Abstract: The present invention relates to a nucleic acid construct allowing to drives the expression of a transcription factor in rod cells or cone cells thereby silencing the expression of a gene which mutated form is responsible for a retinal dystrophy and its medical use, relative expression vector, host cell, viral particle and pharmaceutical composition.
Type:
Application
Filed:
December 21, 2018
Publication date:
August 8, 2024
Applicant:
UNIVERSITA DI NAPOLI FEDERICO II
Inventors:
Enrico Maria SURACE, Salvatore BOTTA, Elena MARROCCO, Nicola DE PRISCO
Abstract: Provided is a hydrogel. The hydrogel includes a liquid and a plurality of microfibers suspended in the liquid as an entangled network. The entangled network includes physically entangled microfibers that are mechanically interlocked.
Type:
Grant
Filed:
May 31, 2016
Date of Patent:
April 14, 2020
Assignees:
THE TRUSTEES OF PRINCETON UNIVERSITY, UNIVERSITÀ DI NAPOLI “FEDERICO II” DIPARTIMENTO DI INGEGNERIA CHIMICA, DEI MATERIALI E DELLA PRODUZIONE INDUSTRIALE
Inventors:
Janine K. Nunes, Antonio Perazzo, Stefano Guido, Howard A. Stone
Abstract: Novel pharmaceutical therapeutic compositions and methods for using same for the treatment of pain experienced by an individual are provided. The compositions contain at least one member selected from among anandamide and palmitylethanolamide.
Type:
Grant
Filed:
January 22, 2002
Date of Patent:
December 2, 2003
Assignees:
Neurosciences Research Foundation, Inc., Universita di Napoli Federico II
Inventors:
Antonio Calignano, Giovanna La Rana, Andrea Guiffrida, Daniele Piomelli