Patents Assigned to Universita' Degli Studi di Padova
  • Publication number: 20240226333
    Abstract: The present invention relates to a promoter sequence for efficient and sufficient expression of transgenes as well as to gene transfer vectors comprising said promoter sequence for use in therapy. In particular, the present invention relates to lentiviral vectors that provide gene therapy for pathological conditions of the central nervous system.
    Type: Application
    Filed: May 3, 2022
    Publication date: July 11, 2024
    Applicant: UNIVERSITÁ DEGLI STUDI DI PADOVA
    Inventors: Alessandra BIFFI, Valentina POLETTI
  • Patent number: 12028113
    Abstract: A polarization modulation method of photonic pulses, in particular for generating quantum cryptographic keys, ensures an optimum stability of the outgoing polarization states, and comprises the steps of: generating a plurality of photonic pulses with an unspecified polarization state obtained by the overlapping of both the horizontal and vertical polarization modes thereof, and routing them in a first polarization-maintaining fiber; splitting said horizontal and vertical polarization modes and routing them in respective terminals of a second polarization-maintaining fiber forming a ring, whereby they travel such ring clockwise and counter-clockwise respectively, or vice versa; inducing a respective phase modulation (oe, ol) of both said polarization modes, in one point of said ring which is spaced from said terminals by optical paths having different length along said ring, thereby a polarization-maintaining fiber delay line is determined; and recombining said polarization modes in one single photonic pulse b
    Type: Grant
    Filed: October 20, 2020
    Date of Patent: July 2, 2024
    Assignee: UNIVERSITÀ DEGLI STUDI DI PADOVA
    Inventors: Giuseppe Vallone, Costantino Agnesi, Marco Avesani, Paolo Villoresi
  • Publication number: 20240129040
    Abstract: A polarization modulation method of photonic pulses includes: generating a plurality of photonic pulses with an unspecified polarization state obtained by the overlapping of both the horizontal and vertical polarization modes thereof, and routing them in a first polarization-maintaining fiber; splitting the horizontal and vertical polarization modes and routing them in respective terminals of a second polarization-maintaining fiber forming a ring, whereby they travel clockwise and counter-clockwise respectively, or vice versa; inducing a respective phase modulation of both polarization modes, in one point of the ring which is spaced from said terminals by optical paths having different length along said ring, thereby a polarization-maintaining fiber delay line is determined; and recombining the polarization modes in one single photonic pulse beam, and routing the resulting beam through the first polarization-maintaining fiber, by obtaining, at the output thereof, a polarization state of the pulses depending u
    Type: Application
    Filed: October 20, 2020
    Publication date: April 18, 2024
    Applicant: UNIVERSITÀ DEGLI STUDI DI PADOVA
    Inventors: Giuseppe VALLONE, Costantino AGNESI, Marco AVESANI, Paolo VILLORESI
  • Patent number: 11863080
    Abstract: An active-clamped isolated SEPIC DC-DC power converter (ACISC) to convert a DC voltage to supply a variety of DC loads. The single-ended primary-inductor converter (SEPIC) of the ACISC may be configured to perform both buck and boost converter functions. The ACISC of this disclosure may be configured to operate over a wide input voltage range to provide an output voltage for DC electronic loads supplied by the power converter. In the example of an automobile, a back-up twelve volt battery may output voltages to the ACISC over a wide voltage range, e.g., nine volts to eighteen volts. The wide input voltage range of the ACISC may be desirable when used as the converter for a back-up battery supply. The circuitry arrangement and component selection of the ACISC of this disclosure cause the power converter to operate in resonant DCM mode in the megahertz (MHz) frequency range.
