Patents Assigned to UNIVERSITAT DE VALÉNCIA, ESTUDI GENERAL
  • Patent number: 11740245
    Abstract: The present invention proposes a novel method for the detection of circulating histones H3 and H2B in plasma from sepsis or septic shock (SS) patients, based on mass spectrometry-based methods, in particular based on multiple reaction monitoring targeted mass spectrometry (MRM-MS). Such methods allow quantification of histones using an internal standard and show strong specificity and sensitivity values.
    Type: Grant
    Filed: November 6, 2017
    Date of Patent: August 29, 2023
    Assignees: Centro de Investigación Biomédica en Red (CIBER-ISCIII), Fundación INCLIVA, Universitat de Valencia Estudi General
    Inventors: José Luis García Giménez, Carlos Romá Mateo, Federico V. Pallardó Calatayud
  • Patent number: 11730751
    Abstract: Provided herein are methods and compositions related to treating motor neuron diseases, such as ALS, in a subject by administering to the subject (e.g., orally administering to the subject) a composition comprising nicotinamide riboside and/or pterostilbene.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: August 22, 2023
    Assignees: UNIVERSITAT DE VALÈNCIA-ESTUDI GENERAL, FUNDACIÓN UNIVERSIDAD CATÓLICA DE VALENCIA SAN VICENTE MÁRTIR, Elysium Health, Inc.
    Inventors: José Maria Estrela Ariguel, José Enrique De La Rubia Orti, Ryan Dellinger
  • Patent number: 11662347
    Abstract: A method for the diagnosis of systemic lupus erythematosus (SLE) based on an interfacial process of antigen-antibody molecular recognition, specifically between anti-Ro52 and Ro52 protein, in a piezoelectric resonator, for application in the diagnosis of autoimmune diseases such as SLE.
    Type: Grant
    Filed: June 29, 2018
    Date of Patent: May 30, 2023
    Assignees: UNIVERSITAT POLITECNICA DE VALENCIA, INSTITUTO DE INVESTIGACION SANITARIA LA FE—FUNDACION PARA LA INVESTIGACION DEL HOSPITAL UNIVERSITARIO Y POLITECNICO LA FE DE LA COMUNIDAD VALENCIANA, UNIVERSITAT DE VALENCIA ESTUDI GENERAL
    Inventors: Noelle Marine Do Nascimento, David Gimenez Romero, Sergi Benat Morais Ezquerro, Angel Maquieira Catala, Augusto Miguel Juste Dolz, Elena Grau Garcia, Rosa Puchades Pla, Jose Andres Roman Iborra
  • Patent number: 10577266
    Abstract: The present invention refers to an anaerobic process with filtration procedure for wastewater treatment at room temperature, that comprises: continuously feeding at least one anaerobic reactor, with previously sieved wastewater and feeding biodegradable organic waste—BOW—also previously sieved, said reactor being coupled to at least one gasified filtration membrane, with recirculation of biogas from the reactor, carrying out the anaerobic digestion of the organic fraction contained in the mixture of wastewater and the BOW, in the reactor, obtaining a treated mixture and filtering the mixture treated in the reactor, in at least one filtration tank through the gasified membrane under conditions such that the relationship between the biogas recirculated per square meter of membrane, and time unit, and the wastewater filtered—SGDp—is the minimum value allowed by the solid concentration in a treatment plant.
    Type: Grant
    Filed: March 30, 2017
    Date of Patent: March 3, 2020
    Assignees: FCC AQUALIA, S.A., UNIVERSITAT POLITÈCNICA DE VALÈNCIA, UNIVERSITAT DE VALÈNCIA ESTUDI GENERAL
    Inventors: Frank Rogalla, Jose Ramón Vázquez Padín, Emérita Jiménez Douglas, Freddy Durán Pinzón, Aurora Seco Torrecillas, Alberto Bouzas Blanco, Josep Ribes Bertomeu, María Victoria Ruano García, Joaquín Serralta Sevilla, Ángel Robles Martínez, Juan Bautista Giménez García, José Ferrer Polo
  • Patent number: 10508266
    Abstract: A method is for prevention and/or biological control of wilt caused by Ralstonia solanacearum, by use of suitable bacteriophages. In addition a method uses the structural characterisation, genome sequence and activity of three specific lytic bacteriophages of R. solanacearum. Podovirus presents an elevated stability between 4° C. and 30° C. in an aqueous medium in the absence of a host. As a result of the high level of stability, lytic activity, elevated specificity towards R. solanacearum and the absence of activity against the microbiota associated with the plants to be protected, bacteriophages are used for the biological control of R. solanacearum in river courses and irrigation water, as well as in a method for preventing and/or controlling the wilt produced by the bacteria, in which at least one of the bacteriophages, or combinations thereof, are delivered to the plants and/or the soil in the irrigation water.
