Abstract: The present invention relates to cytokine fusion proteins and to nucleic acid molecules encoding such cytokine fusion proteins. The present invention further relates to cells, non-human organisms. pharmaceutical compositions and kits comprising the cytokine fusion proteins or the nucleic acid molecules encoding them, as well as to their use as medicaments.

Abstract: A friction stir welding device and a friction stir welding method provide that an additional material is introduced into the gap between a rotating pin and a fixed shoulder. The pin and/or the shoulder includes a conveyor worm structure by which the additional material is transported to the workpiece.

Abstract: Method for producing a component system having a first component with a first component portion and a second component with a second component portion, including the following steps: connecting, in particular welding or soldering, the first component portion, which consists of an aluminum alloy, to the second component portion, which in particular consists of a naturally aged aluminum alloy, a copper alloy or an iron alloy, in particular a steel alloy, so as to form a connection seam; artificially aging the connection seam such that the yield strength of the connection seam is above the yield strength of the first component portion and/or of the second component portion; and deforming, in particular deep-drawing and/or stretch-drawing, the component system.

Abstract: The present invention relates to a method and a computer program product for generating an artifact-reduced voxel data record of an object. The artifact-reduced voxel data record of the object is generated with the aid of a computed tomography scanner. In some aspects of the present disclosure, a first image data record and a second image data record is generated by acquiring computed tomography images of the object. In still other aspects of the present disclosure, the artifact-reduced voxel data record of the object is generated with the aid of an image data reconstruction algorithm.

Abstract: The present invention provides a flexible high-density fiberboard which is essentially free of formaldehyde and isocyanates and comprises 70 to 90% by weight of straw fibers, and 30 to 10% by weight of a thermoplastic elastomer and one or more optional additive(s). Furthermore, the present invention provides a method for manufacturing such a flexible high-density fiberboard comprising the steps of providing straw fibers, providing a thermoplastic elastomer in powder form, optionally providing one or more additive(s), dry mixing the straw fibers, the thermoplastic elastomer powder and optionally the one or more additive(s), such that a mixture comprising 70 to 90% by weight of the straw fibers, and 30 to 10% by weight of the thermoplastic elastomer and one or more of the optional additive(s) is obtained, extruding the obtained mixture at a temperature such that the thermoplastic elastomer powder is in a molten state, and pressing the extruded mixture.

Abstract: An interferometer for areally measuring an optically smooth surface is presented, including means for illuminating a surface region with a plurality of discrete object waves from different directions and comprising means which, on a detector, superimpose object waves reflected at the surface onto a reference wave that is coherent with a plurality of object waves in order to form an interferogram. The interferometer is distinguished by virtue of it being configured to illuminate the surface with a plurality of object waves at the same time and produce the reference wave by way of a Fizeau beam splitter plate or a Fizeau objective, and by virtue of the interferometer including an interferometer stop that is arranged in the beam path upstream of the detector, and imaging optics, wherein the interferometer stop is situated within, or slightly outside of, the Fourier plane of the imaging optics and said interferometer stop filters the object waves reflected by the surface.

Abstract: A self-driving storage device for storing and/or transporting body components of motor vehicles, base modules of motor vehicles, or motor vehicles in a final or partially assembled state, the self-driving storage device comprising a base element and a support structure which is arranged on the base element, is designed to receive the body components or the motor vehicles in a final or partially assembled state, and has a plurality of storage spaces with movable storage base elements, wherein the storage device has a movement device which is arranged on the base element and is designed such that the storage device can be moved omnidirectionally in a self-driving manner, in a floor-bound manner.

Abstract: In a method for impregnating semi-finished fibrous products using resin as the impregnating means, winding or laying the semi-finished fibrous products in a plurality of layers on top of one another onto a receiving carrier is initially performed. Here, lower layers lie close to the receiving carrier, and upper layers lie more remote therefrom. The receiving carrier is configured so as to be permeable to the impregnating means. The impregnating means is then introduced through the receiving carrier into the semi-finished fibrous products, wherein the impregnating means initially permeates the lower layers and then permeates the upper layers of the semi-finished fibrous products.

Abstract: The invention relates to an N-heterocyclic carbene complex of general formulas I to IV (I) (II) (III) (IV), according to which A1 stands for NR2 or PR2, A2 stands for CR2 R2?, NR2, PR2, 0 or S, A3 stands for N or P, and C stands for a carbene carbon atom, ring B is an unsubstituted or a mono or poly-substituted 5 to 7-membered ring, substituents R2 and R2? stand, inter alia, for a linear or branched C1-Cw-alkyl group and, if N and N each stand for NR2 or PR2, are the same or different, M in formulas I, II, III or IV stands for Cr, Mo or W, X 1 or X2 in formulas I to IV are the same or different and represent, inter alia, C1-C1s carboxylates and C1-C1s-alkoxides, Y is inter alia oxygen or sulphur, Z is inter alia a linear or branched C1-Cw-alkylenoxy group, and R 1 and R1? in formulas I to IV are, inter alia, an aliphatic or aromatic group.

Abstract: The invention relates to methods and to devices for generating multispectral illuminating light having an addressable spectrum, for adaptive multispectral imaging and for capturing structural and/or topographical information of an object or of the distance to an object. The illuminating device comprises a multispectral light source and a modulator for temporal modulation of the individual spectral components of the multispectral light source having modulation frequencies. The multispectral light source comprises at least one light source having a continuous, quasi-continuous, or frequency comb spectrum and wavelength-dispersive means, or an assembly or array of monochromatic or quasi-monochromatic light sources having emission wavelengths or emission wavelength bands which are different from one another in each case.

