Patents Assigned to Universitat Duisburg-Essen
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Patent number: 11462129Abstract: A surgical simulator having at least two holding elements on a support surface, wherein a bore for receiving a bearing pin is present laterally on the holding elements at least one location, and at least one bow is arranged coaxially with respect to the bearing pin which extends on a circular or rectangular line about the support surface, wherein, by a coaxial movement of the bow about the circular or rectangular line, a work field of variable size can be adjusted, and, by the movement of the bow as frame element on the holding elements, the support surface can be spanned in an arc shape, and the use of such a surgical simulator for medical and veterinary training purposes.Type: GrantFiled: September 6, 2017Date of Patent: October 4, 2022Assignee: UNIVERSITÄT DUISBURG-ESSENInventor: Ivan Novokhatskiy
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Patent number: 11149067Abstract: The present invention pertains to an improved chemical synthesis method for Ahp-cyclodepsipeptides which allows straight forward and easy synthesis of tailor-made Ahp-cyclodepsipeptides. The invention further provides Ahp-cyclodepsipeptides for use as HTRA protease inhibitors and their medical use.Type: GrantFiled: May 14, 2018Date of Patent: October 19, 2021Assignee: UNIVERSITÄT DUISBURG-ESSENInventors: Markus Kaiser, Steffen Köcher, Juliana Rey, Jens Bongard, Michael Ehrmann, Sarah Resch
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Publication number: 20200211590Abstract: A heat assisted magnetic recording disk drive comprises a magnetic recording media with a heat sink layer including at least a material being defined by the general structure Mn+1AXn, wherein M is a transition metal, A is an A-group element, X is C or N or a mixture of C and N, and n is a positive integer, or a material defined by the general structure Mn+1AXn, wherein M is a transition metal, X is one or both of C and N, and n is a positive integer, or a mixture of the materials being defined by the general structure Mn+1AXn and the material defined by the general structure Mn+1Xn, wherein the crystal structure of the materials is hexagonal with repeated M-X-M (quasi 2D) atomic layers. The atomic layers are stacked along the {right arrow over (c)}-axis that is oriented substantially parallel to the surface normal of the heat sink layer.Type: ApplicationFiled: September 6, 2016Publication date: July 2, 2020Applicants: UNIVERSITÄT DUISBURG-ESSENInventors: Dieter WELLER, Ruslan SALIKHOV, Ulf WIEDWALD, Michael FARLE
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Publication number: 20200111536Abstract: The present invention is directed towards a tubular nanosized magnetic wire, wherein the nanosized magnetic wire comprises: a tubular magnetic shell surrounding a longitudinal axis of the wire, at least one region of the tubular magnetic shell is capable of providing a 360° magnetic domain wall, wherein the 360° magnetic domain wall is self-stabilizing and has a magnetization going from a parallel alignment to a perpendicular alignment and to a parallel alignment with regards to the wire axis. The present invention also provides a practical method capable of making a tubular nanosized magnetic wire with a self-stabilizing, 360° magnetic domain wall. The present invention also relates to the use of the tubular nanosized magnetic wire in a racetrack memory device.Type: ApplicationFiled: October 4, 2018Publication date: April 9, 2020Applicant: Universität Duisburg-EssenInventors: Benjamin ZINGSEM, Michael FARLE, Thomas FEGGELER, Irene IGLESIAS
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Patent number: 10614902Abstract: The present invention is directed towards a tubular nanosized magnetic wire, wherein the nanosized magnetic wire comprises: a tubular magnetic shell surrounding a longitudinal axis of the wire, at least one region of the tubular magnetic shell is capable of providing a 360° magnetic domain wall, wherein the 360° magnetic domain wall is self-stabilizing and has a magnetization going from a parallel alignment to a perpendicular alignment and to a parallel alignment with regards to the wire axis. The present invention also provides a practical method capable of making a tubular nanosized magnetic wire with a self-stabilizing, 360° magnetic domain wall. The present invention also relates to the use of the tubular nanosized magnetic wire in a racetrack memory device.Type: GrantFiled: October 4, 2018Date of Patent: April 7, 2020Assignee: Universität Duisburg-EssenInventors: Benjamin Zingsem, Michael Farle, Thomas Feggeler, Irene Iglesias
