Patents Assigned to UNIVERSITAT AUGSBURG
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Publication number: 20220212194Abstract: Various aspects of the present invention relate to the control and manipulation of fluidic species, for example, in microfluidic systems. In one set of embodiments, droplets may be sorted using surface acoustic waves. The droplets may contain cells or other species. In some cases, the surface acoustic waves may be created using a surface acoustic wave generator such as an interdigitated transducer, and/or a material such as a piezoelectric substrate. The piezoelectric substrate may be isolated front the microfluidic substrate except at or proximate the location where the droplets arc sorted, e.g., into first or second microfluidic channels. At such locations, the microfluidic substrate may be coupled to the piezoelectric substrate (or other material) by one or more coupling regions. In some cases, relatively high sorting rates may be achieved, e.g., at rates of at least about 1,000 Hz, at least about 10,000 Hz, or at least about 100,000 Hz, and in some embodiments, with high cell viability after sorting.Type: ApplicationFiled: December 14, 2021Publication date: July 7, 2022Applicants: President and Fellows of Harvard College, Universität AugsburgInventors: David A. Weitz, Thomas Franke, Achim Wixforth, Lothar Schmid, Jeremy Agresti, Adam R. Abate
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Patent number: 11229911Abstract: Various aspects of the present invention relate to the control and manipulation of fluidic species, for example, in microfluidic systems. In one set of embodiments, droplets may be sorted using surface acoustic waves. The droplets may contain cells or other species. In some cases, the surface acoustic waves may be created using a surface acoustic wave generator such as an interdigitated transducer, and/or a material such as a piezoelectric substrate. The piezoelectric substrate may be isolated from the microfluidic substrate except at or proximate the location where the droplets are sorted, e.g., into first or second microfluidic channels. At such locations, the microfluidic substrate may be coupled to the piezoelectric substrate (or other material) by one or more coupling regions. In some cases, relatively high sorting rates may be achieved, e.g., at rates of at least about 1,000 Hz, at least about 10,000 Hz, or at least about 100,000 Hz, and in some embodiments, with high cell viability after sorting.Type: GrantFiled: January 2, 2019Date of Patent: January 25, 2022Assignees: President and Fellows of Harvard College, Universität AugsburgInventors: David A. Weitz, Thomas Franke, Achim Wixforth, Lothar Schmid, Jeremy Agresti, Adam R. Abate
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Patent number: 10570361Abstract: Various aspects of the present invention relate to the control and manipulation of fluidic species, for example, in microfluidic systems. In one set of embodiments, droplets may be sorted using surface acoustic waves. The droplets may contain cells or other species. In some cases, the surface acoustic waves may be created using a surface acoustic wave generator such as an interdigitated transducer, and/or a material such as a piezoelectric substrate. The piezoelectric substrate may be isolated from the microfluidic substrate except at or proximate the location where the droplets are sorted, e.g., into first or second microfluidic channels. At such locations, the microfluidic substrate may be coupled to the piezoelectric substrate (or other material) by one or more coupling regions. In some cases, relatively high sorting rates may be achieved, e.g., at rates of at least about 1,000 Hz, at least about 10,000 Hz, or at least about 100,000 Hz, and in some embodiments, with high cell viability after sorting.Type: GrantFiled: May 24, 2017Date of Patent: February 25, 2020Assignees: President and Fellows of Harvard College, Universität AugsburgInventors: David A. Weitz, Thomas Franke, Achim Wixforth, Lothar Schmid, Jeremy Agresti, Adam R. Abate
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Publication number: 20190211293Abstract: Various aspects of the present invention relate to the control and manipulation of fluidic species, for example, in microfluidic systems. In one set of embodiments, droplets may be sorted using surface acoustic waves. The droplets may contain cells or other species. In some cases, the surface acoustic waves may be created using a surface acoustic wave generator such as an interdigitated transducer, and/or a material such as a piezoelectric substrate. The piezoelectric substrate may be isolated from the microfluidic substrate except at or proximate the location where the droplets are sorted, e.g., into first or second microfluidic channels. At such locations, the microfluidic substrate may be coupled to the piezoelectric substrate (or other material) by one or more coupling regions. In some cases, relatively high sorting rates may be achieved, e.g., at rates of at least about 1,000 Hz, at least about 10,000 Hz, or at least about 100,000 Hz, and in some embodiments, with high cell viability after sorting.Type: ApplicationFiled: January 2, 2019Publication date: July 11, 2019Applicants: President and Fellows of Harvard College, Universität AugsburgInventors: David A. Weitz, Thomas Franke, Achim Wixforth, Lothar Schmid, Jeremy Agresti, Adam R. Abate
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Patent number: 9695390Abstract: Various aspects of the present invention relate to the control and manipulation of fluidic species, for example, in microfluidic systems. In one set of embodiments, droplets may be sorted using surface acoustic waves. The droplets may contain cells or other species. In some cases, the surface acoustic waves may be created using a surface acoustic wave generator such as an interdigitated transducer, and/or a material such as a piezoelectric substrate. The piezoelectric substrate may be isolated from the microfluidic substrate except at or proximate the location where the droplets are sorted, e.g., into first or second microfluidic channels. At such locations, the microfluidic substrate may be coupled to the piezoelectric substrate (or other material) by one or more coupling regions. In some cases, relatively high sorting rates may be achieved, e.g., at rates of at least about 1,000 Hz, at least about 10,000 Hz, or at least about 100,000 Hz, and in some embodiments, with high cell viability after sorting.Type: GrantFiled: August 23, 2011Date of Patent: July 4, 2017Assignees: President and Fellows of Harvard College, Universität AugsburgInventors: David A. Weitz, Thomas Franke, Achim Wixforth, Lothar Schmid, Jeremy Agresti, Adam R. Abate
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Publication number: 20100180101Abstract: The invention relates to a method for executing computer usable program code or a program made up of program parts on a multi-core processor (1) with a multiplicity of execution units (21, 22, 23, 24), each of which comprises a local memory (201) and at least one processing unit (202) communicatively linked to the local memory, wherein each of the execution units (21, 22, 23, 24) is connected to a communications network (30) for data exchange. One or more program parts are stored in at least some of the local memories (201) of the majority of execution units (21, 22, 23, 24). Execution of a program part is performed by the processing unit (202) of the particular execution unit (21, 22, 23, 24) that has the program part stored in its local memory (201).Type: ApplicationFiled: January 11, 2010Publication date: July 15, 2010Applicant: UNIVERSITAT AUGSBURGInventors: Wolfgang Trumler, Sascha Uhrig
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Patent number: 7396408Abstract: This invention relates to a method for the production of diamond films with low misorientation through the deposition of diamond on a film system, whereby the film system exhibits a substrate film made of monocrystalline silicon or silicon carbide, at least one buffer film arranged on that, and at least one metal film made of a refractory metal arranged on that, whereby the diamond is deposited on the at least one metal film.Type: GrantFiled: May 3, 2004Date of Patent: July 8, 2008Assignee: Universität AugsburgInventors: Matthias Schreck, Stefan Gsell, Bernd Stritzker
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Publication number: 20070084398Abstract: This invention relates to a method for the production of diamond films with low misorientation through the deposition of diamond on a film system, whereby the film system exhibits a substrate film made of monocrystalline silicon or silicon carbide, at least one buffer film arranged on that, and at least one metal film made of a refractory metal arranged on that, whereby the diamond is deposited on the at least one metal film.Type: ApplicationFiled: May 3, 2004Publication date: April 19, 2007Applicant: UNIVERSITAT AUGSBURGInventors: Matthias Schreck, Stefan Gsell, Bernd Stritzker