Patents Assigned to Universitaet Ulm
  • Patent number: 10384230
    Abstract: The invention relates to a method for producing a substrate structured by nanowires, characterized in that no lubricant and no lithographic resist mask is used in the method, and only by moving a donor substrate having nanowires relative to a substrate and by locally tribological properties on the surface of the substrate, a specified number of nanowires is deposited selectively at locally defined points of the substrate. The invention further relates to a substrate that can be produced using the method according to the invention, and which selectively contains a specified number of nanowires on a surface at locally defined points. The invention further relates to the use of the substrate according to the invention in microelectronics, microsystems technology, and/or micro-sensor systems.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: August 20, 2019
    Assignee: UNIVERSITÄT ULM
    Inventors: Steffen Strehle, Daniel Markus Rosskopf, Andreas Magnus Probst
  • Patent number: 10345400
    Abstract: The invention concerns a method for the hyperpolarisation of 13C nuclear spin in a diamond, comprising an optical pumping step, in which colour centre electron spins in the diamond are optically pumped. The method further comprises a transfer step in which the polarisation of a long-lived state of the colour centre electron spins is transferred to 13C nuclear spins in the diamond via a long-range interaction.
    Type: Grant
    Filed: April 7, 2014
    Date of Patent: July 9, 2019
    Assignee: UNIVERSITAET ULM
    Inventors: Fedor Jelezko, Jianming Cai, Martin Plenio, Alex Retzker, Boris Naydenov, Ilai Schwarz
  • Patent number: 9980942
    Abstract: The present invention relates generally to methods and pharmaceutical compositions for rejuvenating hematopoietic stem cells and progenitor cells from blood, intestinal tissue and dermal tissue by administration of at least one inhibitor of a GT-Pase, such as Cdc42 GTPase.
    Type: Grant
    Filed: April 30, 2013
    Date of Patent: May 29, 2018
    Assignees: CHILDREN'S HOSPITAL MEDICAL CENTER, UNIVERSITAET ULM
    Inventors: Hartmut Geiger, Maria Carolina Florian, Yi Zheng
  • Publication number: 20170348727
    Abstract: The invention relates to a method for producing a substrate structured by nanowires, characterized in that no lubricant and no lithographic resist mask is used in the method, and only by moving a donor substrate having nanowires relative to a substrate and by locally tribological properties on the surface of the substrate, a specified number of nanowires is deposited selectively at locally defined points of the substrate. The invention further relates to a substrate that can be produced using the method according to the invention, and which selectively contains a specified number of nanowires on a surface at locally defined points. The invention further relates to the use of the substrate according to the invention in microelectronics, microsystems technology, and/or micro-sensor systems.
    Type: Application
    Filed: December 14, 2015
    Publication date: December 7, 2017
    Applicant: UNIVERSITÄT ULM
    Inventors: Steffen STREHLE, Daniel Markus ROSSKOPF, Andreas Magnus PROBST
  • Publication number: 20160206699
    Abstract: The present invention relates to the field of cell-based therapeutics. Specifically, the invention is concerned with a composition comprising a macrophage overexpressing interleukin 10 (IL-10) from transfected IL-10 encoding mRNA for use as a medicament. Moreover, a method for manufacturing a medicament for treating and/or preventing inflammation or a disease or disorder associated therewith comprising the steps of obtaining a macrophage from a sample of said subject, transfecting mRNA encoding IL-10 into said macrophage, and formulating said macrophage in a composition suitable for administration to the said subject, whereby the medicament is manufactured. Finally, a kit is provided for manufacturing such a medicament.
    Type: Application
    Filed: March 15, 2016
    Publication date: July 21, 2016
    Applicants: Ruprecht-Karls-Universität Heidelberg, Universität Ulm
    Inventors: Ziya KAYA, Hugo KATUS, Oliver ZIMMERMANN, Wolfgang ROTTBAUER, Jan TORZEWSKI
  • Patent number: 9315558
    Abstract: The present invention relates to the field of cell-based therapeutics. Specifically, the invention is concerned with a composition comprising a macrophage overexpressing interleukin 10 (IL-10) from transfected IL-10 encoding mRNA for use as a medicament. Moreover, a method for manufacturing a medicament for treating and/or preventing inflammation or a disease or disorder associated therewith comprising the steps of obtaining a macrophage from a sample of said subject, transfecting mRNA encoding IL-10 into said macrophage, and formulating said macrophage in a composition suitable for administration to the said subject, whereby the medicament is manufactured. Finally, a kit is provided for manufacturing such a medicament.
    Type: Grant
    Filed: November 14, 2011
    Date of Patent: April 19, 2016
    Assignees: RUPRECHT-KARLS-UNIVERSITÄT HEIDELBERG, UNIVERSITÄT ULM
    Inventors: Ziya Kaya, Hugo Katus, Oliver Zimmermann, Wolfgang Rottbauer, Jan Torzewski
  • Publication number: 20150265594
    Abstract: The invention relates to novel strategies for the treatment of cancer patients based on a combination of an opioid receptor agonist and an anticancer compound.
