing the phase-modulated L.A.S.E.R.

Abstract: The invention relates to a device for olfactory stimulation of a patient with a plurality of scents, said device comprising: —a source (2) of a carrier gas (G); —a plurality of scent odorization circuits, each odorization circuit (4) comprising: —a container (18) containing an odorous volatile substance (V), —a container inlet line (26), provided with a container inlet valve (28), connecting an inlet (30) of said container with said source of carrier gas, and —a container outlet line (36), provided with a container outlet valve (38), connecting an outlet (40) of said container with an exit line (12); —a control unit (8), configured to control said container inlet valve and container outlet valve according to a medical protocol.

Abstract: A device for cutting human or animal tissue including a femtosecond laser that can emit a L.A.S.E.R. beam in the form of impulses. The device directs and focuses the beam onto or into the tissue for the cutting thereof. The device further includes and element to shape the L.A.S.E.R. beam, positioned in the trajectory of the beam, and to modulate the energy distribution of the L.A.S.E.R. beam in the focal plane thereof, corresponding to the cutting plane.

Abstract: A method for building a security image for a security structure of a security document from multiplexing color images, including selecting a marking method capable of producing sets of colors on the security document comprising different colors that can be displayed according to illumination/observation modes of the security structure, establishing a plurality of color sets that can be displayed by the security structure in a plurality of the different illumination/observation modes, distributing the color sets in a plurality of groups of color sets, establishing combinations of groups of color sets having at least one color set in common across the number of different illumination/observation modes, selecting a combination of a group of color sets based on the number of desired illumination/observation modes and the number of colors per color image, and determining the color images to multiplex by means of the combination of the group of color sets selected.

Abstract: The present invention relates to apparatus for cutting out a human or animal tissue, such as a cornea, or a lens, said apparatus including a treatment device for producing a pattern consisting of at least two impact points in a focusing plane from a L.A.S.E.R. beam generated by a femtosecond laser (1), the treatment device being positioned downstream from said femtosecond laser, remarkable in that the treatment device comprises an optical focusing system (5) for focusing the L.A.S.E.R. beam in a cutting-out plane, and a control unit (6) able to control the displacement of the optical focusing system along an optical path of the L.A.S.E.R. beam for displacing the focusing plane in at least three respective cutting-out planes so as to form a stack of surfaces for cutting out the tissue.