Patents Assigned to Université Paris-Sud 11
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Publication number: 20230192772Abstract: Peptides endowed with an anti-inflammatory, anti-angiogenic and/or antimicrobial activity, a medicament or a pharmaceutical composition including such peptides, and the use thereof in the prevention or treatment of inflammatory diseases, and more particularly inflammatory diseases due to or associated with microbial infections, or in the prevention or treatment of angiogenesis-related diseases.Type: ApplicationFiled: December 22, 2017Publication date: June 22, 2023Applicants: SORBONNE UNIVERSITE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITÉ PARIS-SUD 11, UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICOInventors: Claire LACOMBE, Constance AUVYNET, Yvonne ROSENSTEIN, Emmanuelle SACHON
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Patent number: 11162095Abstract: The present invention relates to the combination of a PARP inhibitor with a Dbait molecule for treating cancer.Type: GrantFiled: February 14, 2020Date of Patent: November 2, 2021Assignees: INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ONXEO, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, UNIVERSITE PARIS-SUD 11Inventors: Marie Dutreix, Wael Jdey
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Patent number: 10563197Abstract: The present invention relates to the combination of a PARP inhibitor with a Dbait molecule for treating cancer.Type: GrantFiled: July 22, 2016Date of Patent: February 18, 2020Assignees: INSTITUT CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ONXEO, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE, UNIVERSITE PARIS-SUD 11Inventors: Marie Dutreix, Wael Jdey
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Publication number: 20190367608Abstract: The present invention relates to an isolated humanized protein binding to human Glycoprotein VI (hGPVI) for treating a GPVI-related condition in a subject in need thereof, wherein said isolated humanized protein is to be administered during at least 2 hours to the subject, preferably during at least 4 to 6 hours.Type: ApplicationFiled: February 2, 2018Publication date: December 5, 2019Applicants: Acticor Biotech, Université Paris Diderot - Paris 7, Université Paris-XIII, Nserm (Institut National de la Santé et de la Recherche Médicale), Université Paris-Sud 11Inventors: Philippe BILLIALD, Martine JANDROT-PERRUS, Gilles AVENARD
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Patent number: 10438128Abstract: The invention concerns the field of human auto-immune and/or inflammatory diseases, and more specifically the use of arsenic compounds for the preparation of drugs intended for the treatment and/or prevention of skin injuries associated with auto-immune and/or inflammatory diseases in a human subject. The invention concerns an arsenic compound As2O5 for use in the treatment and/or prevention of skin injuries associated with auto-immune and/or inflammatory diseases in a human subject, a pharmaceutical composition comprising an arsenic compound As2O5, preferably for the treatment and/or prevention of skin injuries associated with auto-immune diseases in a human subject, and products containing an arsenic compound As2O5 and an arsenic compound As2O3 as a combination product for simultaneous, separated or time-spread use in the treatment and/or prevention of skin injuries associated with auto-immune diseases in a human subject.Type: GrantFiled: April 25, 2014Date of Patent: October 8, 2019Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE PARIS-SUD 11Inventors: Mohcine Benbijja, Pedro Bobe
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Patent number: 10317656Abstract: An optical tomography apparatus comprises: a polychromatic light source, a one-dimensional optical sensor, an interferometric microscope, a one-dimensional confocal spatial filtering system, an actuation system making it possible to perform a one-way scan depthwise of an object to be observed and a processor for reconstructing a two-dimensional image of a section of the object from a plurality of one-dimensional interferential images acquired by the image sensor during the one-way scan. An optical tomography method based on use of such an apparatus is also provided.Type: GrantFiled: December 19, 2014Date of Patent: June 11, 2019Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, Institut d'Optique Graduate School, UNIVERSITE PARIS SUD 11Inventor: Arnaud Dubois
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Patent number: 10272157Abstract: A process for preparing a porous solid with an outer surface modified by at least one polymer; the polymer being simultaneously synthetized in solution and grafted on the outer surface of the solid, includes contacting: a porous solid; and a polymer-precursor solution comprising an adhesion primer, and at least one polymerizable monomer; under conditions enabling the formation of radical entities.Type: GrantFiled: October 8, 2015Date of Patent: April 30, 2019Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (CEA), CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE VERSAILLES SAINT-QUENTIN-EN-YVELINES, UNIVERSITE PARIS-SUD 11Inventors: Thomas Berthelot, Elena Bellido Vera, Ruxandra Gref, Patricia Horcajada Cortes, Christian Serre, Patrick Couvreur