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Patent number: 10507107Abstract: An implantable device for improving or remedying valvular incompetence, comprising a sealing body and at least one anchoring element (2) fastened thereto, by means of which the sealing body is able to be fastened in the heart, preferably in the atrium of the heart, wherein the sealing body comprises at least one cavity (6), which is also able to be filled with a fluid after implanting the sealing body and preferably not able to be emptied independently, and wherein, furthermore preferably, the sealing body remains expanded with constant volume during the cardiac phases as a result of the filling, characterized in that a plurality of cavities (6) are disposed about a main body (1) of the sealing body lying in the direction of longitudinal extent of the sealing body, or a single cavity (6) surrounds a main body (1) of the sealing body lying in the direction of longitudinal extent of the sealing body, wherein the main body (1) is embodied as a tube which is able to be bent out of the linear extent thereof and inType: GrantFiled: May 10, 2016Date of Patent: December 17, 2019Assignees: Universität Duisburg-Essen, coramaze technologies GmbHInventors: Niklas Maximilian Nathe, Till Neumann, Torsten Scheuermann
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Publication number: 20190206282Abstract: A surgical simulator having at least two holding elements on a support surface, wherein a bore for receiving a bearing pin is present laterally on the holding elements at least one location, and at least one bow is arranged coaxially with respect to the bearing pin which extends on a circular or rectangular line about the support surface, wherein, by a coaxial movement of the bow about the circular or rectangular line, a work field of variable size can be adjusted, and, by the movement of the bow as frame element on the holding elements, the support surface can be spanned in an arc shape, and the use of such a surgical simulator for medical and veterinary training purposes.Type: ApplicationFiled: September 6, 2017Publication date: July 4, 2019Applicant: UNIVERSITÄT DUISBURG-ESSENInventor: Ivan NOVOKHATSKIY
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Patent number: 10207038Abstract: The disclosure relates to a pump for implantation into a vessel or a heart, with the pump being introduced in a first state into the vessel or heart in order then be functionally changed over to a second state in the vessel or in the heart, having a drive part and a delivery part, where the drive part is not functional in the first state and becomes functional as a result of the changeover to the second state, wherein the drive part has an electric motor, where the electric motor is embodied as a wet rotor, and where, in the first state, the rotor of the electric motor and the stator of the electric motor are arranged so as to be separate from one another, and where the rotor of the electric motor is moved into the stator of the electric motor in the second state, where the rotor can drive the delivery part in the second state.Type: GrantFiled: June 10, 2015Date of Patent: February 19, 2019Assignee: UNIVERSITAT DUISBURG-ESSENInventor: Till Neumann
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Publication number: 20190010484Abstract: The present invention relates to a method for predicting the degree of radiosensitivity of a cell by determining the number of prompt double-strand breaks (prDSBs) and predicting the degree of radiosensitivity of the cell based on the number of prDSBs. The present invention relates furthermore to a method for predicting the degree of radiosensitivity of a cell by determining the number of thermally labile sugar lesion-dependent double-strand breaks (tlDSBs) and predicting the degree of radiosensitivity of the cell based on the number of tlDSBs.Type: ApplicationFiled: August 4, 2016Publication date: January 10, 2019Applicant: Universität Duisburg-EssenInventor: George ILIAKIS