    Type: Application
    Filed: October 8, 2013
    Publication date: September 24, 2015
    Applicant: UNIVERSITÄT ULM
    Inventors: Claudia Friesen, Erich Miltner
  • Patent number: 9005886
    Abstract: The present invention discloses a method for cryopreservation of human spermatozoa: the method comprises providing spermatozoa free from seminal liquid; mixing the spermatozoa with vitrification medium, wherein the main cryoprotectant agent is 0.1-0.3 M sucrose; placing the sample inside straws and rapidly freezing them; refrigerating the straws with no need of liquid N2; and devitrifying the sample in a medium of the present invention. The present invention furthermore discloses a portable kit that makes easy to implement the method, said kit comprising vitrification and devitrification solutions in the volumes required to develop the method and the physical support to carry out the same, i.e. the straws. The use of this kit is also disclosed for the treatment of disorders related to reproductive failures.
    Type: Grant
    Filed: February 16, 2011
    Date of Patent: April 14, 2015
    Assignees: Universidad de La Frontera, Universitaet Ulm
    Inventors: Raul Sanchez Gutierrez, Jennie Risopatron Gonzalez, Mabel Schulz Rubilar, Evgenia Isachenko, Vladimir Isachenko
  • Patent number: 8901175
    Abstract: The use of opioids or opioid mimetics is suggested for the manufacture of a medicament for the treatment of resistant cancer patients.
    Type: Grant
    Filed: January 29, 2009
    Date of Patent: December 2, 2014
    Assignee: Universität Ulm
    Inventors: Erich Miltner, Claudia Friesen, Andreas Alt
  • Patent number: 8835573
    Abstract: The invention relates to a composite system comprising at least one biodegradable blend, containing at least one biodegradable block copolyester urethane (PEU) and also at least one polyhydroxyalkanoate (PHA), possibly a filler comprising a polysaccharide and/or derivatives thereof and also possibly further biocompatible additives. Composite systems of this type are used for producing molded articles, molded parts or extrudates. Furthermore, the invention relates to possibilities for using the composite system.
    Type: Grant
    Filed: November 28, 2008
    Date of Patent: September 16, 2014
    Assignee: Universität Ulm
    Inventors: Hartmut Seliger, Hans Häberlein
  • Publication number: 20140255988
    Abstract: DNA encoding a monomeric variant of red fluorescent protein eqFP611 comprising an amino acid sequence selected from the group consisting of SEQ ID No. 1, SEQ ID No. 3 and SEQ ID No. 5. DNA comprising a nucleotide sequence selected from the group consisting of SEQ ID No. 2, SEQ ID No. 4 and SEQ ID No. 6.
    Type: Application
    Filed: January 27, 2014
    Publication date: September 11, 2014
    Applicant: Universität Ulm
    Inventors: Jörg Wiedenmann, Simone Kredel, Franz Oswald, Gerd Ulrich Nienhaus
  • Publication number: 20130157250
    Abstract: The present invention discloses a method for cryopreservation of human spermatozoa: the method comprises providing spermatozoa free from seminal liquid; mixing the spermatozoa with vitrification medium, wherein the main cryoprotectant agent is 0.1-0.3 M sucrose; placing the sample inside straws and rapidly freezing them; refrigerating the straws with no need of liquid N2; and devitrifying the sample in a medium of the present invention. The present invention furthermore discloses a portable kit that makes easy to implement the method, said kit comprising vitrification and devitrification solutions in the volumes required to develop the method and the physical support to carry out the same, i.e. the straws. The use of this kit is also disclosed for the treatment of disorders related to reproductive failures.
    Type: Application
    Filed: February 16, 2011
    Publication date: June 20, 2013
    Applicants: UNIVERSITAET ULM, UNIVERSIDAD DE LA FRONTERA
    Inventors: Raul Sanchez Gutierrez, Jennie Risopatron Gonzalez, Mabel Schulz Rubilar, Evgenia Isachenko, Vladimir Isachenko
  • Publication number: 20120312353
    Abstract: A semiconductor component includes at least one electrode arrangement, the electrode arrangement having at least two electrodes, at least one electrode of which is an electrode including diamond. The semiconductor component has at least one monolithically integrated solar cell as energy source for the at least one electrode arrangement. The semiconductor component may be used for example in hydrogen production by electrolysis, in electroanalysis and also in water treatment.
