Patents Assigned to Universität Greifswald
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Patent number: 10744095Abstract: The present invention relates to a pharmaceutical dosage form for application to a mucous membrane, in particular to a buccal, intestinal, rectal or vaginal mucous membrane, comprising at least one sheet like, in particular film shaped, foil shaped or wafer shaped preparation comprising the active pharmaceutical ingredient, a release mechanism, and a trigger mechanism, wherein the trigger mechanism is adapted to trigger, at a predetermined site of action, in particular of the gastrointestinal tract, of the rectum or of the vagina, the release of the sheet like preparation by the release mechanism.Type: GrantFiled: December 22, 2015Date of Patent: August 18, 2020Assignee: Universität GreifswaldInventors: Malte Bogdahn, Kirsten Kirsch, Michael Grimm, Mirko Koziolek, Werner Weitschies
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Patent number: 9963741Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.Type: GrantFiled: April 3, 2015Date of Patent: May 8, 2018Assignees: ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD, DRK BLUTSPENDEDIENST WEST GMBHInventors: Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
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Patent number: 9150515Abstract: The present invention relates to imidazolium salts, particularly imidazolium salts of the general formula I as well as the respective carbene metal complexes and their utilization as bioanalytical tags for biomolecules.Type: GrantFiled: September 5, 2011Date of Patent: October 6, 2015Assignee: ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALDInventor: Olaf Kuehl
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Patent number: 8999651Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.Type: GrantFiled: March 18, 2013Date of Patent: April 7, 2015Assignees: Ernst-Moritz-Arndt-Universität Greifswald, DRK Blutspendedienst West GmbHInventors: Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
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Patent number: 8435733Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.Type: GrantFiled: November 29, 2011Date of Patent: May 7, 2013Assignees: Ernst-Moritz-Arndt-Universität Greifswald, DRK Blutspendedienst West GmbHInventors: Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
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Patent number: 8257729Abstract: An implant for implantation in a human or animal body having a structure comprising a) an implant base body; b) a primer layer which is partially or completely applied to the surface of the implant; c) an active ingredient layer consisting of one, two, three or more active ingredients applied entirely or partially to the surface of the primer layer; and d) a diffusion-controlling layer which is applied partially or entirely to the active ingredient layer, and optionally to the primer layer, wherein diffusion of the active ingredients of the active ingredient layer is controlled. Also disclosed is a manufacturing method for an implant.Type: GrantFiled: December 10, 2008Date of Patent: September 4, 2012Assignees: Biotronik VI Patent AG, Universitaet Rostock, Universitaet GreifswaldInventors: Klaus-Peter Schmitz, Detlef Behrend, Katrin Sternberg, Niels Grabow, Claus Harder, Bjoern Klocke, Heyo K. Kroemer, Werner Weitschies
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Publication number: 20120070834Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.Type: ApplicationFiled: November 29, 2011Publication date: March 22, 2012Applicants: DRK BLUTSPENDIENST WEST GMBH, ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALDInventors: ANDREAS GREINACHER, JAN WESCHE, JUERGEN BUX, ANGELIKA REIL
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Patent number: 8084216Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.Type: GrantFiled: September 3, 2009Date of Patent: December 27, 2011Assignees: Ernst-Moritz-Arndt-Universität Greifswald, DRK Blutspendedienst West GmbHInventors: Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
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Publication number: 20110159273Abstract: The invention relates to a method for coating surfaces with micro- and nanoparticles, the micro- and nanoparticles being chemically bonded to the surface, comprising the steps of pre-treatment of the surface with a plasma method, simultaneous or subsequent application of the micro- and nanoparticles to the surface, and subsequent fixation of the micro and nanoparticles on the surface using a plasma method, characterized in that the fixation of the micro- and nanoparticles takes place with the aid of anisothermal plasmas, the median electrical energy of which lies in the range of the bond dissociation energy of the micro- and nanoparticles, thus allowing the strength of the chemical bond between the surface and the micro- and nanoparticles to be variably set.Type: ApplicationFiled: May 31, 2008Publication date: June 30, 2011Applicants: Ernst-Moritz-Arndt-Universitaet Greifswald, Inst Fuer Niedertemp.-Plasmaphysik E.V. GreifswaldInventors: Gerold Lukowski, Karsten Schroeder, Wolf-Dieter Juelich, Ruediger Foest, Klaus-Dieter Weltmann, Joerg Ehlbeck
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Patent number: 6517786Abstract: A decomposition device and a method for decomposing gases with soot or other harmful substances has a processing station using dielectrically hindered discharge. The device has at least two electrodes, one of which is a porous and gas permeable electrode. In order to decompose the gas containing harmful substances, the gas is first introduced into a processing station in which the gas is subjected to plasma processing involving an alternate voltage supply, and from which the gas is let out. The gas is introduced through one end of the processing station formed by the two electrodes.Type: GrantFiled: January 10, 2000Date of Patent: February 11, 2003Assignee: Institute fuer Niedertemperatur-Plasmaphysik E. V. An der Ernst-Moritz-Arndt-Universitaet GreifswaldInventors: Walter Best, Johannes Peter Franziskus Conrads, Wolf-Dieter Franke, Siegfried Mueller, Wolfgang Reich