Abstract: The invention relates to a device for viewing a digital image comprising means (2) for viewing at least one portion of the digital image. According to the invention, the viewing means include a viewing mask (2) held by a stand (3) such that the viewing mask (2) is used at the eye level of a user such that same can bring his/her eyes closer to the viewing mask in order to examine the portion of the digital image displayed, the viewing mask comprising side extensions (6g, 6d) for protecting the user from outer visual interferences, and in that the viewing device further includes at least one movement handling device (7, 200) that can be controlled by the user in order to control virtual movement of the digital image such that the user is able to view another portion of the digital image.

Abstract: The invention relates to an assistive device for positioning a medical instrument (2) inserted into a natural duct (100) or an artificial duct of a patient relative to an internal organ (P) of a patient, wherein the device comprises a support (1) that is to be inserted at least in part into the body of the patient and supports the medical instrument, means for moving the support, wherein said movement means comprise an articulated arm (9) that includes a plurality of degrees of freedom for moving a proximal end (1a) of the support, means for acquiring images of the internal organ for positioning the medical instrument relative to the internal organ, wherein the image acquisition means comprise a probe (5) supported by the support such that the medical instrument and the probe are rigidly connected, and a control unit (10) for controlling the movement means, which is connected to the image acquisition means and comprises image analyzing means (11) for generating control commands for the articulated arm in orde

Abstract: The invention relates to a miniature linear vibrotactile actuator comprising: a first element 14, 104 of generally cylindrical shape, comprising permanent magnets 15, 105 aligned so that two adjacent sides of two adjacent magnets 15, 105 have identical polarities; a second element 11, 101 defining a cylindrical cavity 12, 102 into which the first element 14, 104 is inserted with play so as to be able to slide therein in a sliding direction X2, the second element 11, 101 comprising coils 13, 103 of conductive wire having strands that extend perpendicularly to the sliding direction X2, in order to form magnetic force generators, and that are placed so as to be able to influence the first element 14, 104 electromagnetically; and means 25, 41, 125 for returning and guiding the first element 14, 104 toward an equilibrium position in the second element 11, 101, in which position a median plane P2 between two adjacent magnets substantially coincides with a median plane P1 of a facing force generator 111.

Abstract: A method of 3D reconstruction of a scene, including the implementation of at least two sensors each having a series of elementary receivers arranged so as to view the scene according to distinct respective solid angles and which are each sensitive to a physical characteristic of a signal received by the receiver originating from the scene. The sensors are adapted for emitting an asynchronous stream of events indicative of a modification of the signal received by one of the elementary receivers at a given instant, as well as the implementation of a 3D reconstruction algorithm having a step of pairing elementary receivers of each of the sensors utilizing signals generated by the sensors, the pairing including pairing between them events generated by each of the sensors and temporarily close together.

Abstract: A multipurpose computing device includes a solver receiving a working matrix and an initial matrix corresponding to a system of equations and residual data; and an adapter receiving the initial matrix as well as a filtering matrix and calculates a working matrix corresponding to an equation system solved by the solver. The working matrix checks a stability condition with the initial matrix, comprising a comparison of two matrix products including the filtering matrix or the transpose thereof, and the initial matrix and the working matrix, respectively. The adapter renumbers the initial matrix and the filtering matrix in order to produce a modified matrix and a modified filtering matrix using an ordering rule that is a function of a dependency condition, and recursively calculates the working matrix representation with these matrices. The solver works recursively on the working matrix to provide a solution without inverting the initial matrix.

Abstract: The present invention describes the use of nucleoside analogues for the treatment of viral infections, in particular of an HIV infection, and also compositions comprising at least one of these analogues, and a method for evaluating the sensitivity to said treatment.

Abstract: The present invention relates to a method for producing polyphenol compounds, i.e. phloroglucinol or one of its derivatives, with a polyketide synthase of type III (PKSIII) from a brown marine alga. The invention also relates to recombinant nucleic acids coding for a polyketide synthase of type III (PKSIII) from the brown alga Ectocarpus siliculosus (E. siliculosus), to recombinant vectors comprising these nucleic acids, as well as to host cells comprising these vectors. Finally, the invention relates to a method for preparing of various compounds by means of polyphenol compounds produced according to the aforementioned method.

Abstract: A method is provided for storing hydrogen in a macroporous monolithic material by the heterogeneous nucleation of a metal hydride. A composite material is provided for storing hydrogen directly obtained by the method. A method is also provided for employing the material for the production of dihydrogen, as well as a method for producing dihydrogen using such a composite material.

Abstract: The present disclosure relates to iminosugar derivatives and processes for the preparation thereof. The disclosed compounds have glycosidase inhibiting properties, and are useful in the treatment of various diseases, such as type 2 diabetes, neurodegenerative diseases or lysosomal storage disorders. The present disclosure also relates to pharmaceutical compositions containing the disclosed compounds and to their use as biochemical tools.

