Patents Assigned to Universités Paris 6 et Paris 7
  • Leptin antagonists
    Patent number: 7307142
    Abstract: The invention relates to synthetic leptin antagonists in which at least two amino acid residues of the sequence LDFI/S of the hydrophobic binding site at positions 39-42 of a leptin polypeptide sequence are substituted with different amino acid residues such that the site becomes less hydrophobic, and fragments of said leptin antagonists.
    Type: Grant
    Filed: November 26, 2004
    Date of Patent: December 11, 2007
    Assignees: Yissum Research and Development Company of the Hebrew University of Jerusalem, Universités Paris 6 et Paris 7, Institut Nationale de la Recherche Agronomique (INRA)
    Inventors: Arieh Gertler, Isabelle Callebaut, Jean Djiane
  • Leptin antagonists
    Publication number: 20060154859
    Abstract: The invention relates to synthetic leptin antagonists in which at least two amino acid residues of the sequence LDFI/S of the hydrophobic binding site at positions 39-42 of a leptin polypeptide sequence are substituted with different amino acid residues such that the site becomes less hydrophobic, and fragments of said leptin antagonists.
    Type: Application
    Filed: November 26, 2004
    Publication date: July 13, 2006
    Applicants: Yissum Research Development Company of The Hebrew University of Jerusalem, Universites Paris 6 et Paris 7, Institut Nationale de la Recherche Agronomique (INRA)
    Inventors: Arieh Gertler, Isabelle Callebaut, Jean Djiane