Patents Assigned to UNIVERSITAET DES SAARLANDES CAMPUS SAARBRUECKEN
  • Selective CYP11B1 inhibitors for the treatment of cortisol dependent diseases
    Patent number: 9394290
    Abstract: The present invention relates to compounds which selectively inhibit CYP11B1. Preferably, the compounds of the present invention do not substantially inhibit CYP11B2. Moreover, the compounds of the present invention do not substantially inhibit CYP17 and/or CYP19, either. Amongst other applications of the compounds of the present invention, they can be used for the treatment of Cushing's syndrome or metabolic disease.
    Type: Grant
    Filed: October 21, 2011
    Date of Patent: July 19, 2016
    Assignee: UNIVERSITAET DES SAARLANDES CAMPUS SAARBRUECKEN
    Inventors: Rolf Hartmann, Ulrike Hille, Christina Zimmer, Carsten A. Vock, Qingzhong Hu