    Type: Grant
    Filed: February 15, 2022
    Date of Patent: January 2, 2024
    Assignees: Infineon Technologies AG, Università Degli Studi di Padova
    Inventors: Stefano Cabizza, Giorgio Spiazzi, Cristian Garbossa
  • Publication number: 20230318472
    Abstract: An active-clamped isolated SEPIC DC-DC power converter (ACISC) to convert a DC voltage to supply a variety of DC loads. The single-ended primary-inductor converter (SEPIC) of the ACISC may be configured to perform both buck and boost converter functions. The ACISC of this disclosure may be configured to operate over a wide input voltage range to provide an output voltage for DC electronic loads supplied by the power converter. In the example of an automobile, a back-up twelve volt battery may output voltages to the ACISC over a wide voltage range, e.g., nine volts to eighteen volts. The wide input voltage range of the ACISC may be desirable when used as the converter for a back-up battery supply. The circuitry arrangement and component selection of the ACISC of this disclosure cause the power converter to operate in resonant DCM mode in the megahertz (MHz) frequency range.
    Type: Application
    Filed: February 15, 2022
    Publication date: October 5, 2023
    Applicant: Università degli Studi di Padova
    Inventors: Stefano Cabizza, Giorgio Spiazzi, Cristian Garbossa
  • Publication number: 20230249227
    Abstract: The present invention relates to a cleaning apparatus (100) for metal smallware, comprising: a washing chamber (1) apt to receive a solvent and at least one batch of metal smallware soiled with lubricant and configured to carry out a washing cycle to remove at least part of said lubricant from said batch of metal smallware soiled with lubricant by means of said solvent and; suction means (2) connected to said washing chamber (1) and configured to carry out a discharge cycle by sucking said gaseous mixture comprising air and solvent from said washing chamber (1); a main absorption column (4) having a first side (41) and a second side (42) opposite each other, and wherein said first side (41) is hydraulically connected to said suction means (2) so as to receive said gaseous mixture comprising air and solvent and said second side (42) is hydraulically connected to a supply duct (3) so as to receive an absorption liquid from the latter.
    Type: Application
    Filed: February 3, 2023
    Publication date: August 10, 2023
    Applicants: IFP Europe S.r.l., Università degli Studi di Padova
    Inventors: Alberto BERTUCCO, Elena BARBERA, Giacomo SABBADIN
  • Publication number: 20230193212
    Abstract: The invention relates to the field of gene therapy and more specifically to hematopoietic stem and progenitor cells that have been genetically modified to express functional progranulin. Suitably, HSPCs that have gene edited using CRISPR/Cas technology, or have been transduced with lentiviral gene delivery vehicles. The invention also relates to the use of such modified HSPCs in therapy. In particular, the invention relates to use of the modified progranulin expressing HSPCs in the prevention or treatment of a neurodegenerative disease mediated by dysfunctional progranulin expression, such as frontotemporal dementia (FTD).
    Type: Application
    Filed: May 6, 2021
    Publication date: June 22, 2023
    Applicants: ORCHARD THERAPEUTICS (EUROPE) LIMITED, UNIVERSITA DEGLI STUDI DI PADOVA, UNIVERSITA DEGLI STUDI DI PADOVA
    Inventors: Alessandra Biffi, Yuri Ciervo
  • Patent number: 11640483
    Abstract: A configurable hardware device comprises a configuration memory of a known total size, and a configurable fabric arranged for being configured according to information from the configuration memory and segmented in a static partition and at least one dynamic partition. A static partition is arranged for receiving a bit stream and a cryptographic nonce and comprises a read/write mechanism for interacting with the configuration memory. The received bit stream is stored in the configuration memory and used to configure an intended application in the dynamic partition. The static partition is arranged for computing, based on the cryptographic nonce, a checksum of the entire configuration memory and for outputting the checksum.
    Type: Grant
    Filed: April 23, 2019
    Date of Patent: May 2, 2023
    Assignees: UNIVERSITÀ DEGLI STUDI DI PADOVA, KATHOLIEKE UNIVERSITEIT LEUVEN
    Inventors: Md Masoom Rabbani, Mauro Conti, Nele Mentens, Jo Vliegen
  • Publication number: 20230126620
    Abstract: The present invention relates to a rapid method for the direct quantification of Aflatoxin M1 (AFM1) in a sample of milk. The invention also relates to a device and the use thereof in implementing said method.
