Patents Assigned to UNIVERSITATSKLINIKUM ERLANGEN
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Patent number: 11180511Abstract: The present invention describes a compound of formula (I) which can be used in the diagnosis, treatment or prevention of neurotensin receptor-related conditions such as tumors and hematological malignancies.Type: GrantFiled: August 2, 2017Date of Patent: November 23, 2021Assignee: Friedrich-Alexander-Universität Erlangen-Nürnberg; Universitätsklinikum ErlangenInventors: Olaf Prante, Torsten Kuwert, Peter Gmeiner, Ashutosh Banerjee, Simone Maschauer
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Publication number: 20200377523Abstract: The present invention describes a compound of formula (I) which can be used in the diagnosis, treatment or prevention of neurotensin receptor-related conditions such as tumors and hematological malignancies.Type: ApplicationFiled: August 2, 2017Publication date: December 3, 2020Applicants: Friedrich-Alexander-Universität Erlangen-Nürnberg, Universitätsklinikum ErlangenInventors: Olaf PRANTE, Torsten KUWERT, Peter GMEINER, Ashutosh BANERJEE, Simone MASCHAUER
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Patent number: 9572486Abstract: The invention relates to a device and a method for checking human vision, comprising an image-generating module for generating any test images, an imaging module, used to image the test image provided by the image-generating module on the retina of the eye as a stimulus, the imaging module containing at least one optical component having variable focal length, such that the test image of the image-generating module is perceptible to the eye from virtually simulated and variable distances, an accommodation measuring apparatus, a viewing direction measuring apparatus, and a control and evaluation module, which records and/or further processes the information. The accommodation of the eye can be stimulated by means of the particular test image, and the viewing direction of the eye can be measured simultaneously or in alternation, and fed to a control and evaluation module. Both eyes can be checked simultaneously by generating virtual binocular images.Type: GrantFiled: November 20, 2013Date of Patent: February 21, 2017Assignees: VOIGTMANN GMBH, TALKINGEYES & MORE GMBH, FRIEDRICH-ALEXANDER-UNIVERSITAT ERLANGEN-NURNBERG, UNIVERSITATSKLINIKUM ERLANGENInventors: Peter Voigtmann, Bernhard Hoher, Bernhard Schmauss, Georg Michelson
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Publication number: 20160089027Abstract: The invention relates to a method for photographically observing and/or documenting the fundus of an eye, comprising: producing a lighting beam path by means of a lighting module for lighting at least one partial area of the fundus by using an at least approximately punctiform or at least areally limited lighting source, producing an image plane in the lighting beam path for the creation of photographic recordings, separating the pupil cross-sectional area into a detectable observation region and an undetectable lighting region, producing an image area that contains the image of the fundus on the image plane, dividing the image area in strips in the lighting beam path into a lighted region and unlighted regions, and imaging the third and fourth Purkinje reflection on the image area, wherein at least one Purkinje reflection, the third and/or fourth Purkinje reflection, is located in the unlighted regions of the image area.Type: ApplicationFiled: April 8, 2014Publication date: March 31, 2016Applicants: VOIGTMANN GMBH, TALKINGEYES & MORE GMBH, FRIEDRICH-ALEXANDER-UNIVERSITAT ERLANGEN-NURNBERG, UNIVERSITATSKLINIKUM ERLANGENInventors: Peter VOIGTMANN, Bernhard HOHER, Bernhard SCHMAUSS, Georg MICHELSON, Thomas KOHLER
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Publication number: 20150320306Abstract: The invention relates to a device and a method for checking human vision, comprising an image-generating module for generating any test images, an imaging module, used to image the test image provided by the image-generating module on the retina of the eye as a stimulus, the imaging module containing at least one optical component having variable focal length, such that the test image of the image-generating module is perceptible to the eye from virtually simulated and variable distances, an accommodation measuring apparatus, a viewing direction measuring apparatus, and a control and evaluation module, which records and/or further processes the information. The accommodation of the eye can be stimulated by means of the particular test image, and the viewing direction of the eye can be measured simultaneously or in alternation, and fed to a control and evaluation module. Both eyes can be checked simultaneously by generating virtual binocular images.Type: ApplicationFiled: November 20, 2013Publication date: November 12, 2015Applicants: VOIGTMANN GMBH, UNIVERSITATSKLINIKUM ERLANGEN, FRIEDRICH-ALEXANDER-UNIVERSITAT ERLANGEN-NURNBERG, TALKINGEYES & MORE GMBHInventors: Peter VOIGTMANN, Bernhard HOHER, Bernhard SCHMAUSS, Georg MICHELSON
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Publication number: 20150317796Abstract: The present invention relates to a non-invasive method for predicting the responsiveness of a human subject suffering from inflammatory disease to a treatment with a therapy against said inflammatory disease using brain imaging techniques. Furthermore, the present invention relates to a pharmaceutical composition comprising an active ingredient for the treatment of human subjects suffering from inflammatory disease and being identified as responders to therapy against the inflammatory disease according to the method of the invention. Preferably, this invention relates to a non-invasive method for predicting the responsiveness of a human subject suffering from rheumatoid arthritis to a treatment with TNF-antagonists comprising at least one step of brain imaging, preferably with an fMRI apparatus. The present invention shows that response to TNFi depends on the gestalt of brain activity in rheumatoid arthritis (RA) patients.Type: ApplicationFiled: December 11, 2013Publication date: November 5, 2015Applicants: Friedrich-Alexander-Universität Erlangen-Nümberg, Universitätsklinikum ErlangenInventors: Georg SCHETT, Andreas HESS