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Patent number: 10172947Abstract: A composition including hydrophobized chitosan can be used as an antiparasitic and/or antifungal agent or in the treatment of parasitic and/or fungal infections. The composition may include an antifungal agent and hydrophobized chitosan. The antifungal agent can be in association with the hydrophobized chitosan, with the latter being more preferably in the particle form, or the antifungal agent can be encapsulated in particles including the hydrophobized chitosan. The use of the composition as an antifungal agent or in the treatment of fungal infections, and a method for manufacturing the composition are also described.Type: GrantFiled: October 9, 2014Date of Patent: January 8, 2019Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIFQUE (CNRS), UNIVERSITE PARIS-SUD 11Inventors: Kawthar Bouchemal, Christian Bories, Philippe Loiseau, Christine Vauthier-Holtzscherer, Sebastien Pomel, Benedicte Pradines
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Patent number: 10157726Abstract: The invention relates to a cathodoluminescence detection system comprising: a collecting optic (112) collecting light radiation (108) from a sample illuminated by a beam of charged particles and reflecting said radiation (108) onto analysis means, said collecting optic (112) being placed in a chamber, called a vacuum chamber, wherein the pressure is below atmospheric pressure; and means (316) for adapting the light radiation, placed downstream of the collecting optic (112) and designed to adapt said light radiation (108) at the inlet of the analysis means. Said system is characterized in that all or part of the adapting means (316) is placed in an environment where the pressure is higher than the pressure in said vacuum chamber.Type: GrantFiled: April 29, 2011Date of Patent: December 18, 2018Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS SUD 11Inventors: Mathieu Kociak, Luiz Fernando Zagonel, Marcel Tence, Stefano Mazzucco
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Patent number: 10071080Abstract: The present invention relates to the use of compounds of general Formula I and pharmaceutically acceptable enantiomers, salts or solvates thereof, for treating pulmonary hypertension in a subject.Type: GrantFiled: May 18, 2015Date of Patent: September 11, 2018Assignees: MIFCARE, INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITÉ PARIS-SUD 11Inventors: Gaël Jalce, Christophe Guignabert, Morane Le Hiress, Ly Tu, Bernardin Akagah
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Patent number: 9791439Abstract: A component or device is provided for the detection or the measurement in parallel of one or more specific types of biological or chemical target products. This component includes a group of nanotubes selected and/or functionalized to interact with the target product, around an optical waveguide. Thus, an optical coupling is produced between the optical waveguide and one or more optical characteristics of these nanotubes, the modifications of which are evaluated in the presence of the target product. In addition, a method is provided for manufacturing and preparing such a component or device, and a detection method using them, as well as a post-manufacture preparation method comprising a specific functionalization for different target products starting from the same type of pluripotent generic component. Also provided is a family of PFO-based functionalization polymers.Type: GrantFiled: February 9, 2012Date of Patent: October 17, 2017Assignees: UNIVERSITE PARIS SUD 11, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Laurent Vivien, Etienne Gaufres, Nicolas Izard, Eric Doris, Edmond Gravel, Didier Boquet
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Patent number: 9709501Abstract: The present invention relates to an in vitro method for diagnosing the infectious state of an individual on the basis of a sample of white corpuscles arising from a biological specimen taken from an organ potentially infected by a pathogenic microorganism of said individual, comprising at least the following two steps: i) measuring the mean cellular intensity of the autofluorescence of said sample, and ii) comparing the intensity measured in step i) with a control value, so as to determine the infectious state of said individual. The diagnostic method of the invention uses a routine optical material making it possible to work in wavelength regions which are compatible with the cellular autofluorescence, and thus constitutes a rapid, reliable and inexpensive aid for the diagnosis or monitoring of an infection in an individual.Type: GrantFiled: March 22, 2012Date of Patent: July 18, 2017Assignees: UNIVERSITE DE NANTES, UNIVERSITE PARIS-SUD 11, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)Inventors: Karim Asehnoune, Marie-Pierre Fontaine-Aupart, Sandrine Lecart, Antoine Monsel, Antoine Roquilly
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Patent number: 9616010Abstract: The invention relates to a ternary lipid association of ?-sitosterol, isocetyl stearoyl stearate and glyceryl tri-2-ethylhexanoate, wherein the ?-sitosterol content of said association is between 0.1% and 5 wt. %.Type: GrantFiled: July 11, 2014Date of Patent: April 11, 2017Assignees: PIERRE FABRE DERMO-COSMETIQUE, UNIVERSITE PARIS-SUD 11, CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSEInventors: Hélène Duplan, Daniel Redoules, Alexandre Delalleau
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Patent number: 9606113Abstract: The present invention relates to a method for diagnosing a neurodegenerative disease in a subject, wherein the level of each of at least two catecholamines is measured in a sample of biological fluid from said subject.Type: GrantFiled: September 17, 2012Date of Patent: March 28, 2017Assignees: Centre National De La Recherche Scientifique (C.N.R.S), Universite Paris-Sud 11Inventors: Myriam Taverna, Romain Verpillot, Markus Otto, Hans Klafki
