Patents Assigned to Universita' Federico II
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Publication number: 20250143240Abstract: Use of a non-woven fabric comprising polylactic acid fibers for inoculation of to be mycorrhized plants.Type: ApplicationFiled: August 25, 2022Publication date: May 8, 2025Applicant: ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNAInventors: Pamela LEONARDI, Alessandra ZAMBONELLI, Federico PULIGA
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Publication number: 20250135003Abstract: There is described a scintillator for electromagnetic radiation therapy comprising a nanotube being functionalized with a plurality of singlet oxygen photosensitizers configured to form singlet oxygen upon excitation by means of an electromagnetic radiation; and a plurality of ligands configured to stabilize the scintillator within a fluid comprising water and/or to minimize interaction with biomolecules present within the fluid.Type: ApplicationFiled: October 8, 2024Publication date: May 1, 2025Applicants: UNIVERSITA' DEGLI STUDI DI MILANO - BICOCCA, BAR-ILAN UNIVERSITYInventors: Angelo MONGUZZI, Valeria SECCHI, Marcello CAMPIONE, Shai RAHIMIPOUR, Sudipta SENAPATI
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Publication number: 20250128013Abstract: The safety device (10) comprises a valve body provided with an internal duct (11) and a closure member (14), able to be displaced between an opening position of said internal duct (11) and a closing position of said internal duct (11) as a function of the pressure detected by a pressure sensor (16). A mechanical ventilation circuit (100) comprising such safety device (10) is also described.Type: ApplicationFiled: February 2, 2023Publication date: April 24, 2025Applicants: UNIVERSITA' DEGLI STUDI DI FIRENZE, AZIENDA OSPED ALIERO-UNIVERSITARIA CAREGGIInventors: Yari BARDACCI, Leonardo BOCCHI, Lorenzo CASATI, Samuele BALDASSINI, Stefano BAMBI, Laura RASERO
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Publication number: 20250127539Abstract: A device for the placement of organic tissue, in particular endocrine tissue, includes a hollow tubular base element configured to house in a seat at least one portion of the organic tissue, a pushing element which inserted on the inside of the base element and coupled to it in a sliding manner; wherein the base element is configured to at least partially penetrate a target tissue. The base element further includes a first opening, which is arranged in a distal zone towards a first end and is configured to let out and, hence, position the organic tissue in the target tissue through the action of the pushing element.Type: ApplicationFiled: September 7, 2022Publication date: April 24, 2025Applicants: IRCCS AZIENDA OSPEDALIERO - UNIVERSITARIA DI BOLOGNA, ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNAInventors: Paolo Casadio, Renato Seracchioli, Diego Raimondo, Benedetta Orsini, Alessandro Arena, Antonio Raffone
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Publication number: 20250115742Abstract: A process is disclosed for making a printed plant-based leather, a printed plant-based leather obtainable by the process, and the use of the plant-based leather, such as in outer garments, including shoes, boots, jackets, belts, accessories, such as bags and wallets, and seat covers, such as for automotive and furniture applications. The process and the composition involve plant-based wastes of one or more sources and wherein each waste contains at least one of the following biopolymers: cellulose, hemicellulose, pectin, lignin, aliphatic polyesters, and starch.Type: ApplicationFiled: April 15, 2022Publication date: April 10, 2025Applicants: PLHYDE, INC., UNIVERSITÀ DEGLI STUDI DI MILANO-BICOCCAInventors: Rebecca MINK, Roberto SIMONUTTI, Michele MAURI
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Publication number: 20250099379Abstract: The present invention relates to the field of the formulation of bioactive compounds. More specifically, it relates to the use of wet silica-based polymers obtained with the sol-gel technology for the incorporation and prolonged release of an active ingredient, preferably of a protein for topical use, for example in the treatment of chronic ulcers and for the improvement of the trophism of skin appendages. The composition of the invention has several advantages, in particular it has a long permanence in the application point, by avoiding that the composition drips or dries up in contact with air.Type: ApplicationFiled: January 18, 2023Publication date: March 27, 2025Applicant: UNIVERSITÀ DEGLI STUDI DI PADOVAInventors: Patrizia PONTISSO, Margherita MORPURGO, Gian Paolo FADINI, Mattia ALBIERO, Alessandra BIASIOLO, Santina QUARTA, Mariagrazia RUVOLETTO, Cristian TURATO, Gianmarco VILLANO