Abstract: A driverless transport device for assembling a motor vehicle comprising a drivable base and a vehicle carrier coupled to the base and extending in a longitudinal direction, is configured and developed in terms of a flexible production using simple constructional means, in such a way that the vehicle carrier has actuatable receiving points for carrying the motor vehicle, the vehicle carrier can be moved along its longitudinal direction relative to the base by means of a guide device and can be tilted around an axis oriented orthogonally to the longitudinal direction, such that the at least partially assembled motor vehicle can drive off of the vehicle carrier on its own wheels when receiving points are released from the motor vehicle. The invention also relates to a method for unloading a motor vehicle from a driverless transport device that functions to assemble the motor vehicle.

Abstract: The present invention relates to a method and an apparatus for establishing residual stresses in objects, in particular in coated objects, and to a method and an apparatus for coating objects. The method comprises: impinging a surface (8) of the object (5) with laser light and generating a hole or a pattern of holes and/or locally heated points in the object (5); establishing the surface deformations by an optical deforming measuring method after the object (5) is impinged by laser light; establishing the residual stresses present in the object (5) from the measured surface deformations, wherein the generation of the hole pattern is carried out by an optical scanning apparatus which comprises an optical deflection and/or modulation arrangement for controllable deflection and/or modulation of the laser light, and/or a focusing arrangement for controllable focusing of the laser light.

Abstract: Provided is a method and tool for butt welding a first material piece of metal to a second material piece of metal at opposed longitudinal edges. The second material piece has a greater material thickness than the first material piece. The first material piece has a higher tensile strength and/or a higher inching temperature and/or a higher yield strength and/or a higher modulus of elasticity than the second material piece. A thickened longitudinal edge is provided at the first material piece. The thickening of the longitudinal edge is at least partly produced by at least simple folding, beading or winding of the first material piece or at least partly by folding the first material piece at its edge. The two material pieces are friction-stir welded at their front along the opposed longitudinal edges.

Abstract: The present invention provides a polypeptides comprising a heavy chain domain 2 (HD2) from IgM or IgE and at least one pharmaceutically active moiety, complexes thereof and their use for therapy and prophylaxis.

Abstract: Disclosed herein is a measuring probe and an arrangement for measuring spectral absorption, preferably in the infrared. Furthermore, the invention relates to a method for spectroscopically measuring absorption. The measuring probe may comprise a cutting apparatus configured to cut a slice or respectively flap off of a sample to be measured; a measuring gap configured to accommodate the sample slice; an optical window element for coupling measuring light into, or respectively out of the measuring gap; and an end reflector designed and arranged to reflect the measuring light propagated through the measuring gap back into the measuring gap. The arrangement for measuring spectral absorption may comprise the measuring probe, a light source and an apparatus for the spectral analysis of the measuring light coupled out of the measuring gap.

Abstract: Disclosed are methods and an assembly for robust one-shot interferometry, in particular for optical coherence tomography according to the spatial domain approach (SD-OCT) and/or according to the light-field approach. In one embodiment, the method and the assembly may be used for measurements on material and living tissue, for distance measurement, for 2D or 3D measurement with a finely structured light source imaged onto the object in a diffraction-limited way, or with spots thereof. The assembly may comprise an interferometer having object and reference arms and a detector for electromagnetic radiation. In other embodiments, during a detection process, a plurality of spatial interferograms may be formed by making an inclined and/or curved reference wavefront interfere with an object wavefront for each measurement point. The resulting spatial interferograms may be detected in a single detector frame and may be further evaluated via a computer program.

Abstract: An optical rotating device for injecting a laser beam may include deflection devices between which the injected laser beam may rotate in the optical rotating device, and an extraction device that may extract the laser beam after carrying out a predetermined number of rotations in the rotating device. The deflection devices may be arranged such that the position of the laser beam during extraction is dependent on the number of rotations carried out in the optical rotating device.

Abstract: The invention relates to an N-heterocyclic carbene complex of general formulas I to IV (I) (II) (III) (IV), according to which A1 stands for NR2 or PR2, A2 stands for CR2 R2?, NR2, PR2, 0 or S, A3 stands for N or P, and C stands for a carbene carbon atom, ring B is an unsubstituted or a mono or poly-substituted 5 to 7-membered ring, substituents R2 and R2? stand, inter alia, for a linear or branched C1-Cw-alkyl group and, if N and N each stand for NR2 or PR2, are the same or different, M in formulas I, II, III or IV stands for Cr, Mo or W, X 1 or X2 in formulas I to IV are the same or different and represent, inter alia, C1-C1s carboxylates and C1-C1s-alkoxides, Y is inter alia oxygen or sulphur, Z is inter alia a linear or branched C1-Cw-alkylenoxy group, and R 1 and R1? in formulas I to IV are, inter alia, an aliphatic or aromatic group.

Abstract: A method for the fabrication of thin-film transistors together with micromechanical components, other active electrical components or both on an amorphous or polycrystalline substrate includes disposing the thin-film transistors and the other components on different areas of the substrate.

Abstract: A thin-film transistor includes an oxidic semiconductor channel, a metallic or oxidic gate, drain and source contacts and at least one barrier layer positioned between the oxidic semiconductor channel and the drain and source contacts to inhibit an exchange of oxygen between the oxidic semiconductor channel and the drain and source contacts.