Abstract: The invention relates to a device for guiding a medical instrument (2) inserted into a natural duel (101) or an artificial duct of a patient in order to bring at least a distal end (1) of the instrument in proximity to an internal organ (100), the device comprising an articulated arm (3) with a plurality of degrees of freedom, for moving a proximal end (4) of the instrument, and controlled blocking means (7) for blocking the degrees of freedom of the articulated arm. According to the invention, the blocking means are designed in such a way that, for at Mast one of the degrees of freedom, a blockage imposed on said degree of freedom can be enforced when an outer stress exerted on the instrument (2) exceeds a predetermined threshold.

Abstract: A method for employing certain cobalt complexes as electron donors and in combination with an electron acceptor is provided for preparing an active layer in a photovoltaic conversion cell, as well as to the photovoltaic conversion cell in which the electron donor of the active layer includes such cobalt complexes.

Abstract: The invention relates to a surgical instrument (100; 200) comprising: an elongated arm (111; 207) according to a longitudinal axis and having a distal end (105; 204) mounted with a pivot joint on the elongated arm according to an axis substantially orthogonal to the longitudinal axis; a drive shaft (103; 3), substantially coaxial with the elongated arm, comprising means forming a universal joint (104; 206) facing the pivot joint; and, distal tool (9) securely fastened on the drive shaft and rotatively mounted on and in the extension of the distal end of the elongated arm, such that the distal tool has two rotational degrees of freedom, distinct and independent of each other, one being around an axis substantially perpendicular to the longitudinal axis of the elongated arm and the other being around an axis substantially collinear to an own axis of the distal tool, characterized in that the means forming a universal joint comprise a flexible drive sleeve (104; 206).

Abstract: The invention relates to the use of at least one globin and/or at least one globin protomer and/or at least one naturally extracellular native hemoglobin for the preservation of organs, tissues, organ and tissue cells and cell cultures.

Abstract: A system (1) for treating at least one sensory capacity of a person with the help of a stimulation device comprising: an electronic converter (7) of a sensory signal into an electronic signal for controlling at least one transducer for emitting signals that are images of the sensory signal; the stimulation device is a device (3) for direct ultrasound stimulation of the sensory cortex of the patient's brain (B), comprising: at least one support (2) that is implantable in the patient's skull (C) and that includes at least one internal wall (22); and at least one ultrasound transducer (4) carried by the support (2) and including means for emitting focused ultrasound waves (U) through the internal wall (22) of the support towards a determined zone of the sensory cortex of the patient's brain (B) in order to generate modulation of the brain activity in the cortex, the ultrasound transducer (4) being driven by the electronic converter to emit focused ultrasound signals (U) that are images of the sensory signal.

Abstract: The invention relates to a system comprising an oculometer for measuring movements of at least one eye of an operator, wherein it comprises furthermore a display for displaying, for the eye, a frame of at least one point performing a blinking, so that the operator can perform at least one smooth tracking movement of the eye while looking at the display while operating. The invention also relates to a method implemented on such a system, and a corresponding computer program product.

Abstract: The invention relates to a method for determining a predictive function for discriminating patients according to their disease activity status, comprising steps of: a—measuring values of biological markers for each patient of a first group of patients having a first known disease activity status, and for each patient of a second group of patients having a second known disease activity status, the measured values forming a dataset b—analyzing the dataset for identifying biological markers which are differentially expressed between the first group of patients and the second group of patients, c—among the biological markers identified at step b, determining correlated markers as markers which are correlated with other markers above a predetermined significance level, d—removing from the dataset, values measured for a biological marker identified as correlated marker, e—analyzing the dataset obtained at step d for determining a predictive function that predicts a disease activity status of a patient as a combinat

Abstract: The invention relates to peptides for modulate IGF-1 activity, a pharmaceutical composition comprising them as well as their applications as medicinal products and cell proliferation modulating agents in vitro.

Abstract: A device, having first and second motor units, for generating a torque on an output member in response to a torque setpoint. The first motor unit includes at least one motor of a first power, or small motor, having a shaft to which the output member is connected. The second motor unit includes at least one motor of a second power higher than the first power, or large motor, having a shaft rotationally connected to the output member via viscous coupler, and computer programmed, in response to a torque setpoint, to power the second motor unit so that the viscous coupler provides a viscous torque conforming to the torque setpoint. Further, in parallel with this, the first motor unit is powered so that it produces the additional torque between the torque setpoint and the viscous torque until the viscous torque reaches the value of the torque setpoint.

Abstract: A method for reading an emulsion (3) including droplets and a continuous phase surrounding the droplets, the method includes: two-dimensional scanning of the emulsion (3), and construction of a two-dimensional image of the emulsion (3) based on the scanning. Preferably, the droplets do not move during scanning, for example by solidifying the continuous phase or by using a two-dimensional compact or semi-compact network of droplets. The method can further include time-based monitoring of a chemical or biological reaction taking place in at least one of the droplets. A device implementing this method is also described. The method is applicable for the detection and/or sorting of microdroplets performing the role of microreactors or containing specific cells or molecules, in fields such as gene expression or diagnosis.

Abstract: The present invention concerns iodoperoxidases from Zobellia galactanivorans, isolated nucleic acids encoding same, as well as methods for preparing these enzymes. Moreover, the invention is also directed to the use of such iodoperoxidases in a wide range of industrial, pharmaceutical, medical, cosmetics, and ecological applications, as well as in the food industry.