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Publication number: 20250101491Abstract: Method for diagnosing Alzheimer's disease in an individual, comprising the steps of providing at least one serum sample derived from the individual, providing at least one preparation of phage clones expressing peptides that mimic conformational epitopes of the A?-42 peptide, reacting said at least one serum sample with said at least one preparation of phage clones expressing peptides that mimic conformational epitopes of A?-42, so that antibodies that may be present in said serum and are directed against the A?-42 peptide bind to the peptides expressed by phage clones of said preparation of phage clones, detecting, by real-time PCR technique, the quantity of phage clones of said preparation to which said antibodies have bound, and determining, based on the quantity of phage clones of said preparation to which said antibodies have bound, whether the individual from whom said serum sample was derived suffers from Alzheimer's disease.Type: ApplicationFiled: January 27, 2023Publication date: March 27, 2025Applicant: UNIVERSITA’ DEGLI STUDI DI MESSINAInventors: Salvatore GUGLIELMINO, Maria Giovanna RIZZO, Domenico FRANCO, Laura Maria DE PLANO, Sabrina CONOCI, Salvatore CUZZOCREA, Emanuela ESPOSITO, Irene PATERNITI, Michela CAMPOLO
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Publication number: 20250102440Abstract: The present invention refers to a method for detecting and/or determining the amount of ergothioneine (EG) in a sample using surface-enhanced Raman scattering (SERS) spectroscopy. This method involves the use of an internal standard such as 5-amino-2-mercaptobenzimidazole. (5A2MBI).Type: ApplicationFiled: September 17, 2024Publication date: March 27, 2025Applicant: Università degli Studi di TriesteInventors: Stefano FORNASARO, Alois BONIFACIO, Gioia VENTUROTTI
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Patent number: 12253970Abstract: compression and search process on a data set based on multiple strategies, including: extracting a set of raw data and transforming it into a sequence of symbols, manipulating the sequence by combining data structures and one or more (optionally a multiplicity of) compression strategies to obtain compressed and efficiently searchable data, recording the compressed and efficiently searchable data on storage media.Type: GrantFiled: October 6, 2022Date of Patent: March 18, 2025Assignee: UNIVERSITA' DI PISAInventors: Paolo Ferragina, Giovanni Manzini, Giorgio Vinciguerra
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Patent number: 12253548Abstract: A system for monitoring and analyzing electrical operating parameters of a load in an electric network includes a smart socket placed in series between the load and the electric network. The smart socket includes a voltage detection module that measures a voltage value in the electric network between the ends of the load, a current detection module in the electric network that measures a current value adsorbed by the load, and a control unit connected to the voltage detection module and to the current detection module. In particular, the control unit comprises a neural network arranged to carry out a training comprising the steps of definition of a number n of events association, to each event Ei of a number mi, of patterns pij of predetermined current and/or voltage trends, extrapolation of characteristic parameters cik distinguishing the pattern pij associated with the classified event Ei.Type: GrantFiled: December 31, 2020Date of Patent: March 18, 2025Assignee: UNIVERSITÀ DEGLI STUDI DI FIRENZEInventors: Fabio Corti, Giacomo Talluri, Francesco Grasso, Marco Somma, Libero Paolucci
