Abstract: The inventive imaging method consists in generating a mechanical wave having shearing and compressional components in a viscoelastic medium and in determining the movement parameter of said viscoelastic medium at different points during the propagation of said mechanical wave. Said method comprises a correction stage when the movement parameter is processed for eliminating errors caused by the compressional component of the mechanical wave.
Type:
Grant
Filed:
March 30, 2006
Date of Patent:
April 24, 2018
Assignees:
Centre National de la Recherche Scientifique—CNRS, Universite Paris 7—Denis Diderot 2
Inventors:
Mathias Fink, Ralph Sinkus, Mickaël Tanter, Jeremy Bercoff
Abstract: The present invention relates to a method for preparing a porous scaffold for tissue engineering. It is another object of the present invention to provide a porous scaffold obtainable by the method as above described, and its use for tissue engineering, cell culture and cell delivery. The method of the invention comprises the steps consisting of: a) preparing an alkaline aqueous solution comprising an amount of at least one polysaccharide, an amount of a cross-linking agent and an amount of a porogen agent b) transforming the solution into a hydrogel by placing said solution at a temperature from about 4° C. to about 80° C. for a sufficient time to allow the cross-linking of said amount of polysaccharide and c) submerging said hydrogel into an aqueous solution d) washing the porous scaffold obtained at step c).
Type:
Grant
Filed:
October 10, 2008
Date of Patent:
December 20, 2016
Assignees:
INSERM (Institut National de la Santé et de la Recherche Médicale), Université Paris 7—Denis Diderot
Abstract: The present invention relates to a method for preparing a porous scaffold for tissue engineering. It is another object of the present invention to provide a porous scaffold obtainable by the method as above described, and its use for tissue engineering, cell culture and cell delivery. The method of the invention comprise the steps consisting of a) preparing an alkaline aqueous solution comprising an amount of at least one polysaccharide and one cross-linking agent b) freezing the aqueous solution of step a) c) sublimating the frozen solution of step b). characterized in that step b) is performed before the cross-linking of the polysaccharide occurs in the solution of step a).
Type:
Grant
Filed:
October 10, 2008
Date of Patent:
May 12, 2015
Assignees:
INSERM (Institut National de la Sante et de la Recherche Medicale), Universite Paris 7—Denis Diderot
Inventors:
Catherine Le Visage, Didier Letourneur, Frederic Chaubet, Aude Autissier
Abstract: The invention pertains to the field of membrane protein immobilization onto supports. It relates to a product comprising a support and at least one membrane protein attached to the surface thereof, characterized in that said membrane protein is attached to said support using an amphiphilic molecule with which said membrane protein is complexed. It also relates to a process for preparing such product, as well as to various applications in the fields of diagnosis, drug design and biotechnologies. It further relates to a kit, together with a functionalized amphiphilic molecule, for preparing a product according to the invention comprising a support and an amphiphilic molecule, wherein the amphiphilic molecule and the support interact through a hydrophobic bond, an ionic bond, a specific bond or a covalent bond.
Type:
Grant
Filed:
November 13, 2007
Date of Patent:
June 26, 2012
Assignees:
Centre National de la Recherche Scientifique (CNRS), Universite Paris 7—Denis Diderot
Abstract: The use of at least one diazonium salt bearing an initiator function, for forming an undercoat obtained by grafting a graft derived from the diazonium salt and bearing an initiator function at the surface of a conductive or semiconductive material on the undercoat, and for forming on the undercoat a polymeric layer obtained by polymerization, in particular free radical polymerization, in situ of at least one monomer, initiated from the initiator function.
Type:
Grant
Filed:
June 2, 2005
Date of Patent:
November 8, 2011
Assignees:
Universite Paris 7—Denis Diderot, Alchimedics
Inventors:
Mohamed Mehdi Chehimi, Jean Pinson, Bernadette Charleux, Christophe Bureau, Christopher Tronche, Tarik Matrab, Christian Perruchot, Eva Cabet-Deliry, Maud Save