    Type: Application
    Filed: March 23, 2021
    Publication date: April 27, 2023
    Applicant: UNIVERSITA' DEGLI STUDI DI PADOVA
    Inventors: Teofilo Vamerali, Giuseppe Barion, Stefano Tiozzo Netti
  • Patent number: 11628163
    Abstract: The present description relates to 1-piperidinepropionic acid or pharmaceutically acceptable salts thereof, or pharmaceutical compositions comprising it, for use in the treatment of chronic fibrosing diseases.
    Type: Grant
    Filed: March 9, 2018
    Date of Patent: April 18, 2023
    Assignee: Università degli Studi di Padova
    Inventors: Patrizia Pontisso, Alessandra Biasiolo, Andrea Cappon, Andrea Martini, Santina Quarta, Mariagrazia Ruvoletto, Cristian Turato, Gianmarco Villano
  • Publication number: 20230109623
    Abstract: A field kit for a death scene investigation includes: a first table of values corresponding to causes of death; a second table of values corresponding to a victim's history of mental illness; a third table of values corresponding to consistency between death scene evidence and a suicidal dynamic; a fourth table of values corresponding to a number of suicidal methods involved in the victim's death; a fifth table of values corresponding to a compatibility of suicidal methods and injuries to the victim with a suicidal dynamic; a sixth table of values corresponding to a presence of positive indicators of suicide; a seventh table of values corresponding to a classification of death between a death compatible with a suicide and a death incompatible with a suicide; a telecommunications device; and a computing device comprising a memory and a processor.
    Type: Application
    Filed: December 8, 2022
    Publication date: April 6, 2023
    Applicant: UNIVERSITA' DEGLI STUDI DI PADOVA
    Inventor: Massimo Montisci
  • Patent number: 11540768
    Abstract: Method for detecting biomechanical and functional parameters of the knee in a situation of performance stress, which comprises: a step for the set up of video recording means (1); a step for the set up of multiple optical markers (4) at specific landmark anatomic points (PA) of the foot and of the knee of a person; a step for the set up, at the plantar surface of the foot, of baropodometric means (5); a step for the acquisition, by means of the video recording means (1), of images of at least one reference action, and a step for the detection, by means of the baropodometric means (5), of baropodometric parameters; a step for calculating, from the baropodometric parameters, the coordinates of the center of pressure (COP) of the foot and of the constraining reaction force (FV) acting on the foot; a step for calculating a force arm (BF) given by the distance between the center of pressure (COP) and a reference point (PR) of the knee; a step for calculating a biomechanical parameter indicative of the valgus momen
    Type: Grant
    Filed: April 26, 2018
    Date of Patent: January 3, 2023
    Assignee: UNIVERSITA DEGLI STUDI DI PADOVA
    Inventors: Zimi Sawacha, Davide Pavan, Federica Cibin, Giorgio Sbrocco, Annamaria Guiotto, Claudio Cobelli, Fabiola Spolaor
  • Publication number: 20220276177
    Abstract: The present invention relates to a colorimetric sensor for measuring pH based on the H coordinate of the HSV color space.
    Type: Application
    Filed: August 3, 2020
    Publication date: September 1, 2022
    Applicant: UNIVERSITÀ DEGLI STUDI DI PADOVA
    Inventors: Luca CAPPELLIN, Paolo PASTORE, Denis BADOCCO, Andrea PASTORE
  • Publication number: 20220265626
    Abstract: The invention concerns the use of 1-Piperidinpropionic acid or salts thereof, for the treatment of tumors that express SerpinB3.
    Type: Application
    Filed: July 23, 2020
    Publication date: August 25, 2022
    Applicant: UNIVERSITA' DEGLI STUDI DI PADOVA
    Inventors: Patrizia Pontisso, Alessandra Biasiolo, Andrea Martini, Santina Quarta, Mariagrazia Ruvoletto, Cristian Turato, Gianmarco Villano
  • Publication number: 20220185969
    Abstract: The invention provides a modified bio-related substance that shows further prolonged half-life in blood and further improved stability in the blood of living organisms. In particular, the invention provides a conjugate of a block polymer and a bio-related substance, which conjugate is represented by the following formula (I), wherein each symbol is as described herein.