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Patent number: 12253355Abstract: A system (50) for tracking an object (1) comprises a magnetic field source (10) configured to be fixed to this object (1); a magnetometric data collection unit (20) that uses magnetic field sensors (22) fixed at predetermined positions on a support (23) to form an array (21), and that includes a sensor control unit (25) for controlling the magnetic field sensors (22); a data processing unit (30) configured to receive the magnetic field data from the sensor control unit (25) and to calculate from these data position coordinates of the magnetic field source (10) with respect to the array (21) forming a vector of such position coordinates which minimizes the distance between magnetic field values expected at the sensor positions (22) and magnetic field values collected by the collection unit (20), wherein the magnetic field source (10) is arranged to generate a local magnetic field (4), at the magnetic field sensors (22), of intensity set between 5 and 500 microtesla, so that the magnetic field sensors (22) deteType: GrantFiled: July 22, 2021Date of Patent: March 18, 2025Assignee: UNIVERSITÀ DEGLI STUDI DI SIENAInventors: Valerio Biancalana, Piero Chessa, Roberto Cecchi, Marco Mandala′, Domenico Prattichizzo
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Publication number: 20250076294Abstract: A rapid test device for the detection of SARS-CoV-2 viruses and for the relative antibody production including a substrate of the lateral flow immunochromatographic assay divided into 5 regions: a first reception area to receive the biological sample (“Sample Deposition”); a second area where the first reaction takes place between an analyte and the molecule used for its specific identification (“Conjugation pad”); a third area where the signal amplification uses the addition of the gold nanoparticles (“Signal amplification”); a fourth test area (“Test line”) and a fifth control area (“Control Line”) in which a second and third immunoreaction takes place, providing a visual reading of the test result by a window and two results visible by a colored strip. The sample deposition area comprises a filter having porosity of about 200 nm-1 ?m.Type: ApplicationFiled: July 25, 2022Publication date: March 6, 2025Applicants: UNIVERSITA' DEGLI STUDI MAGNA GRAECIA DI CATANZARO, POLITECNICO DI TORINOInventors: Natalia MALARA, Cristina POTRICH, Cecilia PEDERZOLLI, Lorenzo LUNELLI, Candido Fabrizio PIRRI, Enzo Mario DI FABRIZIO, Francesca FRASCELLA, Lucia NAPIONE, Marzia QUAGLIO, Alessandro CHIADO'
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Patent number: 12239667Abstract: The present invention concerns the therapeutic use of extracellular vesicles isolated from a genetically modified cell line over-expressing SerpinB3. In particular, said therapeutic use aimed at the treatment of acute pathologies characterized by ischemic or inflammatory tissue damage or by cell injury due to oxidative stress, such as cardiac, cerebral, intestinal, renal or limb ischaemia. Further examples of use consist of the preservation of transplant organs, including heart, lung, liver, bladder, pancreas and intestine. In a further aspect the invention relates to the use of a pharmaceutical composition comprising extracellular vesicles isolated from a genetically modified cell line over-expressing SerpinB3 and a pharmaceutically acceptable vehicle.Type: GrantFiled: February 14, 2020Date of Patent: March 4, 2025Assignee: UNIVERSITÀ DEGLI STUDI DI PADOVAInventors: Patrizia Pontisso, Maurizio Muraca, Alessandra Biasiolo, Santina Quarta, Mariagrazia Ruvoletto, Gianmarco Villano
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Publication number: 20250066399Abstract: The present invention refers to a process for the preparation of P(?O) heteroatom derivatives of the dibenzooxaphos-phacycles compounds of formula 6H-cibenzo [c.e] [1.2] oxaphosphinine 6-oxide (DOPO) and dibenzo [d.f] [1.3.2] dioxaphosphepine 6-oxide (BPPO). It also refers to a process for the preparation of polymeric formulations containing it: and a process for the preparation of a flame retardant polymer using the P(?O) heteroatom derivatives as monomer.Type: ApplicationFiled: November 24, 2022Publication date: February 27, 2025Applicants: AIMPLAS ASOCIACIÓN DE INVESTIGACIÓN DE MATERIALES PLÁSTICOS Y CONEXAS, UNIVERSITÀ CA’ FOSCARI VENEZIAInventors: Ludovico AGOSTINIS, Stefan GHINCOLOV, Marco BORTOLUZZI