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Publication number: 20180360959Abstract: The present invention relates to an agent which inhibits Kallikrein-8 for use in the treatment or prevention of Alzheimer's disease and/or its precursor stages, as well as to methods, kits and uses relating thereto, including diagnostic tools.Type: ApplicationFiled: September 21, 2016Publication date: December 20, 2018Applicant: UNIVERSITÄT DUISBURG-ESSENInventors: Arne Herring, Kathy Keyvani
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Publication number: 20180354849Abstract: The invention provides an aerogel-concrete mixture, a high-performance aerogel concrete obtained therefrom, and a method for production thereof. The problem addressed by the present application is that of providing pressure-resistant but not very thermally conductive concretes, precast concrete components, screeds, screeds for precast components, (glassfibre-) reinforced concrete, fire protection panels, construction elements for thermal partition and blocks. The aerogel-concrete mixture contains: 10% to 85% by volume/m3 of aerogel pellets having a grain size in the range from 0.01 to 4 mm, 100 to 900 kg/m3 of inorganic hydraulic binder, 10% to 40% by weight based on the binder content of at least one silica gel suspension, 1% to 5% by weight based on the binder content of at least one plasticizer, 0.2% to 1% by weight based on the binder content of at least one stabilizer and 0% to 60% by volume/m3 of at least one lightweight aggregate.Type: ApplicationFiled: June 13, 2016Publication date: December 13, 2018Applicants: DEUTSCHES ZENTRUM FÜR LUFT-UND RAUMFAHRT E.V., UNIVERSITÄT DUISBURG-ESSENInventors: Barbara MILOW, Lorenz RATKE, Torsten WELSCH, Silvia FICKLER, Martina SCHNELLENBACH-HELD, Jan-Eric HABERSAAT
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Publication number: 20160184606Abstract: The present invention relates to a device for collimating electromagnetic radiation comprising a shielding structure at least partially surrounding a radiation source which has an opening in a transmission direction (A), a plurality of lamellae of a material that absorbs electromagnetic radiation which are positioned in the opening, and collimator channels between the lamellae which extend in the transmission direction (A), wherein the lamellae have a height (H) in the range of ?10 ?m to ?3000 ?m.Type: ApplicationFiled: June 6, 2013Publication date: June 30, 2016Applicants: Universität Duisburg-Essen, Technische Universität DortmundInventors: Dirk Flühs, Marion Eichmann
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Patent number: 9339803Abstract: In one aspect, catalytic membranes are described herein. In some embodiments, a catalytic membrane comprises a surface functionalized with a polymer, the polymer comprising cellulose solubilization functionalities and acid functionalities for the catalytic hydrolysis of cellulose and/or hemicellulose.Type: GrantFiled: October 31, 2012Date of Patent: May 17, 2016Assignees: Board of Trustees of the University of Arkansas, Universitat Duisburg-EssenInventors: Sumith Ranil Wickramasinghe, Xianghong Qian, Mathias Ulbricht, Qian Yang
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Patent number: 9074259Abstract: The invention relates to an in vitro method for predicting disease risks, progression of diseases, drug risks, success of treatment and for finding drug targets by looking for one or more genetic modifications in the promoter region of the CHK1 (CHEK1) gene on human chromosome 11q23, the genetic modifications being a substitution thymine for guanine in position ?1143 in the promoter of CHK1, of thymine for cytosine in position ?1400, a substitution of cytosine for thymine in position ?1453 or an insertion of one cytosine in position ?1454 and the genetic modifications being detected individually or in any combinations by way of known methods.Type: GrantFiled: November 1, 2012Date of Patent: July 7, 2015Assignee: UNIVERSITAT DUISBURG-ESSENInventors: Kathrin Riemann, Winfried Siffert
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Patent number: 8945431Abstract: The invention relates to a process for producing an electrically conductive, porous, silicon- and/or tin-containing carbon material which is suitable in particular for the production of an anode material, preferably for lithium ion batteries; in a first step of the process, preferably crystalline silicon nanoparticles and/or tin nanoparticles and/or silicon/tin nanoparticles are introduced into a matrix based on at least one organic polymer, being more particular dispersed therein, and subsequently, in a second step of the process, the resultant polymer matrix containing the silicon, tin and/or silicon/tin nanoparticles is carbonized to form carbon.Type: GrantFiled: July 14, 2009Date of Patent: February 3, 2015Assignee: Universität Duisburg-EssenInventors: Christof Schulz, Hartmut Wiggers