    Type: Application
    Filed: April 15, 2019
    Publication date: June 16, 2022
    Applicants: NOF CORPORATION, UNIVERSITA' DEGLI STUDI DI PADOVA
    Inventors: Hiroki YOSHIOKA, Midori HIRAI, Masaki KAMIYA, Gianfranco PASUT
  • Patent number: 11298348
    Abstract: Sarcoglycanopathies are autosomal recessive diseases caused by mutations in the one of the genes coding for any sarcoglycans (SG). The inventors previously showed that the application of small molecules developed to rescue ?F508-CFTR trafficking, and known as CFTR correctors, improved the maturation of several ?-sarcoglycan mutants that were consequently rescued at the plasma membrane (WO 014086687). Now, the inventors show that some specific CFTR correctors provide additive and even synergic effect when administered in combination.
    Type: Grant
    Filed: January 10, 2019
    Date of Patent: April 12, 2022
    Assignees: INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MÉDICALE), UNIVERSITE D'EVRY-VAL-D'ESSONNE, GENETHON, UNIVERSITA 'DEGLI STUDI DI PADOVA
    Inventors: Isabelle Richard, Dorianna Sandona
  • Publication number: 20210267197
    Abstract: The invention relates to new peptides and their use as pesticides. In particular, these peptides have been advantageously used for the treatment of vine peronospora (downy mildew).
    Type: Application
    Filed: June 28, 2019
    Publication date: September 2, 2021
    Applicant: UNIVERSITA' DEGLI STUDI DI PADOVA
    Inventors: Marta De Zotti, Francesco Favaron, Luca Sella
  • Publication number: 20210255160
    Abstract: The invention refers to a method of preparing of a silage good having improved quality, to an ensiling process employing the method or the silage good, and an apparatus of preparing of a silage good having improved quality.
    Type: Application
    Filed: June 21, 2019
    Publication date: August 19, 2021
    Applicants: KWS SAAT SE & CO. KGAA, UNIVERSITA DEGLI STUDI DI PADOVA
    Inventors: Igino ANDRIGHETTO, Giorgio MARCHESINI, Lorenzo SERVA, Matteo GAZZIERO, Sandro TENTI, Massimo MIRISOLA, Elisabetta GARBIN, Barbara CONTIERO, Daniel GRANDIS
  • Publication number: 20210241924
    Abstract: A method for contacting a predetermined entity based on a death event classification includes: assigning a numeric value to a first partial score based on the method which caused the subject's death; assigning a numeric value to a second partial score based on the subject's history of mental illness; assigning a numeric value to a third partial score based on consistency of the death scene evidence with suicidal dynamics; assigning a numeric value to a fourth partial score based on the number of means that caused the subject's death; assigning a numeric value to a fifth partial score based on the compatibility of means and injuries with suicidal dynamics; summing the partial scores to obtain a total score; adding a correction factor if at least one suicide indicator is present; and classifying the death event. If the death event is classified as incompatible with suicide, the predetermined entity is notified.
    Type: Application
    Filed: January 30, 2020
    Publication date: August 5, 2021
    Applicant: UNIVERSITA' DEGLI STUDI DI PADOVA
    Inventor: Massimo Montisci
  • Patent number: 11008293
    Abstract: The invention relates to a class of 5-carboxamide-2-thiobarbituric acid derivatives which inhibits human type II topoisomerase (topoII) enzyme and to use thereof as medicaments especially for blocking the proliferation of cancer cells and treating cancer. The invention also provides a method for the manufacture of the 5-carboxamide-2-thiobarbituric acid derivatives.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: May 18, 2021
    Assignees: UNIVERSITÀ DEGLI STUDI DI PADOVA, FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
    Inventors: Marco De Vivo, Jose Antonio Ortego Martinez, Claudia Sissi, Jose Manuel Arencibia Jimenez