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Patent number: 9568671Abstract: A photonic component is provided including at least one linear optical waveguide, of which an active portion is surrounded over all or part of its periphery by a grouping of one or more essentially semiconducting nanotubes. These nanotubes interact with their exterior environment in an active zone extending on either side of the optical waveguide, to thus induce an optical coupling between an electrical or optical signal applied to the nanotubes and on the other hand an optical signal in the active portion of the waveguide. Such a component can carry out bipolar electro-optical functions as light source, or modulator or detector, inside the optical guide, for example with an electro-optical coupling between on the one hand an electrical signal applied between the electrodes, and on the other hand an optical signal emitted or modified in the active portion of the optical waveguide towards the remainder of the optical guide.Type: GrantFiled: June 15, 2011Date of Patent: February 14, 2017Assignees: UNIVERSITE PARIS SUD 11, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Laurent Vivien, Etienne Gaufres, Nicolas Izard
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Patent number: 9461586Abstract: An oscillator is provided including a nanopillar and current injector for injecting a power supply current through the nanopillar, the nanopillar including at least one pattern including first and second layers made from a ferromagnetic material separated from each other by an intermediate layer made from a non-magnetic material. Each of the first and second ferromagnetic layers is prepared such that its remanent magnetic configuration corresponds to a vortex configuration and the polarity of the vortex core of the first layer is opposite the polarity of the vortex core of the second layer. The intermediate layer can allow repellant magnetic coupling between the two vortices of the first and second layers, for a zero intensity of the power supply current and a zero amplitude of the outside magnetic field.Type: GrantFiled: July 12, 2012Date of Patent: October 4, 2016Assignees: THALES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE PARIS-SUD 11Inventors: Nicolas Locatelli, Bruno Marcilhac, Jean-Claude Mage, Vincent Cros, Alexey Vasilyevich Khvalkovskiy, Julie Grollier
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Publication number: 20160243243Abstract: A composition including hydrophobised chitosan can be used as an antiparasitic and/or antifungal agent or in the treatment of parasitic and/or fungal infections. The composition may include an antifungal agent and hydrophobised chitosan. The antifungal agent can be in association with the hydrophobised chitosan, with the latter being more preferably in the particle form, or the antifungal agent can be encapsulated in particles including the hydrophobised chitosan. The use of the composition as an antifungal agent or in the treatment of fungal infections, and a method for manufacturing the composition are also described.Type: ApplicationFiled: October 9, 2014Publication date: August 25, 2016Applicants: Centre National de la Recherche Scientifique (CNRS), Universite Paris-Sud 11Inventors: Kawthar BOUCHEMAL, Christian BORIES, Philippe LOISEAU, Christine VAUTHIER-HOLTZSCHERER, Sebastien POMEL, Benedicte PRADINES
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Publication number: 20160166490Abstract: The invention relates to a ternary lipid association of ?-sitosterol, isocetyl stearoyl stearate and glyceryl tri-2-ethylhexanoate, wherein the ?-sitosterol content of said association is between 0.1% and 5 wt. %.Type: ApplicationFiled: July 11, 2014Publication date: June 16, 2016Applicants: PIERRE FABRE DERMO-COSMETIQUE, UNIVERSITE PARIS-SUD 11, CENTRE HOSPITALIER UNIVERSITAIRE DE TOULOUSEInventors: Hélène DUPLAN, Daniel REDDULES, Alexandre DELALLEAU
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Patent number: 9327961Abstract: The present invention relates to the field of electrodynamic speakers. Particularly, the present invention relates to an electrodynamic speaker structure having MEMS technology. More particularly, the invention relates to such a structure comprising stator-forming means, diaphragm-forming means, and resiliently shape-changing means for connecting such means.Type: GrantFiled: January 14, 2011Date of Patent: May 3, 2016Assignees: UNIVERSITE DU MAINE, UNIVERSITE PARIS-SUD 11Inventors: Guy Lemarquand, Valerie Lemarquand, Elie Marie Lefeuvre, Marion Alexandra Laurence Woytasik, Johan Moulin, Fabien Jean François Parrain
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Patent number: 9320804Abstract: The present invention relates to a polymer obtained from the polymerization of: (i) at least one monomer of formula (I) (CH2?CR1)CO—K (I) wherein: K represents 0-Z or NH—Z, Z representing (CR2R3)m—CH3, (CH2—CH2—O)m—H, (CH2—CH2—O)m—CH3, (CH2)m—NR4R5 with m representing an integer from 1 to 30; R1, R2, R3, R4 and R5 independently represent H or a C1-C6 alkyl; and (ii) at least one bio-resorbable block copolymer cross-linker.Type: GrantFiled: September 9, 2010Date of Patent: April 26, 2016Assignees: OCCLUGEL, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), UNIVERSITE PARIS-SUD 11, ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS, UNIVERSITE PARIS DIDEROT PARIS 7Inventors: Laurence Moine, Laurent Bedouet, Alexandre Laurent, Denis Labarre, Michel Wassef, Van Nga Nguyen