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Patent number: 8945611Abstract: The invention relates to dispersions of artificial oxygen carriers, wherein the dispersions contain capsules with reversible oxygen storage capacity, the capsules comprising an oxygen-permeable capsule material, that contains and/or encloses fluorinated, particularly perfluorinated hydrocarbons, preferably perfluorocarbons. The dispersions are particularly suitable as a blood substitute, preferably for the purpose of transfusion, e.g. in states of blood loss of the human or animal body, in particular following surgical interventions, accidents, injuries etc, or for the prophylactic treatment and/or treatment by therapy of ischaemic states or states following a reperfusion.Type: GrantFiled: July 8, 2009Date of Patent: February 3, 2015Assignee: Universität Duisburg-EssenInventors: Herbert De Groot, Christian Mayer, Frank Petrat, Michael Kirsch
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Publication number: 20140231351Abstract: The invention provides permeable magnetically responsive filtration membranes that include a filtration membrane polymer base suitable for fluid filtration; hydrophilic polymers conjugated to the surface of the filtration membrane polymer; and magnetic nanoparticles affixed to the ends of a plurality of the hydrophilic polymers, wherein the hydrophilic polymers are movable with respect to the surface of the filtration membrane polymer surface in the presence of an oscillating magnetic field.Type: ApplicationFiled: August 8, 2012Publication date: August 21, 2014Applicants: Colorado State University Research Foundation, The Board of Trustees of the University of Arkansas, Lehrstuhl fur Technische Chemie II, Universitat Duisburg-EssenInventors: Sumith Ranil WICKRAMASINGHE, Xianghong QIAN, Heath H. HIMSTEDT, Mathias ULBRICHT, Michael J. SEMMENS
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Patent number: 8791092Abstract: This invention provides novel compositions to inhibit the aggregation of amyloid proteins. In various embodiments the compositions comprise a molecular tweezers that binds lysine and/or arginine and thereby inhibits the aggregation of amyloidogenic proteins.Type: GrantFiled: March 5, 2010Date of Patent: July 29, 2014Assignees: The Regents of the University of California, The United States of America as represented by the Department of Veterans Affairs, Massachusetts Institute of Technology, Universitat Duisburg-EssenInventors: Gal Bitan, Akila Shanmugam, Aleksey Lomakin, Thomas Schrader, Frank Gerrit Klarner, Peter Talbiersky, Jolanta Polkowska, Frank Bastkowski, Sharmistha Sinha, Sally Frautschy
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Publication number: 20130189676Abstract: The invention relates to an in vitro method for predicting disease risks, progression of diseases, drug risks, success of treatment and for finding drug targets by looking for one or more genetic modifications in the promoter region of the CHK1 (CHEK1) gene on human chromosome 11q23, the genetic modifications being a substitution thymine for guanine in position ?1143 in the promoter of CHK1, of thymine for cytosine in position ?1400, a substitution of cytosine for thymine in position ?1453 or an insertion of one cytosine in position ?1454 and the genetic modifications being detected individually or in any combinations by way of known methods.Type: ApplicationFiled: November 1, 2012Publication date: July 25, 2013Applicant: Universitat Duisburg-EssenInventor: Universitat Duisburg-Essen
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Patent number: 8321021Abstract: A stimulation system, an implantable electrode device and a method for operating an implantable electrode device are proposed. A simplified implantation, a simple construction and reliable control are made possible by the electrode device being supplied with energy, and controlled, in an exclusively wireless manner via a time-variable magnetic field. The magnetic field is generated by an implanted control device.Type: GrantFiled: July 11, 2008Date of Patent: November 27, 2012Assignee: Universität Duisburg-EssenInventors: Erhard Kisker, Heinrich Wieneke