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Publication number: 20250066411Abstract: The present invention relates to new glycomimetic molecules which selectively bind to the L-SIGN receptor, finding application in the medical field and, in particular, in the prevention and treatment of viral infections, in the immunotherapy of liver tumors and in the treatment of immune diseases.Type: ApplicationFiled: October 24, 2024Publication date: February 27, 2025Applicants: UNIVERSITA’ DEGLI STUDI DI MILANO, UNIVERSITÉ GRENOBLE ALPES, COMMISSARIAT A L’ÉNERGIE ATOMIQUE ET AUX ÉNERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Anna BERNARDI, Sara POLLASTRI, Clara DELAUNAY, Michel THÉPAUT, Franck FIESCHI, Gianluca CAVAZZOLI
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Publication number: 20250057779Abstract: Hybrid nanoparticles consisting of a polymeric component encapsulating cationic liposomes and/or lipoplexes comprising a cationic lipid and a helper lipid are described, wherein the polymeric component constitutes at least the 80% by weight with respect to the total material constituting the nanoparticles.Type: ApplicationFiled: December 22, 2022Publication date: February 20, 2025Applicants: POLITECNICO DI TORINO (75%), UNIVERSITA' DEGLI STUDI DI TORINO (25%)Inventors: Valeria Chiono, Clara Mattu, Letizia Nicoletti, Camilla Paoletti, Silvia Maria Angela Arpicco, Barbara Stella
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Patent number: 12226215Abstract: The invention provides a composition for a conductive polymeric material suitable for the production of electrodes for recording electrophysiological signals, such as electrocardiogram (EGG), electromyogram (EMG), electroencephalogram (EEG), etc., and signals related to the impedance variation of the body or skin, both deriving from active and passive measures (for example, breathing, electrodermal response, etc.). For this purpose a formulation containing FEDOT and ionic liquids has been developed. The formulation according to the invention can be used generically in the context of detecting bioelectric signals and can be applied on wearable items, in particular in fabric, such as for example garments of different shapes, so as to be in direct contact with the areas of the body subject to detection.Type: GrantFiled: April 29, 2020Date of Patent: February 18, 2025Assignees: Giuseppe USAI, ALMA MATER STUDIORUM—UNIVERSITA' DI BOLOGNA, UNIVERSITA' DEGLI STUDI DI CAGLIARIInventors: Giuseppe Arnaldo Usai, Erika Scavetta, Isacco Gualandi, Beatrice Fraboni, Marta Tessarolo, Annalisa Bonfiglio, Danilo Pani, Eleonora Sulas
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Publication number: 20250049888Abstract: The invention relates to novel Negr1 protein fragments having ALK-inhibiting or ALK-reducing activity and to the nucleic acids encoding therefor, as well as to the use of the Negr1 protein, its fragments and the nucleic acids encoding therefor in the therapeutic treatment of ALK-related diseases such as cancer and tauopathies.Type: ApplicationFiled: December 21, 2022Publication date: February 13, 2025Applicants: FONDAZIONE TELETHON ETS (70%), UNIVERSITA' DEGLI STUDI DI TRENTO (30%)Inventors: Giovanni Piccoli, Francesca Pischedda
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Publication number: 20250041221Abstract: The invention relates to a nanoparticle comprising at least one cationic lipid, at least one neutral lipid, and at least one pH sensitive lipid which differs from said cationic lipid, which can be used as a vector for the transport and release of nucleic acids within cells.Type: ApplicationFiled: December 2, 2022Publication date: February 6, 2025Applicants: Universite Claude Bernard Lyon 1, Centre National de la Recherche Scientifique, Hospices Civils De Lyon, INSERM (Institut National de la Santé et de la Recherche Médicale), Universita Degli Studi Di VeronaInventors: Giovanna Lollo, Valentina Andretto, David Kryza, Eyad Al Mouazen, Mathieu Repellin, Stéphanie Briancon, Laurent Schaeffer, Jacquier Arnaud, Laurent Coudert
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Patent number: D1072803Type: GrantFiled: June 23, 2021Date of Patent: April 29, 2025Assignee: Università Degli Studi Di TrentoInventors: Fabio Massacci, Matthias Caretta Crichlow, Francesco Minna, Gabriele Fadini, Yangzhe Kong, Teyi Kung, Riccardo Sparagna