Abstract: The invention relates to a Microbulbifer bacterial strain isolated from a marine sponge, to its use in a process for manufacturing paraben compounds. The invention also relates to paraben compounds obtained from that Microbulbifer strain and to their uses. The Microbulbifer strain of the invention is Microbulbifer strain named L4-N2 deposited at the CNCM under the registration number 1-3714. The process of manufacturing paraben compounds of the invention makes use of this Microbulbifer strain. The invention finds application in the manufacture of paraben compounds, for use in particular in cosmetic, pharmaceutical, antifouling, detergent, sanitizing and disinfectant compositions.

Abstract: The invention pertains to methods for using chimeric polypeptides of the formula: B-X wherein B represents the B fragment of Shiga toxin or a functional equivalent thereof, and X represents one or more polypeptides of therapeutic significance. Compositions for therapeutic use comprising the polypeptide B-X are also included.

Abstract: The invention relates to a fluorescent emulsion, to a diagnostic reagent containing the same, and to the use thereof in the preparation of a diagnostic reagent for in vivo fluorescence imaging.

Abstract: The present invention relates to a method of vaccination via hair follicles that makes it possible to target vaccine components to the antigen-presenting cells in order to induce a protective and effective immune response against pathogens.

Abstract: The invention provides a method of fastening lamellae of a lamellar material that is at least partially conductive onto an insulating substrate (2) containing oxides that are suitable for dissociating into mobile ions of given charge and stationary ions of opposite charge, the method comprising the steps of: placing a sample (1) of the lamellar material against a surface of the substrate; causing the oxides of the substrate to dissociate; and subjecting the substrate and the sample to an electric field by means of an electrode in contact with the substrate and an electrode in contact with the sample.

Abstract: The invention relates to the use of allogenic T lymphocytes for the preparation of a composition intended to be injected into a recipient patient as a conditioning for a transplantation of haematopoietic stem cells, said allogenic T lymphocytes expressing a molecule allowing their specific destruction.

Abstract: The invention relates to the treatment of a tumor in a patient, by injecting T lymphocytes depleted of regulatory T lymphocytes, and expressing a molecule allowing their specific destruction, the patient receiving beforehand a non-myeloablative or myeloablative lymphopenic treatment.

Abstract: The invention relates to the use of at least one globin and/or at least one globin protomer and/or at least one naturally extracellular native hemoglobin for the preservation of organs, tissues, organ and tissue cells and cell cultures.

Abstract: The invention relates to pyrrolo[2,3-b]pyridine compounds and azaindole compounds used for the synthesis thereof. The invention also relates to methods for the production thereof and the uses thereof. Said novel pyrrolo[2,3-b]pyridine compounds according to the invention have great antiproliferative, apoptotic, and neuroprotective activities. The invention particularly applies to the pharmaceutical field.

Abstract: The present invention relates to methods for identifying novel PP1-interacting polypeptides and proteins, compounds which are able to inhibit the binding of PP1c to certain factors naturally interacting with it, especially proteins of the Bcl-2 family (such as BCl-xL and Bcl-w), and pharmaceutical compositions comprising the same.

Abstract: A support designed for observing between intersecting polarizers an object located in its vicinity in a medium (3) of index n0 with incident convergent incoherent illumination under an angle ?0 at a wavelength ?. The support includes a substrate (1) with complex refractive index n2 and a layer (2) of refractive index n1 and thickness e1. The value of the thickness e1 of the layer (2) is at ±2% such that d2?/de21 lnIóI2=0 with Ó=Ó01+Ó12 (1+?01)e(?2j?1)+Ó01 ?12e (?4j?1)/1+r01(p)+r12(p)e(?2j?1))(1+r01(s)r12(s)e(?2j?1)). Observation devices incorporating such a support are also disclosed.

Abstract: The present invention relates to a spacecraft (P) comprising a propulsion system (1) making it possible to exert a force of variable magnitude and orientation on the spacecraft, a control system designed to control the propulsion system in terms of magnitude and orientation so as to make the spacecraft approach a target around a planet, with the aid of a force which comprises at least one component (fx, fy, fz), in the rotating reference frame tied to the target, which depends substantially linearly on the corresponding coordinate (x, y, z) of the craft in this reference frame.

Abstract: The present invention relates to a hydraulic system that includes a compression chamber capable of being subjected to the pressure of a hydraulic fluid; a piston movable inside the compression chamber along an axis; and at least one sealing gasket disposed between the piston and a wall of the compression chamber, the gasket occupying an axial position that varies circumferentially around the axis in such a manner as to compensate for non-axially symmetrical stresses induced by the pressure of the fluid.