    Type: Application
    Filed: July 19, 2010
    Publication date: December 13, 2012
    Applicant: Universitaet Ulm
    Inventors: Joachim Kusterer, Erhard Kohn
  • Publication number: 20120243509
    Abstract: The invention relates to a method for communicating intended information between a sender and at least one receiver in a communication system. The method comprises providing a plurality of elements to be sent from the sender to the receiver, the plurality of elements being in a first order; sending to the receiver the elements in a second order, the second order representing the intended information; receiving the plurality of elements; determining whether an order in which the elements have been received is different from the first order; if the order in which the elements have been received is different from the first order, determining an information based on the order in which the elements have been received; and if the order in which the elements have been received is the second order, the information determined is the intended information.
    Type: Application
    Filed: November 15, 2010
    Publication date: September 27, 2012
    Applicants: UNIVERSITÄT ULM, AALBORG UNIVERSITET
    Inventors: Petar Popovski, Zoran Utkovski
  • Publication number: 20120189813
    Abstract: A process for manufacturing a TEM-lamella includes mounting (51) a plate shaped substrate having a thickness in a support, manufacturing (53) a first, strip-shaped recess on a first side of the substrate under a first angle to the support by means of a particle beam, and manufacturing (55) a second strip-shaped recess on a second side of the substrate under a second angle to the support by means of a particle beam, such that the first and the second strip-shaped recess mutually form an acute or right angle, and between them form an overlap region of lesser thickness. The lamella has a thicker rim region and a thinner central region, with a first strip-shaped, recess on a first side of the lamella and a second strip-shaped recess on a second side of the lamella, wherein the first and the second strip-shaped recess mutually form an acute or right angle, and between them form an overlap region having a thickness of below 100 nm.
    Type: Application
    Filed: July 28, 2011
    Publication date: July 26, 2012
    Applicants: CARL ZEISS NTS GMBH, UNIVERSITAET ULM
    Inventors: Lorenz Lechner, Ute Kaiser, Johannes Biskupek
  • Publication number: 20120107244
    Abstract: Monomeric eqFP611 variants exhibit red fluorescent properties and DNA encoding monomeric eqFP611 variants.
    Type: Application
    Filed: November 26, 2009
    Publication date: May 3, 2012
    Applicant: Universität Ulm
    Inventors: Jörg Wiedenmann, Simone Kredel, Franz Oswald, Gerd Ulrich Nienhaus
  • Patent number: 8126536
    Abstract: In a method for determining the pelvic inlet plane of the pelvic bone, which is defined by the following three points of the pelvic bone: point A: spina iliaca anterior superior left point B: spina iliaca anterior superior right point C: symphysis pubis, by non-invasive determination of the position of one of the two points A or B and point C, in order to also be able to carry out this determination whenever point A or point B is not accessible, it is proposed that the position of the following points of the pelvic bone be additionally determined non-invasively: point D: spina iliaca posterior superior left point E: spina iliaca posterior superior right, and that the position of the pelvic inlet plane be calculated from the position of the non-invasively determined points A or B, C, D and E.
    Type: Grant
    Filed: September 4, 2008
    Date of Patent: February 28, 2012
    Assignees: Aesculap AG, Universitaet Ulm
    Inventors: Josef Kozak, Peter Keppler
  • Publication number: 20110265876
    Abstract: The present invention relates to novel pyridine compounds that can be used as anchoring ligands in metal-based sensitizing dyes of dye sensitized solar cells (DSCS). The dyes comprising the polypyridine compounds exhibit improved light harvesting ability and lead to increased conversion efficiencies, in particular in thin TiO2 film devices.
    Type: Application
    Filed: November 11, 2009
    Publication date: November 3, 2011
    Applicants: UNIVERSITÄT ULM, ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Shaik Mohammad Zakeeruddin, Cédric Klein, Mohammad Khaja Nazeeruddin, Michael Graetzel, Amaresh Mishra, Markus Fischer, Peter Bäuerle
  • Publication number: 20110270011
    Abstract: The use of opioids or opioid mimetics is suggested for the manufacture of a medicament for the treatment of resistant cancer patients.
    Type: Application
    Filed: January 29, 2009
    Publication date: November 3, 2011
    Applicant: Universität Ulm
    Inventors: Erich Miltner, Claudia Friesen, Andreas Alt
  • Publication number: 20110211604
    Abstract: The present invention relates to a surface-emitting semiconductor laser having a vertical resonator, comprising a substrate base section (1) and a mesa (M) arranged on and/or at the substrate base section, the mesa substantially comprising, viewed perpendicular to the substrate base section: at least one part of a first doting region (2) facing the substrate base section, at least one part of a second doping region (4) facing away from the substrate base section, and an active region (3) arranged between the first and the second doping regions, said active region having at least one active layer (A) with a laser-emitting zone, emitting substantially perpendicular to the active layer, characterized in that the mesa (M) comprises in at least one partial section of the side flank thereof at least one constriction (E).
    Type: Application
    Filed: May 5, 2009
    Publication date: September 1, 2011
    Applicant: UNIVERSITÄT ULM
    Inventor: Ralf-Hendrik Roscher