Patents Assigned to Universität Greifswald
  • Patent number: 10744095
    Abstract: The present invention relates to a pharmaceutical dosage form for application to a mucous membrane, in particular to a buccal, intestinal, rectal or vaginal mucous membrane, comprising at least one sheet like, in particular film shaped, foil shaped or wafer shaped preparation comprising the active pharmaceutical ingredient, a release mechanism, and a trigger mechanism, wherein the trigger mechanism is adapted to trigger, at a predetermined site of action, in particular of the gastrointestinal tract, of the rectum or of the vagina, the release of the sheet like preparation by the release mechanism.
    Type: Grant
    Filed: December 22, 2015
    Date of Patent: August 18, 2020
    Assignee: Universität Greifswald
    Inventors: Malte Bogdahn, Kirsten Kirsch, Michael Grimm, Mirko Koziolek, Werner Weitschies
  • Patent number: 9963741
    Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: May 8, 2018
    Assignees: ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD, DRK BLUTSPENDEDIENST WEST GMBH
    Inventors: Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
  • Patent number: 9150515
    Abstract: The present invention relates to imidazolium salts, particularly imidazolium salts of the general formula I as well as the respective carbene metal complexes and their utilization as bioanalytical tags for biomolecules.
    Type: Grant
    Filed: September 5, 2011
    Date of Patent: October 6, 2015
    Assignee: ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD
    Inventor: Olaf Kuehl
  • Patent number: 8999651
    Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.
    Type: Grant
    Filed: March 18, 2013
    Date of Patent: April 7, 2015
    Assignees: Ernst-Moritz-Arndt-Universität Greifswald, DRK Blutspendedienst West GmbH
    Inventors: Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
  • Patent number: 8435733
    Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.
    Type: Grant
    Filed: November 29, 2011
    Date of Patent: May 7, 2013
    Assignees: Ernst-Moritz-Arndt-Universität Greifswald, DRK Blutspendedienst West GmbH
    Inventors: Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
  • Patent number: 8257729
    Abstract: An implant for implantation in a human or animal body having a structure comprising a) an implant base body; b) a primer layer which is partially or completely applied to the surface of the implant; c) an active ingredient layer consisting of one, two, three or more active ingredients applied entirely or partially to the surface of the primer layer; and d) a diffusion-controlling layer which is applied partially or entirely to the active ingredient layer, and optionally to the primer layer, wherein diffusion of the active ingredients of the active ingredient layer is controlled. Also disclosed is a manufacturing method for an implant.
    Type: Grant
    Filed: December 10, 2008
    Date of Patent: September 4, 2012
    Assignees: Biotronik VI Patent AG, Universitaet Rostock, Universitaet Greifswald
    Inventors: Klaus-Peter Schmitz, Detlef Behrend, Katrin Sternberg, Niels Grabow, Claus Harder, Bjoern Klocke, Heyo K. Kroemer, Werner Weitschies
  • Publication number: 20120070834
    Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.
    Type: Application
    Filed: November 29, 2011
    Publication date: March 22, 2012
    Applicants: DRK BLUTSPENDIENST WEST GMBH, ERNST-MORITZ-ARNDT-UNIVERSITÄT GREIFSWALD
    Inventors: ANDREAS GREINACHER, JAN WESCHE, JUERGEN BUX, ANGELIKA REIL
  • Patent number: 8084216
    Abstract: The invention relates to the discovery that HNA-3a and HNA-3b are antigens within a polypeptide sequence that is highly similar to the CTL2 amino acid sequence. This invention provides methods and kits for screening for HNA-3a and HNA-3b specific antibodies, HNA-3a and HNA-3b polypeptides and HNA-3a and HNA-3b nucleic acids in a sample of a biological tissue intended for transplantation.
    Type: Grant
    Filed: September 3, 2009
    Date of Patent: December 27, 2011
    Assignees: Ernst-Moritz-Arndt-Universität Greifswald, DRK Blutspendedienst West GmbH
    Inventors: Andreas Greinacher, Jan Wesche, Juergen Bux, Angelika Reil
  • Publication number: 20110159273
    Abstract: The invention relates to a method for coating surfaces with micro- and nanoparticles, the micro- and nanoparticles being chemically bonded to the surface, comprising the steps of pre-treatment of the surface with a plasma method, simultaneous or subsequent application of the micro- and nanoparticles to the surface, and subsequent fixation of the micro and nanoparticles on the surface using a plasma method, characterized in that the fixation of the micro- and nanoparticles takes place with the aid of anisothermal plasmas, the median electrical energy of which lies in the range of the bond dissociation energy of the micro- and nanoparticles, thus allowing the strength of the chemical bond between the surface and the micro- and nanoparticles to be variably set.
    Type: Application
    Filed: May 31, 2008
    Publication date: June 30, 2011
    Applicants: Ernst-Moritz-Arndt-Universitaet Greifswald, Inst Fuer Niedertemp.-Plasmaphysik E.V. Greifswald
    Inventors: Gerold Lukowski, Karsten Schroeder, Wolf-Dieter Juelich, Ruediger Foest, Klaus-Dieter Weltmann, Joerg Ehlbeck
  • Patent number: 6517786
    Abstract: A decomposition device and a method for decomposing gases with soot or other harmful substances has a processing station using dielectrically hindered discharge. The device has at least two electrodes, one of which is a porous and gas permeable electrode. In order to decompose the gas containing harmful substances, the gas is first introduced into a processing station in which the gas is subjected to plasma processing involving an alternate voltage supply, and from which the gas is let out. The gas is introduced through one end of the processing station formed by the two electrodes.
    Type: Grant
    Filed: January 10, 2000
    Date of Patent: February 11, 2003
    Assignee: Institute fuer Niedertemperatur-Plasmaphysik E. V. An der Ernst-Moritz-Arndt-Universitaet Greifswald
    Inventors: Walter Best, Johannes Peter Franziskus Conrads, Wolf-Dieter Franke, Siegfried Mueller, Wolfgang Reich