Abstract: The invention relates to a device (5) for delivery of substances (9) to and removal of bodily substances (22) from a tissue (2) or vessel (25) of a body using an element (6) to be positioned in the tissue (2) or vessel (25).

Abstract: A mutant Pichia pastoris alcohol oxidase 1 (AOX1) promoter of the wild type Pichia pastoris AOX1 promoter (SEQ ID No. 1) comprising at least one mutation selected from the group consisting of: a) a transcription factor binding site (TFBS), b) nucleotides 170 to 235 (?784 to ?719), nucleotides 170 to 191 (?784 to ?763), nucleotides 192 to 213 (?762 to ?741), nucleotides 192 to 210 (?762 to ?744), nucleotides 207 to 209 (?747 to ?745), nucleotides 214 to 235 (?740 to ?719), nucleotides 304 to 350 (?650 to ?604), nucleotides 364 to 393 (?590 to ?561), nucleotides 434 to 508 (?520 to ?446), nucleotides 509 to 551 (?445 to ?403), nucleotides 552 to 560 (?402 to ?394), nucleotides 585 to 617 (?369 to ?337), nucleotides 621 to 660 (?333 to ?294), nucleotides 625 to 683 (?329 to ?271), nucleotides 736 to 741 (?218 to ?213), nucleotides 737 to 738 (?217 to ?216), nucleotides 726 to 755 (?228 to ?199), nucleotides 784 to 800 (?170 to ?154) or nucleotides 823 to 861 (?131 to ?93) of Seq ID No.

Abstract: An assay library comprising 14 fluorescently labeled phosphonate esters which act as serine hydrolase inhibitors is provided as an analytical tool enabling activity based identification of serine hydrolases and characterization of enzyme preparations, protein mixtures and complex proteome samples.

Abstract: The invention relates to a method and a device for determining the parameters of a fluctuating flow of a fluid in a pipe, wherein at least three electrodes that are placed at a distance from one another in the direction of flow are provided in the periphery of the flow, wherein alternating voltage signals are fed to a first upstream transmission electrode arrangement and to a second downstream transmission electrode arrangement and the receiving signals generated by the displacement current are detected in a receiving electrode arrangement located between the transmission electrodes and subjected to a time-discrete cross-correlation. The throughput times of the fluctuations detected by the electrodes are determined on the basis of the results.

Abstract: The invention relates to a method and a device for determining the parameters of a fluctuating flow of a fluid in a pipe, wherein at least three electrodes that are placed at a distance from one another in the direction of flow are provided in the periphery of the flow, wherein alternating voltage signals are fed to a first upstream transmission electrode arrangement and to a second downstream transmission electrode arrangement and the receiving signals generated by the displacement current are detected in a receiving electrode arrangement located between the transmission electrodes and subjected to a time-discrete cross-correlation. The throughput times of the fluctuations detected by the electrodes are determined on the basis of the results.

Abstract: A method and a device for determining the velocity of a mass flow of powdered/granular bulk material in a conduit (1). Periodic disturbances are introduced into the mass flow that affect its electrical properties at at least one first point of the conduit (“point of disturbance”) (SST). Using an electrode mechanism (ME1 . . . ME6) an electrical current is produced by the mass flow at at least one second measuring point situated downstream of the point of disturbance (“measuring point”) (MST), and temporarily occurring changes of the current based on the disturbances introduced upstream are measured via an evaluation circuit (REV). The speed of the mass flow is determined from the time dependency between measured changes and introduced disturbance.

Abstract: A measuring system for measuring the accuracy of the position and track of a machine element moved along a predetermined track. The system includes a predetermined track along which a machine element moves relative thereto and a measuring device for measuring the position of the machine element along the track. The track has a guide of the measuring device, on which a carriage is guided along the track, wherein the machine element can be fastened to the carriage. A component of the measuring device is fastened on the carriage and a drive integrated with the measuring device moves the carriage in a controlled manner along the guide into predetermined positions and at predetermined speeds.

Abstract: A measuring arrangement suitable for checking the geometric and dynamic accuracy of two numerically controlled machine elements which are displaceable with respect to each other. A base body is fastened on a carriage of a machine tool to be tested, on which a linear guide with a linear measuring device is rotatably seated. A measuring element is fastened in a spindle of the machine tool and is connected via a guide with the carriage. The measuring element has three pivot bearings and a further linear guide, as well as further measuring devices for measuring the rotating movements around the pivot bearings and along the further linear guide. Thus the measuring arrangement has six degrees of freedom, wherein four rotary and two translatory joints make possible the registration of individual deviations.