    Type: Grant
    Filed: May 24, 2016
    Date of Patent: December 17, 2019
    Assignees: UNIVERSITAT DE VALÈNCIA (ESTUDI GENERAL), INSTITUTO VALENCIANO DE INVESTIGACIONES AGRARIAS (IVIA)
    Inventors: Elena González Biosca, María Milagros López González, María Belén Álvarez Ortega
  • Publication number: 20190127251
    Abstract: The present invention refers to an anaerobic process with filtration procedure for wastewater treatment at room temperature, that comprises: continuously feeding at least one anaerobic reactor, with previously sieved wastewater and feeding biodegradable organic waste—BOW—also previously sieved, said reactor being coupled to at least one gasified filtration membrane, with recirculation of biogas from the reactor, carrying out the anaerobic digestion of the organic fraction contained in the mixture of wastewater and the BOW, in the reactor, obtaining a treated mixture and filtering the mixture treated in the reactor, in at least one filtration tank through the gasified membrane under conditions such that the relationship between the biogas recirculated per square meter of membrane, and time unit, and the wastewater filtered—SGDp—is the minimum value allowed by the solid concentration in a treatment plant.
    Type: Application
    Filed: March 30, 2017
    Publication date: May 2, 2019
    Applicants: FCC AQUALIA, S.A., UNIVERSITAT POLITÈCNICA DE VALÈNCIA, UNIVERSITAT DE VALÈNCIA ESTUDI GENERAL
    Inventors: Frank ROGALLA, Jose Ramón VÁZQUEZ PADÍN, Emérita JIMÉNEZ DOUGLAS, Freddy DURÁN PINZÓN, Aurora SECO TORRECILLAS, Alberto BOUZAS BLANCO, Josep RIBES BERTOMEU, María Victoria RUANO GARCÍA, Joaquín SERRALTA SEVILLA, Ángel ROBLES MARTÍNEZ, Juan Bautista GIMÉNEZ GARCÍA, José FERRER POLO
  • Publication number: 20110091371
    Abstract: Soluble homo and heterometallic coordination polymers based on the oxalate ligand and method for obtaining spinels from them. Homo or heterometallic coordination polymers comprising at least one oxalate ligand are characterised by comprising also at least one organic molecule that can stabilise extended structures of metal complexes by the formation of supramolecular interactions so that this polymer is substantially water-soluble and insoluble in organic solvents.
    Type: Application
    Filed: April 24, 2009
    Publication date: April 21, 2011
    Applicant: Universitat De Valencia, Estudi General
    Inventors: Eugenio Coronado Miralles, Carlos Marti Gastaldo, Jose Ramon Galan Mascaros
  • Publication number: 20100047212
    Abstract: Use of the PEDF factor to induce cell regeneration. The present invention refers to the use of the molecule PEDF for the manufacture of medicines to activate processes included in the group of regenerative processes, such as skin regeneration, wound healing, cell therapy for cardiac, neural, or hematopoietic regeneration. It also refers to the manufacture/use of pharmaceutical compounds that contain an efficient quantity of the PEDF factor for stem cell self-renewal.
    Type: Application
    Filed: February 16, 2007
    Publication date: February 25, 2010
    Applicants: UNIVERSITAT DE VALENCIA ESTUDI GENERAL, UNIVERSIDAD DE CASTILLA-LA MANCHA
    Inventors: Isabel Fariñas Gómez, Celia Andreu Agulló, Sacremento Rodriguez Ferrón, Carmen Ramirez Castillejo, Pilar Sánchez Gómez, Helena Mira Aparicio, Julio Éscribano Martinez, Francisco Sánchez Sánchez, José Daniel Aroca Aguilar
  • Publication number: 20100001803
    Abstract: The invention is characterized in that it comprises a plurality of impedances (R2, C3, R4, R5) and at least one operational amplifier (51, 52), and means (53) for connecting a resistive sensor (Rs) to the electronic circuit (50) such that, once the resistive sensor has been connected to the electronic circuit, a resulting electronic circuit is obtained that consists of the electronic circuit and the resistive sensor connected thereto, the input impedance (Zinp) of which corresponds to that of a variable capacitance as a function of the resistive sensor (Rs). A capacitative input impedance that can very as a function of a sensor is obtained.
    Type: Application
    Filed: November 14, 2007
    Publication date: January 7, 2010
    Applicant: UNIVERSITAT DE VALÉNCIA, ESTUDI GENERAL
    Inventor: Diego Ramírez Muñoz