Patents Assigned to UNIVERSITA ' DELGI STUDI DI PARMA
  • Derivatives of nicotinic acid N-oxide, their preparation and their use as inhibitors of enzyme 3-hydroxyanthranilate-3, 4-dioxygenase
    Patent number: 9487486
    Abstract: A derivative of nicotinic acid N-oxide is described having formula (I): that acts as inhibitor of enzyme 3-hydroxyanthranilate-3,4-dioxygenase (3HAO), and is thus able to reduce QUIN biosynthesis in vivo under excitotoxic or pathological conditions, said compound being at the same time also chemically stable towards auto-oxidation.
    Type: Grant
    Filed: November 4, 2015
    Date of Patent: November 8, 2016
    Assignees: UNIVERSITY OF MARYLAND, BALTIMORE, UNIVERSITA DELGI STUDI DI PARMA
    Inventors: Robert Schwarcz, Gabriele Costantino, Laura Amori
  • Derivatives of nicotinic acid N-oxide, their preparation and their use as inhibitors of enzyme 3-hydroxyanthranilate-3, 4-dioxygenase
    Patent number: 9260394
    Abstract: A derivative of nicotinic acid N-oxide is described having formula (I): that acts as inhibitor of enzyme 3-hydroxyanthranilate-3,4-dioxygenase (3HAO), and is thus able to reduce QUIN biosynthesis in vivo under excitotoxic or pathological conditions, said compound being at the same time also chemically stable towards auto-oxidation.
    Type: Grant
    Filed: January 19, 2011
    Date of Patent: February 16, 2016
    Assignees: UNIVERSITY OF MARYLAND, BALTIMORE, UNIVERSITA' DELGI STUDI DI PARMA
    Inventors: Robert Schwarcz, Gabriele Costantino, Laura Amori
  • Use of a Coordination Complex or Compound for the Measurement of Temperature
    Publication number: 20130301679
    Abstract: Use for measuring temperatures of a coordination complex presenting formula I, wherein M1, M2, M3, M4, M5 are chosen, each independently of the others, in the group consisting of: CuI, AgI, AuI, PdII; n is equal to the sum of the oxidation states of M1, M2, M3, M4, M5 minus 3; II represents a respective portion of each tridentate ligand having the formula III in which R1 is chosen in the group consisting of: Ph, C1-C4 alkyl, halo-alkyl C1-C4 substituted phenyl; R2 is chosen in the group consisting of: Ph, C1-C4 alkyl, C1-C4 halo-alkyl-, substituted phenyl; R3 is chosen in the group consisting of: C3-C18 alkyl, benzyl, substituted benzyl, C1-C20 hydroxy-alkyl, C1-C20 alkoxy silane.
    Type: Application
    Filed: October 26, 2011
    Publication date: November 14, 2013
    Applicants: UNIVERSITA ' DELGI STUDI DI PARMA, ALMA MATER STUDIORUM- UNIVERSITA' DI BOLOGNA
    Inventors: Sara Bonacchi, Marco Montalti, Luca Prodi, Nelsi Zaccheroni, Francesco Zerbetto, Matteo Calvaresi, Daniele Alessandro Cauzzi