Patents Assigned to UNIVERSITÄT AUTONOMA DE BARCELONA
  • Telomerase reverse transcriptase-based therapies for treatment of conditions associated with myocardial infarction
    Patent number: 11261434
    Abstract: The invention provides compositions and methods useful for the treatment and prevention of conditions associated with myocardial infarction.
    Type: Grant
    Filed: August 4, 2015
    Date of Patent: March 1, 2022
    Assignees: Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO), Universität Autónoma de Barcelona
    Inventors: Maria Antonia Blasco Marhuenda, Bruno Bernardes De Jesus, Christian Baer, Rosa María Serrano Ruiz, Fàtima Bosch I Tubert, Eduard Ayuso, Ivan Formentini, Maria Bobadilla, Jacques Mizrahi
  • Single-vector gene construct comprising insulin and glucokinase genes
    Patent number: 11033638
    Abstract: The invention relates to a viral expression construct and related viral vector and composition and to their use wherein the construct and vector comprise elements a) and b): a) a nucleotide sequence encoding an insulin operably linked to a first promoter, b) a nucleotide sequence encoding a glucokinase operably linked to a second promoter and the viral expression construct and related viral vector comprise at least one of elements c), d) and e): c) the first and the second promoters are positioned in reverse orientation within the expression construct, d) the first and the second promoters are positioned in reverse orientation within the expression construct and are located adjacent to each other and e) the first promoter is a CMV promoter, preferably a mini CMV promoter.
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: June 15, 2021
    Assignee: UNIVERSITÄT AUTONOMA DE BARCELONA
    Inventors: Fatima Bosch Tubert, Miguel Garcia Martinez, Veronica Jiménez Cenzano, Virginia Haurigot Mendonça